Gene Expression Literature Summary

• Symbol: Tyro3
• Name: TYRO3 protein tyrosine kinase 3
• ID: MGI:104294

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E10.5	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E17	E17.5	E18.5	E	P
Immunohistochemistry (section)													1		1
In situ RNA (section)		1	2	1	1		2		2		1	2	1		5
Northern blot								1						1	5
Western blot								1							3
RT-PCR						1	1							1	5
cDNA clones	1				1					1					5
RNase protection				1			1								1
Primer Extension															1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tyro3  TYRO3 protein tyrosine kinase 3   (Synonyms: Brt, Dtk, Etk-2, Rse, Sky, Sky, Tif)
Results	Reference
2*	J:13545 Biesecker LG, Gottschalk LR, Emerson SG, Identification of four murine cDNAs encoding putative protein kinases from primitive embryonic stem cells differentiated in vitro. Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7044-8
4*	J:22047 Crosier PS, Lewis PM, Hall LR, Vitas MR, Morris CM, Beier DR, Wood CR, Crosier KE, Isolation of a receptor tyrosine kinase (DTK) from embryonic stem cells: structure, genetic mapping and analysis of expression. Growth Factors. 1994;11(2):125-36
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
6	J:16985 Fujimoto J, Yamamoto T, brt, a mouse gene encoding a novel receptor-type protein-tyrosine kinase, is preferentially expressed in the brain. Oncogene. 1994 Mar;9(3):693-8
2	J:238230 Furlan A, La Manno G, Lubke M, Haring M, Abdo H, Hochgerner H, Kupari J, Usoskin D, Airaksinen MS, Oliver G, Linnarsson S, Ernfors P, Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control. Nat Neurosci. 2016 Oct;19(10):1331-40
1	J:271760 Gobe C, Elzaiat M, Meunier N, Andre M, Sellem E, Congar P, Jouneau L, Allais-Bonnet A, Naciri I, Passet B, Pailhoux E, Pannetier M, Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis. PLoS Genet. 2019 Feb;15(2):e1007909
1*	J:229257 Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y, Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550
5	J:19923 Lai C, Gore M, Lemke G, Structure, expression, and activity of Tyro 3, a neural adhesion-related receptor tyrosine kinase. Oncogene. 1994 Sep;9(9):2567-78
8	J:37337 Matsubara N, Takahashi Y, Nishina Y, Mukouyama Y, Yanagisawa M, Watanabe T, Nakano T, Nomura K, Arita H, Nishimune Y, Obinata M, Matsui Y, A receptor tyrosine kinase, sky, and its ligand gas 6 are expressed in gonads and support primordial germ cell growth or survival in culture. Dev Biol. 1996 DEC 15;180(2):499-510
1	J:269319 Nicol B, Grimm SA, Gruzdev A, Scott GJ, Ray MK, Yao HH, Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads. Hum Mol Genet. 2018 Dec 15;27(24):4273-4287
2	J:141251 Pierce A, Bliesner B, Xu M, Nielsen-Preiss S, Lemke G, Tobet S, Wierman ME, Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. Mol Endocrinol. 2008 Nov;22(11):2481-95
1	J:22208 Ruiz JC, Conlon FL, Robertson EJ, Identification of novel protein kinases expressed in the myocardium of the developing mouse heart. Mech Dev. 1994 Dec;48(3):153-64
2	J:220148 Salian-Mehta S, Xu M, Pierce A, Bliesner B, Tobet S, Wierman ME, Loss of Growth arrest specific gene 6 (Gas6) results in altered GnRH neuron migration, delayed vaginal opening and sexual maturation in mice. Mol Cell Endocrinol. 2014 Aug 5;393(1-2):164-70
1	J:171312 Sammeta N, Hardin DL, McClintock TS, Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium. Mol Cell Neurosci. 2010 Dec;45(4):398-407
5*	J:35581 Sasaki M, Enami J, Structure and expression of a murine homologue of sky receptor tyrosine kinase gene. J Biochem. 1996 Aug;120(2):264-70
1	J:27414 Sommers CL, Huang K, Shores EW, Grinberg A, Charlick DA, Kozak CA, Love PE, Murine txk: a protein tyrosine kinase gene regulated by T cell activation. Oncogene. 1995 Jul 20;11(2):245-51
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
2	J:45303 Tole S, Christian C, Grove EA, Early specification and autonomous development of cortical fields in the mouse hippocampus. Development. 1997 Dec;124(24):4959-70
1	J:316132 Wen Y, Ma X, Wang X, Wang F, Dong J, Wu Y, Lv C, Liu K, Zhang Y, Zhang Z, Yuan S, hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9. Theranostics. 2021;11(20):10030-10046