Gene Expression Literature Summary

• Symbol: Atp6v1b1
• Name: ATPase, H+ transporting, lysosomal V1 subunit B1
• ID: MGI:103285

28 matching records from 28 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E9	E11	E11.5	E12.5	E13	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)								1		2		3			1	2	1		11
In situ RNA (section)		1		1	1	1		2		2	1	1	1		1	1		1	4
In situ RNA (whole mount)										1
In situ reporter (knock in)																			1
Western blot							1	1		1		2		1		1			2
RT-PCR	1		1		1	1	1	1	2	1		1	1	2	1	2			8

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Atp6v1b1  ATPase, H+ transporting, lysosomal V1 subunit B1   (Synonyms: Atp6b1, D630030L16Rik, D630039P21Rik, lysosomal 56/58kDa, Vpp-3, Vpp3)
Results	Reference
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
11	J:84744 Dou H, Finberg K, Cardell EL, Lifton R, Choo D, Mice lacking the B1 subunit of H+ -ATPase have normal hearing. Hear Res. 2003 Jun;180(1-2):76-84
1	J:234059 Elias BC, Das A, Parekh DV, Mernaugh G, Adams R, Yang Z, Brakebusch C, Pozzi A, Marciano DK, Carroll TJ, Zent R, Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development. J Cell Sci. 2015 Dec 1;128(23):4293-305
3	J:355097 Gao C, Chen L, Chen E, Tsilosani A, Xia Y, Zhang W, Generation of Distal Renal Segments Involves a Unique Population of Aqp2 + Progenitor Cells. J Am Soc Nephrol. 2021 Dec 1;32(12):3035-3049
2	J:355111 Gao C, Zhang L, Chen E, Zhang W, Aqp2(+) Progenitor Cells Maintain and Repair Distal Renal Segments. J Am Soc Nephrol. 2022 Jul;33(7):1357-1376
4*	J:320193 Golder ZJ, Karet Frankl FE, Extra-renal locations of the a4 subunit of H(+)ATPase. BMC Cell Biol. 2016 Jul 2;17(1):27
1	J:241013 Grassmeyer J, Mukherjee M, deRiso J, Hettinger C, Bailey M, Sinha S, Visvader JE, Zhao H, Fogarty E, Surendran K, Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression. Dev Biol. 2017 Apr 01;424(1):77-89
2*	J:333283 Guan N, Kobayashi H, Ishii K, Davidoff O, Sha F, Ikizler TA, Hao CM, Chandel NS, Haase VH, Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency. Kidney Int. 2022 Jul;102(1):108-120
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
6	J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851
1	J:291050 Ide S, Finer G, Maezawa Y, Onay T, Souma T, Scott R, Ide K, Akimoto Y, Li C, Ye M, Zhao X, Baba Y, Minamizuka T, Jin J, Takemoto M, Yokote K, Quaggin SE, Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development. J Am Soc Nephrol. 2018 Dec;29(12):2795-2808
3	J:154589 Jeong HW, Jeon US, Koo BK, Kim WY, Im SK, Shin J, Cho Y, Kim J, Kong YY, Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice. J Clin Invest. 2009 Nov;119(11):3290-300
12*	J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46
1*	J:162757 Kawamura N, Tabata H, Sun-Wada GH, Wada Y, Optic Nerve Compression and Retinal Degeneration in Tcirg1 Mutant Mice Lacking the Vacuolar-Type H-ATPase a3 Subunit. PLoS One. 2010;5(8):e12086
5*	J:128432 Kawasaki-Nishi S, Yamaguchi A, Forgac M, Nishi T, Tissue specific expression of the splice variants of the mouse vacuolar proton-translocating ATPase a4 subunit. Biochem Biophys Res Commun. 2007 Dec 28;364(4):1032-6
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:333405 Kurtzeborn K, Kwon HN, Iaroshenko V, Faisal I, Ambroz M, Jin X, Qureshi T, Kupari J, Ihermann-Hella A, Vaananen J, Tyynismaa H, Bousova I, Park S, Kuure S, Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney. BMC Biol. 2022 May 13;20(1):112
2	J:199292 Li X, Sanneman JD, Harbidge DG, Zhou F, Ito T, Nelson R, Picard N, Chambrey R, Eladari D, Miesner T, Griffith AJ, Marcus DC, Wangemann P, SLC26A4 Targeted to the Endolymphatic Sac Rescues Hearing and Balance in Slc26a4 Mutant Mice. PLoS Genet. 2013 Jul;9(7):e1003641
1*	J:188593 Norgett EE, Golder ZJ, Lorente-Canovas B, Ingham N, Steel KP, Frankl FE, Atp6v0a4 knockout mouse is a model of distal renal tubular acidosis with hearing loss, with additional extrarenal phenotype. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13775-80
1	J:212428 Raft S, Andrade LR, Shao D, Akiyama H, Henkemeyer M, Wu DK, Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear. Dev Biol. 2014 Jun 1;390(1):51-67
1	J:216308 Ruan YC, Wang Y, Da Silva N, Kim B, Diao RY, Hill E, Brown D, Chan HC, Breton S, CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway. J Cell Sci. 2014 Oct 15;127(Pt 20):4396-408
2*	J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188
1*	J:20867 van Hille B, Richener H, Schmid P, Puettner I, Green JR, Bilbe G, Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms. Biochem J. 1994 Oct 1;303(Pt 1):191-8
1	J:223640 Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S, The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. PLoS One. 2009;4(2):e4471
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:249938 Werth M, Schmidt-Ott KM, Leete T, Qiu A, Hinze C, Viltard M, Paragas N, Shawber CJ, Yu W, Lee P, Chen X, Sarkar A, Mu W, Rittenberg A, Lin CS, Kitajewski J, Al-Awqati Q, Barasch J, Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts. Elife. 2017 Jun 3;6:e24265
1	J:292559 Wilhide ME, Feller JD, Li B, Mohamed AZ, Becknell B, Jackson AR, McHugh KM, Ingraham SE, Renal epithelial miR-205 expression correlates with disease severity in a mouse model of congenital obstructive nephropathy. Pediatr Res. 2016 Oct;80(4):602-9
5	J:119674 Yamaguchi Y, Yonemura S, Takada S, Grainyhead-related transcription factor is required for duct maturation in the salivary gland and the kidney of the mouse. Development. 2006 Dec;133(23):4737-48