Gene Expression Literature Summary

• Symbol: Barx1
• Name: BarH-like homeobox 1
• ID: MGI:103124

94 matching records from 94 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E5.5	E6.5	E7.5	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)											1	1				2						2			1
In situ RNA (section)						3		9		8	2	6	1	8		12		2		6		1	1	5		6	6
In situ RNA (whole mount)						10	2	30	1	11		6	2	8	1	5		2		1		1				2	1
Northern blot	1	1	1	1		1		1		1		2		1		1		2		1		2					2
Western blot												1		1		1
RT-PCR					1	3	1	6	1	1	2	3	2	6	2	2	2	3	2	2	2	2	1	3	1	1	3
cDNA clones						1		1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Barx1  BarH-like homeobox 1
Results	Reference
2	J:310312 Abe M, Cox TC, Firulli AB, Kanai SM, Dahlka J, Lim KC, Engel JD, Clouthier DE, GATA3 is essential for separating patterning domains during facial morphogenesis. Development. 2021 Sep 1;148(17):dev199534
1	J:207610 Akiyama R, Kawakami H, Taketo MM, Evans SM, Wada N, Petryk A, Kawakami Y, Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the beta-catenin pathway. Dev Biol. 2014 Mar 1;387(1):37-48
1	J:78219 Aubin J, Dery U, Lemieux M, Chailler P, Jeannotte L, Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling. Development. 2002 Sep;129(17):4075-87
2	J:152830 Balic A, Adams D, Mina M, Prx1 and Prx2 cooperatively regulate the morphogenesis of the medial region of the mandibular process. Dev Dyn. 2009 Sep 23;238(10):2599-2613
1	J:220864 Billmyre KK, Klingensmith J, Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation. Dev Dyn. 2015 Apr;244(4):564-76
2*	J:278801 Bloomquist RF, Fowler TE, An Z, Yu TY, Abdilleh K, Fraser GJ, Sharpe PT, Streelman JT, Developmental plasticity of epithelial stem cells in tooth and taste bud renewal. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17858-17866
1*	J:116770 Britanova O, Depew MJ, Schwark M, Thomas BL, Miletich I, Sharpe P, Tarabykin V, Satb2 haploinsufficiency phenocopies 2q32-q33 deletions, whereas loss suggests a fundamental role in the coordination of jaw development. Am J Hum Genet. 2006 Oct;79(4):668-78
2*	J:214666 Brunskill EW, Potter AS, Distasio A, Dexheimer P, Plassard A, Aronow BJ, Potter SS, A gene expression atlas of early craniofacial development. Dev Biol. 2014 Jul 15;391(2):133-46
1	J:268361 Byrnes LE, Wong DM, Subramaniam M, Meyer NP, Gilchrist CL, Knox SM, Tward AD, Ye CJ, Sneddon JB, Lineage dynamics of murine pancreatic development at single-cell resolution. Nat Commun. 2018 Sep 25;9(1):3922
1*	J:316185 Cesario J, Ha S, Kim J, Kataria N, Jeong J, Candidate positive targets of LHX6 and LHX8 transcription factors in the developing upper jaw. Gene Expr Patterns. 2021 Nov 30;43:119227
1*	J:59338 Clouthier DE, Williams SC, Yanagisawa H, Wieduwilt M, Richardson JA, Yanagisawa M, Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Dev Biol. 2000 Jan 1;217(1):10-24
1	J:152420 Denaxa M, Sharpe PT, Pachnis V, The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition. Dev Biol. 2009 Sep 15;333(2):324-36
1	J:79553 Depew MJ, Lufkin T, Rubenstein JL, Specification of jaw subdivisions by Dlx genes. Science. 2002 Oct 11;298(5592):381-5
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:294823 Fabik J, Kovacova K, Kozmik Z, Machon O, Neural crest cells require Meis2 for patterning the mandibular arch via the Sonic hedgehog pathway. Biol Open. 2020 Jul 2;9(6):bio052043
1	J:213659 Fausett SR, Brunet LJ, Klingensmith J, BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis. Dev Biol. 2014 Jul 1;391(1):111-24
3	J:49552 Ferguson CA, Tucker AS, Christensen L, Lau AL, Matzuk MM, Sharpe PT, Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition. Genes Dev. 1998 Aug 15;12(16):2636-49
1	J:198516 Fujita K, Taya Y, Shimazu Y, Aoba T, Soeno Y, Molecular signaling at the fusion stage of the mouse mandibular arch: involvement of insulin-like growth factor family. Int J Dev Biol. 2013;57(5):399-406
1	J:183770 Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H, Tbx1 regulates oral epithelial adhesion and palatal development. Hum Mol Genet. 2012 Jun 1;21(11):2524-37
2	J:157954 Grainger S, Savory JG, Lohnes D, Cdx2 regulates patterning of the intestinal epithelium. Dev Biol. 2010 Mar 1;339(1):155-65
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:268293 Guo S, Zhang Y, Zhou T, Wang D, Weng Y, Chen Q, Ma J, Li YP, Wang L, GATA4 as a novel regulator involved in the development of the neural crest and craniofacial skeleton via Barx1. Cell Death Differ. 2018 Nov;25(11):1996-2009
2	J:299735 Han L, Chaturvedi P, Kishimoto K, Koike H, Nasr T, Iwasawa K, Giesbrecht K, Witcher PC, Eicher A, Haines L, Lee Y, Shannon JM, Morimoto M, Wells JM, Takebe T, Zorn AM, Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis. Nat Commun. 2020 Aug 27;11(1):4158
1	J:214763 He F, Hu X, Xiong W, Li L, Lin L, Shen B, Yang L, Gu S, Zhang Y, Chen Y, Directed Bmp4 expression in neural crest cells generates a genetic model for the rare human bony syngnathia birth defect. Dev Biol. 2014 Jul 15;391(2):170-81
2*	J:93234 Hecksher-Sorensen J, Watson RP, Lettice LA, Serup P, Eley L, De Angelis C, Ahlgren U, Hill RE, The splanchnic mesodermal plate directs spleen and pancreatic laterality, and is regulated by Bapx1/Nkx3.2. Development. 2004 Oct;131(19):4665-75
1	J:90847 Hirota J, Mombaerts P, The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8751-5
6*	J:225747 Jayewickreme CD, Shivdasani RA, Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1. Dev Biol. 2015 Sep 1;405(1):21-32
2	J:187966 Jeong J, Cesario J, Zhao Y, Burns L, Westphal H, Rubenstein JL, Cleft palate defect of Dlx1/2-/- mutant mice is caused by lack of vertical outgrowth in the posterior palate. Dev Dyn. 2012 Nov;241(11):1757-69
6*	J:39325 Jones FS, Kioussi C, Copertino DW, Kallunki P, Holst BD, Edelman GM, Barx2, a new homeobox gene of the Bar class, is expressed in neural and craniofacial structures during development. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2632-7
16*	J:98305 Kim BM, Buchner G, Miletich I, Sharpe PT, Shivdasani RA, The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling. Dev Cell. 2005 Apr;8(4):611-22
6	J:128378 Kim BM, Miletich I, Mao J, McMahon AP, Sharpe PA, Shivdasani RA, Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development. 2007 Oct;134(20):3603-13
4	J:170489 Kim BM, Woo J, Kanellopoulou C, Shivdasani RA, Regulation of mouse stomach development and Barx1 expression by specific microRNAs. Development. 2011 Mar;138(6):1081-6
1	J:265501 Kim H, Langohr IM, Faisal M, McNulty M, Thorn C, Kim J, Ablation of Ezh2 in neural crest cells leads to aberrant enteric nervous system development in mice. PLoS One. 2018;13(8):e0203391
1	J:128941 Ko SO, Chung IH, Xu X, Oka S, Zhao H, Cho ES, Deng C, Chai Y, Smad4 is required to regulate the fate of cranial neural crest cells. Dev Biol. 2007 Dec 1;312(1):435-47
3	J:243780 Li F, Fu G, Liu Y, Miao X, Li Y, Yang X, Zhang X, Yu D, Gan L, Qiu M, Chen Y, Zhang Z, Zhang Z, ISLET1-Dependent beta-Catenin/Hedgehog Signaling Is Required for Outgrowth of the Lower Jaw. Mol Cell Biol. 2017 Apr 15;37(8)
2	J:175262 Lin C, Fisher AV, Yin Y, Maruyama T, Veith GM, Dhandha M, Huang GJ, Hsu W, Ma L, The inductive role of Wnt-beta-Catenin signaling in the formation of oral apparatus. Dev Biol. 2011 Aug 1;356(1):40-50
1	J:87220 Liu W, Selever J, Lu MF, Martin JF, Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration. Development. 2003 Dec;130(25):6375-85
1*	J:99697 Liu W, Selever J, Murali D, Sun X, Brugger SM, Ma L, Schwartz RJ, Maxson R, Furuta Y, Martin JF, Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol. 2005 Jul 15;283(2):282-93
1	J:97214 Liu W, Sun X, Braut A, Mishina Y, Behringer RR, Mina M, Martin JF, Distinct functions for Bmp signaling in lip and palate fusion in mice. Development. 2005 Mar;132(6):1453-61
1	J:125511 Loomes KM, Stevens SA, O'brien ML, Gonzalez DM, Ryan MJ, Segalov M, Dormans NJ, Mimoto MS, Gibson JD, Sewell W, Schaffer AA, Nah HD, Rappaport EF, Pratt SC, Dunwoodie SL, Kusumi K, Dll3 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects. Dev Dyn. 2007 Oct;236(10):2943-51
1*	J:149571 MacKenzie B, Wolff R, Lowe N, Billington CJ Jr, Peterson A, Schmidt B, Graf D, Mina M, Gopalakrishnan R, Petryk A, Twisted gastrulation limits apoptosis in the distal region of the mandibular arch in mice. Dev Biol. 2009 Apr 1;328(1):13-23
1	J:190291 Madison BB, McKenna LB, Dolson D, Epstein DJ, Kaestner KH, FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine. J Biol Chem. 2009 Feb 27;284(9):5936-44
2	J:214981 Matsui M, Klingensmith J, Multiple tissue-specific requirements for the BMP antagonist Noggin in development of the mammalian craniofacial skeleton. Dev Biol. 2014 Aug 15;392(2):168-81
2	J:147041 Matsuyama M, Aizawa S, Shimono A, Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium. PLoS Genet. 2009 Mar;5(3):e1000427
1*	J:241394 Mattiske T, Lee K, Gecz J, Friocourt G, Shoubridge C, Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene. Hum Mol Genet. 2016 Dec 15;25(24):5433-5443
3	J:103322 Miletich I, Buchner G, Sharpe PT, Barx1 and evolutionary changes in feeding. J Anat. 2005 Nov;207(5):619-22
1	J:144017 Minoux M, Antonarakis GS, Kmita M, Duboule D, Rijli FM, Rostral and caudal pharyngeal arches share a common neural crest ground pattern. Development. 2009 Feb;136(4):637-45
3*	J:130823 Mitsiadis TA, Drouin J, Deletion of the Pitx1 genomic locus affects mandibular tooth morphogenesis and expression of the Barx1 and Tbx1 genes. Dev Biol. 2008 Jan 15;313(2):887-96
3	J:164590 Mitsiadis TA, Graf D, Luder H, Gridley T, Bluteau G, BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation. Development. 2010 Sep;137(18):3025-35
5	J:46754 Mitsiadis TA, Mucchielli ML, Raffo S, Proust JP, Koopman P, Goridis C, Expression of the transcription factors Otlx2, Barx1 and Sox9 during mouse odontogenesis. Eur J Oral Sci. 1998 Jan;106 Suppl 1:112-6
1	J:105263 Moon AM, Guris DL, Seo JH, Li L, Hammond J, Talbot A, Imamoto A, Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes. Dev Cell. 2006 Jan;10(1):71-80
4	J:261627 Mori K, Nakamura H, Kurooka H, Miyachi H, Tamada K, Sugai M, Takumi T, Yokota Y, Id2 determines intestinal identity through repression of the foregut transcription factor, Irx5. Mol Cell Biol. 2018 Feb 20;
2	J:43528 Mucchielli ML, Mitsiadis TA, Raffo S, Brunet JF, Proust JP, Goridis C, Mouse Otlx2/RIEG expression in the odontogenic epithelium precedes tooth initiation and requires mesenchyme-derived signals for its maintenance. Dev Biol. 1997 Sep 15;189(2):275-84
2	J:254493 Munoz-Bravo JL, Flores-Martinez A, Herrero-Martin G, Puri S, Taketo MM, Rojas A, Hebrok M, Cano DA, Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. PLoS One. 2016;11(10):e0164714
2*	J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062
5*	J:198258 Noguchi TK, Ishimine H, Nakajima Y, Watanabe-Susaki K, Shigeta N, Yamakawa N, Wang PC, Asashima M, Kurisaki A, Novel cell surface genes expressed in the stomach primordium during gastrointestinal morphogenesis of mouse embryos. Gene Expr Patterns. 2012 Mar-Apr;12(3-4):154-63
2	J:81591 Obara N, Expression of the neural cell adhesion molecule during mouse tooth development. Connect Tissue Res. 2002;43(2-3):212-5
1*	J:163653 Ohazama A, Haworth KE, Ota MS, Khonsari RH, Sharpe PT, Ectoderm, endoderm, and the evolution of heterodont dentitions. Genesis. 2010 Jun;48(6):382-9
1	J:146634 Ohazama A, Haycraft CJ, Seppala M, Blackburn J, Ghafoor S, Cobourne M, Martinelli DC, Fan CM, Peterkova R, Lesot H, Yoder BK, Sharpe PT, Primary cilia regulate Shh activity in the control of molar tooth number. Development. 2009 Mar;136(6):897-903
3	J:90053 Ohazama A, Hu Y, Schmidt-Ullrich R, Cao Y, Scheidereit C, Karin M, Sharpe PT, A dual role for Ikk alpha in tooth development. Dev Cell. 2004 Feb;6(2):219-27
1	J:336513 Patzek S, Liu Z, de la O S, Chang S, Byrnes LE, Zhang X, Ornitz DM, Sneddon JB, Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia. iScience. 2023 Apr 21;26(4):106500
1	J:345835 Qiu C, Martin BK, Welsh IC, Daza RM, Le TM, Huang X, Nichols EK, Taylor ML, Fulton O, O'Day DR, Gomes AR, Ilcisin S, Srivatsan S, Deng X, Disteche CM, Noble WS, Hamazaki N, Moens CB, Kimelman D, Cao J, Schier AF, Spielmann M, Murray SA, Trapnell C, Shendure J, A single-cell time-lapse of mouse prenatal development from gastrula to birth. Nature. 2024 Feb;626(8001):1084-1093
1	J:344102 Racedo SE, Liu Y, Shi L, Zheng D, Morrow BE, Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals. Dev Biol. 2024 Feb;506:72-84
3	J:246236 Rana MS, Theveniau-Ruissy M, De Bono C, Mesbah K, Francou A, Rammah M, Dominguez JN, Roux M, Laforest B, Anderson RH, Mohun T, Zaffran S, Christoffels VM, Kelly RG, Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart. Circ Res. 2014 Oct 10;115(9):790-9
2	J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7
7*	J:151467 Smith TM, Wang X, Zhang W, Kulyk W, Nazarali AJ, Hoxa2 plays a direct role in murine palate development. Dev Dyn. 2009 Aug 3;238(9):2364-2373
2	J:179732 Stringer EJ, Duluc I, Saandi T, Davidson I, Bialecka M, Sato T, Barker N, Clevers H, Pritchard CA, Winton DJ, Wright NA, Freund JN, Deschamps J, Beck F, Cdx2 determines the fate of postnatal intestinal endoderm. Development. 2012 Feb;139(3):465-74
7	J:137641 Stringer EJ, Pritchard CA, Beck F, Cdx2 initiates histodifferentiation of the midgut endoderm. FEBS Lett. 2008 Jul 23;582(17):2555-60
2	J:241567 Tavares ALP, Cox TC, Maxson RM, Ford HL, Clouthier DE, Negative regulation of endothelin signaling by SIX1 is required for proper maxillary development. Development. 2017 Jun 01;144(11):2021-2031
2*	J:275274 Teng CS, Yen HY, Barske L, Smith B, Llamas J, Segil N, Go J, Sanchez-Lara PA, Maxson RE, Crump JG, Requirement for Jagged1-Notch2 signaling in patterning the bones of the mouse and human middle ear. Sci Rep. 2017 May 31;7(1):2497
3	J:46750 Thomas BL, Sharpe PT, Patterning of the murine dentition by homeobox genes. Eur J Oral Sci. 1998 Jan;106 Suppl 1:48-54
1	J:44838 Thomas BL, Tucker AS, Qui M, Ferguson CA, Hardcastle Z, Rubenstein JL, Sharpe PT, Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition. Development. 1997 Dec;124(23):4811-8
2	J:139045 Thomason HA, Dixon MJ, Dixon J, Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling. Dev Biol. 2008 Sep 1;321(1):273-82
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
23*	J:26186 Tissier-Seta JP, Mucchielli ML, Mark M, Mattei MG, Goridis C, Brunet JF, Barx1, a new mouse homeodomain transcription factor expressed in cranio-facial ectomesenchyme and the stomach. Mech Dev. 1995 May;51(1):3-15
4	J:58999 Trumpp A, Depew MJ, Rubenstein JL, Bishop JM, Martin GR, Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes Dev. 1999 Dec 1;13(23):3136-48
10	J:175540 Tsau C, Ito M, Gromova A, Hoffman MP, Meech R, Makarenkova HP, Barx2 and Fgf10 regulate ocular glands branching morphogenesis by controlling extracellular matrix remodeling. Development. 2011 Aug;138(15):3307-17
2*	J:48939 Tucker AS, Al Khamis A, Sharpe PT, Interactions between Bmp-4 and Msx-1 act to restrict gene expression to odontogenic mesenchyme. Dev Dyn. 1998 Aug;212(4):533-9
1	J:148724 Verzi MP, Stanfel MN, Moses KA, Kim BM, Zhang Y, Schwartz RJ, Shivdasani RA, Zimmer WE, Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development. Gastroenterology. 2009 May;136(5):1701-10
1	J:166759 Villasenor A, Chong DC, Henkemeyer M, Cleaver O, Epithelial dynamics of pancreatic branching morphogenesis. Development. 2010 Dec;137(24):4295-305
1*	J:215297 Voronov D, Gromova A, Liu D, Zoukhri D, Medvinsky A, Meech R, Makarenkova HP, Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration. Invest Ophthalmol Vis Sci. 2013 May;54(5):3115-25
2	J:149542 Wang XP, O'Connell DJ, Lund JJ, Saadi I, Kuraguchi M, Turbe-Doan A, Cavallesco R, Kim H, Park PJ, Harada H, Kucherlapati R, Maas RL, Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood. Development. 2009 Jun;136(11):1939-49
3*	J:125229 Welsh IC, Hagge-Greenberg A, O'brien TP, A dosage-dependent role for Spry2 in growth and patterning during palate development. Mech Dev. 2007 Sep-Oct;124(9-10):746-61
1	J:264402 Welsh IC, Hart J, Brown JM, Hansen K, Rocha Marques M, Aho RJ, Grishina I, Hurtado R, Herzlinger D, Ferretti E, Garcia-Garcia MJ, Selleri L, Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface. J Anat. 2018 Aug;233(2):222-242
6	J:154916 Welsh IC, O'Brien TP, Signaling integration in the rugae growth zone directs sequential SHH signaling center formation during the rostral outgrowth of the palate. Dev Biol. 2009 Dec 1;336(1):53-67
3	J:175765 Woo J, Miletich I, Kim BM, Sharpe PT, Shivdasani RA, Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation. PLoS One. 2011;6(7):e22493
3	J:232140 Xu J, Liu H, Lan Y, Aronow BJ, Kalinichenko VV, Jiang R, A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development. PLoS Genet. 2016 Jan;12(1):e1005769
1*	J:337974 Yadav US, Biswas T, Singh PN, Gupta P, Chakraborty S, Delgado I, Zafar H, Capellini TD, Torres M, Bandyopadhyay A, Molecular mechanism of synovial joint site specification and induction in developing vertebrate limbs. Development. 2023 Jul 1;150(13)
1	J:106091 Yamagishi C, Yamagishi H, Maeda J, Tsuchihashi T, Ivey K, Hu T, Srivastava D, Sonic hedgehog is essential for first pharyngeal arch development. Pediatr Res. 2006 Mar;59(3):349-54
3*	J:330234 Zbasnik N, Dolan K, Buczkowski SA, Green RM, Hallgrimsson B, Marcucio RS, Moon AM, Fish JL, Fgf8 dosage regulates jaw shape and symmetry through pharyngeal-cardiac tissue relationships. Dev Dyn. 2022 Oct;251(10):1711-1727
2	J:183887 Zhang Y, Blackwell EL, McKnight MT, Knutsen GR, Vu WT, Ruest LB, Specific inactivation of Twist1 in the mandibular arch neural crest cells affects the development of the ramus and reveals interactions with hand2. Dev Dyn. 2012 May;241(5):924-40
1*	J:139188 Zhao H, Oka K, Bringas P, Kaartinen V, Chai Y, TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol. 2008 Aug 1;320(1):19-29
1	J:205040 Zhou J, Gao Y, Lan Y, Jia S, Jiang R, Pax9 regulates a molecular network involving Bmp4, Fgf10, Shh signaling and the Osr2 transcription factor to control palate morphogenesis. Development. 2013 Dec;140(23):4709-18