Gene Expression Literature Summary

• Symbol: Nova1
• Name: NOVA alternative splicing regulator 1
• ID: MGI:104297

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	P
Immunohistochemistry (section)						1				2	2
In situ RNA (section)			3	2	1	2	1	2		1	3
Western blot					1		1				1
RT-PCR	2	1	1		3	2	1	1	1		5
cDNA clones											2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nova1  NOVA alternative splicing regulator 1   (Synonyms: 9430099M15Rik, Nova-1)
Results	Reference
2	J:227642 Giampietro C, Deflorian G, Gallo S, Di Matteo A, Pradella D, Bonomi S, Belloni E, Nyqvist D, Quaranta V, Confalonieri S, Bertalot G, Orsenigo F, Pisati F, Ferrero E, Biamonti G, Fredrickx E, Taveggia C, Wyatt CD, Irimia M, Di Fiore PP, Blencowe BJ, Dejana E, Ghigna C, The alternative splicing factor Nova2 regulates vascular development and lumen formation. Nat Commun. 2015;6:8479
8*	J:183118 Irimia M, Denuc A, Ferran JL, Pernaute B, Puelles L, Roy SW, Garcia-Fernandez J, Marfany G, Evolutionarily conserved A-to-I editing increases protein stability of the alternative splicing factor Nova1. RNA Biol. 2012 Jan 1;9(1):12-21
2	J:234106 Leggere JC, Saito Y, Darnell RB, Tessier-Lavigne M, Junge HJ, Chen Z, NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. Elife. 2016;5:e14264
2	J:251308 Lin JC, Chi YL, Peng HY, Lu YH, RBM4-Nova1-SRSF6 splicing cascade modulates the development of brown adipocytes. Biochim Biophys Acta. 2016 Nov;1859(11):1368-1379
5	J:253164 Lin JC, Lu YH, Liu YR, Lin YJ, RBM4a-regulated splicing cascade modulates the differentiation and metabolic activities of brown adipocytes. Sci Rep. 2016 Feb 9;6:20665
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
4*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
2	J:234107 Saito Y, Miranda-Rottmann S, Ruggiu M, Park CY, Fak JJ, Zhong R, Duncan JS, Fabella BA, Junge HJ, Chen Z, Araya R, Fritzsch B, Hudspeth AJ, Darnell RB, NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Elife. 2016;5:e14371
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1	J:266486 Weyn-Vanhentenryck SM, Feng H, Ustianenko D, Duffie R, Yan Q, Jacko M, Martinez JC, Goodwin M, Zhang X, Hengst U, Lomvardas S, Swanson MS, Zhang C, Precise temporal regulation of alternative splicing during neural development. Nat Commun. 2018 Jun 6;9(1):2189
1*	J:50542 Yang YY, Yin GL, Darnell RB, The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13254-9
2	J:163165 Yano M, Hayakawa-Yano Y, Mele A, Darnell RB, Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Neuron. 2010 Jun 24;66(6):848-58
6	J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168