Gene Expression Literature Summary

• Symbol: Rps6ka3
• Name: ribosomal protein S6 kinase polypeptide 3
• ID: MGI:104557

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17	E17.5	E19.5	E	P
Immunohistochemistry (section)						2								1
In situ RNA (section)		2	1	3	2	1	3	2	2		1	1	1	4
Immunohistochemistry (whole mount)	1
In situ RNA (whole mount)			1
Western blot					1	1		1	1	1				1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Rps6ka3  ribosomal protein S6 kinase polypeptide 3   (Synonyms: Rsk2)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:243001 Cordon-Barris L, Pascual-Guiral S, Yang S, Gimenez-Llort L, Lope-Piedrafita S, Niemeyer C, Claro E, Lizcano JM, Bayascas JR, Mutation of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) substrate-docking site in the developing brain causes microcephaly with abnormal brain morphogenesis independently of Akt, leading to impaired cognition and disruptive behaviors. Mol Cell Biol. 2016 Sep 19;
1*	J:335072 Decourt C, Schaeffer J, Blot B, Paccard A, Excoffier B, Pende M, Nawabi H, Belin S, The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems. PLoS Biol. 2023 Apr;21(4):e3002044
5*	J:166774 Dugani CB, Paquin A, Kaplan DR, Miller FD, Coffin-Lowry syndrome: a role for RSK2 in mammalian neurogenesis. Dev Biol. 2010 Nov 15;347(2):348-59
7*	J:83323 Kohn M, Hameister H, Vogel M, Kehrer-Sawatzki H, Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis. Gene Expr Patterns. 2003 May;3(2):173-7
4	J:211945 Laugel-Haushalter V, Paschaki M, Marangoni P, Pilgram C, Langer A, Kuntz T, Demassue J, Morkmued S, Choquet P, Constantinesco A, Bornert F, Schmittbuhl M, Pannetier S, Viriot L, Hanauer A, Dolle P, Bloch-Zupan A, RSK2 is a modulator of craniofacial development. PLoS One. 2014;9(1):e84343
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:91734 Wang Y, Wang F, Sun T, Trostinskaia A, Wygle D, Puscheck E, Rappolee DA, Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos. Dev Dyn. 2004 Sep;231(1):72-87
1	J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95
10	J:79975 Zeniou M, Ding T, Trivier E, Hanauer A, Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning. Hum Mol Genet. 2002 Nov 1;11(23):2929-40