Symbol Name ID |
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 MGI:102463 |
Age | E7 | E10 | E10.5 | E11 | E11.5 | E12.5 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16.5 | E17 | E17.5 | E18.5 | P |
Immunohistochemistry (section) | 3 | 1 | ||||||||||||||
In situ RNA (section) | 1 | 1 | 1 | 1 | 2 | 1 | 2 | |||||||||
In situ RNA (whole mount) | 1 | 1 | 2 | |||||||||||||
Northern blot | 1 | 1 | 1 | 1 | ||||||||||||
Western blot | 1 | |||||||||||||||
RT-PCR | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 |
Nfatc2 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 (Synonyms: NFAT1, NFAT1-D, NFATp) | |
Results | Reference |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
1 | J:217672 Blazek JD, Malik AM, Tischbein M, Arbones ML, Moore CS, Roper RJ, Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner. Mech Dev. 2015 May;136:133-42 |
5 | J:171469 Burn SF, Webb A, Berry RL, Davies JA, Ferrer-Vaquer A, Hadjantonakis AK, Hastie ND, Hohenstein P, Calcium/NFAT signalling promotes early nephrogenesis. Dev Biol. 2011 Apr 15;352(2):288-98 |
1 | J:254209 Da Silva F, Rocha AS, Motamedi FJ, Massa F, Basboga C, Morrison H, Wagner KD, Schedl A, Coronary Artery Formation Is Driven by Localized Expression of R-spondin3. Cell Rep. 2017 Aug 22;20(8):1745-1754 |
1 | J:206594 Daou N, Lecolle S, Lefebvre S, della Gaspera B, Charbonnier F, Chanoine C, Armand AS, A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis. Development. 2013 Dec;140(24):4914-25 |
1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
3* | J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257 |
3* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:175792 Jelcick AS, Yuan Y, Leehy BD, Cox LC, Silveira AC, Qiu F, Schenk S, Sachs AJ, Morrison MA, Nystuen AM, DeAngelis MM, Haider NB, Genetic variations strongly influence phenotypic outcome in the mouse retina. PLoS One. 2011;6(7):e21858 |
2* | J:205486 Kurabayashi N, Sanada K, Increased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells. Genes Dev. 2013 Dec 15;27(24):2708-21 |
1 | J:277244 LaHaye S, Majumdar U, Yasuhara J, Koenig SN, Matos-Nieves A, Kumar R, Garg V, Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation. Dis Model Mech. 2019 Jun 24;12(6):dmm036764 |
1 | J:123002 Lejard V, Brideau G, Blais F, Salingcarnboriboon R, Wagner G, Roehrl MH, Noda M, Duprez D, Houillier P, Rossert J, Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts. J Biol Chem. 2007 Jun 15;282(24):17665-75 |
1* | J:241781 McElyea SD, Starbuck JM, Tumbleson-Brink DM, Harrington E, Blazek JD, Ghoneima A, Kula K, Roper RJ, Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome. Hum Mol Genet. 2016 Nov 15;25(22):4856-4869 |
1 | J:269498 Nonomura K, Lukacs V, Sweet DT, Goddard LM, Kanie A, Whitwam T, Ranade SS, Fujimori T, Kahn ML, Patapoutian A, Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12817-12822 |
4* | J:44350 Pan S, Koyano-Nakagawa N, Tsuruta L, Amasaki Y, Yokota T, Mori S, Arai N, Arai K, Molecular cloning and functional characterization of murine cDNA encoding transcription factor NFATc. Biochem Biophys Res Commun. 1997 Nov 17;240(2):314-23 |
1 | J:183534 Tu X, Chen J, Lim J, Karner CM, Lee SY, Heisig J, Wiese C, Surendran K, Kopan R, Gessler M, Long F, Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1. PLoS Genet. 2012 Mar;8(3):e1002577 |
1* | J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130 |
2* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
1* | J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48 |
2 | J:198588 Yumoto K, Thomas PS, Lane J, Matsuzaki K, Inagaki M, Ninomiya-Tsuji J, Scott GJ, Ray MK, Ishii M, Maxson R, Mishina Y, Kaartinen V, TGF-beta-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells. J Biol Chem. 2013 May 10;288(19):13467-80 |
1 | J:153636 Zeini M, Hang CT, Lehrer-Graiwer J, Dao T, Zhou B, Chang CP, Spatial and temporal regulation of coronary vessel formation by calcineurin-NFAT signaling. Development. 2009 Oct;136(19):3335-45 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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