Gene Expression Literature Summary

• Symbol: Dct
• Name: dopachrome tautomerase
• ID: MGI:102563

124 matching records from 124 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17.5	E18	E18.5	E19.5	E20	E	P
Immunohistochemistry (section)	1	2	4	3	5	1	4		5	1	4		8		5	3	1	4		2	1	16
In situ RNA (section)	4	2	8	2	16	5	14	1	9	2	14	1	5	1	6	1	2	9	1			14
Immunohistochemistry (whole mount)	1								1		1		1					1			1	2
In situ RNA (whole mount)	3	1	10	3	18	2	12		6		1										1
In situ reporter (knock in)																						1
Western blot																						4
RT-PCR			1		1				1		2		3		1	1		1				10
cDNA clones																					1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dct  dopachrome tautomerase   (Synonyms: TRP-2, TRP2, tyrosinase-related protein-2, Tyrp-2, Tyrp2)
Results	Reference
1	J:157307 Adameyko I, Lallemend F, Aquino JB, Pereira JA, Topilko P, Muller T, Fritz N, Beljajeva A, Mochii M, Liste I, Usoskin D, Suter U, Birchmeier C, Ernfors P, Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin. Cell. 2009 Oct 16;139(2):366-79
2	J:178973 Adameyko I, Lallemend F, Furlan A, Zinin N, Aranda S, Kitambi SS, Blanchart A, Favaro R, Nicolis S, Lubke M, Muller T, Birchmeier C, Suter U, Zaitoun I, Takahashi Y, Ernfors P, Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest. Development. 2012 Jan;139(2):397-410
1	J:173609 Agarwal P, Verzi MP, Nguyen T, Hu J, Ehlers ML, McCulley DJ, Xu SM, Dodou E, Anderson JP, Wei ML, Black BL, The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10. Development. 2011 Jun;138(12):2555-65
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1*	J:272120 Bachg AC, Horsthemke M, Skryabin BV, Klasen T, Nagelmann N, Faber C, Woodham E, Machesky LM, Bachg S, Stange R, Jeong HW, Adams RH, Bahler M, Hanley PJ, Phenotypic analysis of Myo10 knockout (Myo10(tm2/tm2)) mice lacking full-length (motorized) but not brain-specific headless myosin X. Sci Rep. 2019 Jan 24;9(1):597
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2*	J:78163 Baxter LL, Pavan WJ, The oculocutaneous albinism type IV gene Matp is a new marker of pigment cell precursors during mouse embryonic development. Mech Dev. 2002 Aug;116(1-2):209-12
2*	J:86959 Baxter LL, Pavan WJ, Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development. Gene Expr Patterns. 2003 Dec;3(6):703-7
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1	J:214677 Bohnenpoll T, Trowe MO, Wojahn I, Taketo MM, Petry M, Kispert A, Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear. Dev Biol. 2014 Jul 1;391(1):54-65
3	J:138178 Brito FC, Kos L, Timeline and distribution of melanocyte precursors in the mouse heart. Pigment Cell Melanoma Res. 2008 Aug;21(4):464-70
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2	J:160209 Buac K, Xu M, Cronin J, Weeraratna AT, Hewitt SM, Pavan WJ, NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation. Pigment Cell Melanoma Res. 2009 Dec;22(6):773-84
2	J:197180 Buniello A, Hardisty-Hughes RE, Pass JC, Bober E, Smith RJ, Steel KP, Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS One. 2013;8(2):e56274
1	J:92326 Burton Q, Cole LK, Mulheisen M, Chang W, Wu DK, The role of Pax2 in mouse inner ear development. Dev Biol. 2004 Aug 1;272(1):161-75
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1	J:214343 Cai Z, Grobe K, Zhang X, Role of heparan sulfate proteoglycans in optic disc and stalk morphogenesis. Dev Dyn. 2014 Oct;243(10):1310-6
1	J:194534 Chang CY, Pasolli HA, Giannopoulou EG, Guasch G, Gronostajski RM, Elemento O, Fuchs E, NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. Nature. 2013 Mar 7;495(7439):98-102
1	J:314168 Chen W, Liu X, Li W, Shen H, Zeng Z, Yin K, Priest JR, Zhou Z, Single-cell transcriptomic landscape of cardiac neural crest cell derivatives during development. EMBO Rep. 2021 Nov 4;22(11):e52389
2	J:104329 Choo D, Ward J, Reece A, Dou H, Lin Z, Greinwald J, Molecular mechanisms underlying inner ear patterning defects in kreisler mutants. Dev Biol. 2006 Jan 15;289(2):308-17
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1	J:160023 Cossais F, Sock E, Hornig J, Schreiner S, Kellerer S, Bosl MR, Russell S, Wegner M, Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression. Dev Biol. 2010 May 1;341(1):267-81
1	J:211299 Denecker G, Vandamme N, Akay O, Koludrovic D, Taminau J, Lemeire K, Gheldof A, De Craene B, Van Gele M, Brochez L, Udupi GM, Rafferty M, Balint B, Gallagher WM, Ghanem G, Huylebroeck D, Haigh J, van den Oord J, Larue L, Davidson I, Marine JC, Berx G, Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression. Cell Death Differ. 2014 Aug;21(8):1250-61
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:196080 Elsen GE, Hodge RD, Bedogni F, Daza RA, Nelson BR, Shiba N, Reiner SL, Hevner RF, The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
11	J:355488 Erjavec E, Angee C, Hadjadj D, Passet B, David P, Kostic C, Dode E, Zanlonghi X, Cagnard N, Nedelec B, Crippa SV, Bole-Feysot C, Zarhrate M, Creuzet S, Castille J, Vilotte JL, Calvas P, Plaisancie J, Chassaing N, Kaplan J, Rozet JM, Taie LF, Congenital microcoria deletion in mouse links Sox21 dysregulation to disease and suggests a role for TGFB2 in glaucoma and myopia. Am J Hum Genet. 2024 Oct 3;111(10):2265-2282
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1	J:316293 Fujimura N, Klimova L, Antosova B, Smolikova J, Machon O, Kozmik Z, Genetic interaction between Pax6 and beta-catenin in the developing retinal pigment epithelium. Dev Genes Evol. 2015 Apr;225(2):121-8
3	J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198
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1	J:117334 Gritli-Linde A, Hallberg K, Harfe BD, Reyahi A, Kannius-Janson M, Nilsson J, Cobourne MT, Sharpe PT, McMahon AP, Linde A, Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell. 2007 Jan;12(1):99-112
1	J:153219 Grossmann KS, Wende H, Paul FE, Cheret C, Garratt AN, Zurborg S, Feinberg K, Besser D, Schulz H, Peles E, Selbach M, Birchmeier W, Birchmeier C, The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16704-9
2*	J:295480 Haage A, Wagner K, Deng W, Venkatesh B, Mitchell C, Goodwin K, Bogutz A, Lefebvre L, Van Raamsdonk CD, Tanentzapf G, Precise coordination of cell-ECM adhesion is essential for efficient melanoblast migration during development. Development. 2020 Jul 17;147(14):dev184234
1*	J:105843 Hakami RM, Hou L, Baxter LL, Loftus SK, Southard-Smith EM, Incao A, Cheng J, Pavan WJ, Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage. Mech Dev. 2006 Feb;123(2):124-34
7	J:185553 Hari L, Miescher I, Shakhova O, Suter U, Chin L, Taketo M, Richardson WD, Kessaris N, Sommer L, Temporal control of neural crest lineage generation by Wnt/beta-catenin signaling. Development. 2012 Jun;139(12):2107-17
2*	J:13562 Hodgkinson CA, Moore KJ, Nakayama A, Steingrimsson E, Copeland NG, Jenkins NA, Arnheiter H, Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. Cell. 1993 Jul 30;74(2):395-404
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
2	J:94374 Horsford DJ, Nguyen MT, Sellar GC, Kothary R, Arnheiter H, McInnes RR, Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Development. 2005 Jan;132(1):177-87
1	J:213982 Hozumi H, Takeda K, Yoshida-Amano Y, Takemoto Y, Kusumi R, Fukuzaki-Dohi U, Higashitani A, Yamamoto H, Shibahara S, Impaired development of melanoblasts in the black-eyed white Mitf(mi-bw) mouse, a model for auditory-pigmentary disorders. Genes Cells. 2012 Jun;17(6):494-508
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9*	J:119300 Jiao Z, Zhang ZG, Hornyak TJ, Hozeska A, Zhang RL, Wang Y, Wang L, Roberts C, Strickland FM, Chopp M, Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation. Dev Biol. 2006 Aug 15;296(2):396-408
2	J:229073 Kam MK, Cheung MC, Zhu JJ, Cheng WW, Sat EW, Tam PK, Lui VC, Perturbation of Hoxb5 signaling in vagal and trunk neural crest cells causes apoptosis and neurocristopathies in mice. Cell Death Differ. 2014 Feb;21(2):278-89
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3	J:295923 McMenamin PG, Shields GT, Seyed-Razavi Y, Kalirai H, Insall RH, Machesky LM, Coupland SE, Melanoblasts Populate the Mouse Choroid Earlier in Development Than Previously Described. Invest Ophthalmol Vis Sci. 2020 Aug 3;61(10):33
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1*	J:194281 Silver DL, Leeds KE, Hwang HW, Miller EE, Pavan WJ, The EJC component Magoh regulates proliferation and expansion of neural crest-derived melanocytes. Dev Biol. 2013 Mar 15;375(2):172-81
1	J:335084 Song H, Zhao XB, Chu QS, Zhang J, Gao L, Liao XH, Expression dynamics of lymphoid enhancer-binding factor 1 in terminal Schwann cells, dermal papilla, and interfollicular epidermis. Dev Dyn. 2023 Apr;252(4):527-535
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