Gene Expression Literature Summary

• Symbol: Fen1
• Name: flap structure specific endonuclease 1
• ID: MGI:102779

7 matching records from 7 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3	E4	E7	E9.5	E11	E12.5	E14.5	E15	E16.5	E17	E18.5	P
Immunohistochemistry (section)												1
In situ RNA (section)						1	2		1
Immunohistochemistry (whole mount)	1	1
In situ reporter (knock in)				1			1					1
Western blot												2
RT-PCR			1		1			1		1	1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fen1  flap structure specific endonuclease 1
Results	Reference
3*	J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
5*	J:101008 Emoto M, Miki M, Sarker AH, Nakamura T, Seki Y, Seki S, Ikeda S, Structure and transcription promoter activity of mouse flap endonuclease 1 gene: alternative splicing and bidirectional promoter. Gene. 2005 Aug 29;357(1):47-54
1	J:212924 Katyal S, Lee Y, Nitiss KC, Downing SM, Li Y, Shimada M, Zhao J, Russell HR, Petrini JH, Nitiss JL, McKinnon PJ, Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes. Nat Neurosci. 2014 Jun;17(6):813-21
6	J:199673 Kleppa L, Mari PO, Larsen E, Lien GF, Godon C, Theil AF, Nesse GJ, Wiksen H, Vermeulen W, Giglia-Mari G, Klungland A, Kinetics of endogenous mouse FEN1 in base excision repair. Nucleic Acids Res. 2012 Oct;40(18):9044-59
1	J:267889 Moon S, Im SK, Kim N, Youn H, Park UH, Kim JY, Kim AR, An SJ, Kim JH, Sun W, Hwang JT, Kim EJ, Um SJ, Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018 Nov 2;9(11):1118
2	J:112968 van den Broek WJ, Nelen MR, van der Heijden GW, Wansink DG, Wieringa B, Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1. FEBS Lett. 2006 Oct 2;580(22):5208-14