Gene Expression Literature Summary

• Symbol: Tcf15
• Name: transcription factor 15
• ID: MGI:104664

55 matching records from 55 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1.5	E2	E4.5	E5.5	E6.5	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11.5	E12	E12.5	E14.5	E16.5	E17	E	P
In situ RNA (section)						2	1	2		3		5	1	1	2	1	1		1	1
In situ RNA (whole mount)			1		1	2	2	13	7	16	2	14	1						4
Northern blot																				2
RT-PCR	1	1	1	1	1	1		2		3		1								1
cDNA clones										1		1						1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tcf15  transcription factor 15   (Synonyms: bHLH-EC2, Meso1, paraxis)
Results	Reference
1*	J:106154 Anderson DM, Arredondo J, Hahn K, Valente G, Martin JF, Wilson-Rawls J, Rawls A, Mohawk is a novel homeobox gene expressed in the developing mouse embryo. Dev Dyn. 2006 Mar;235(3):792-801
3*	J:170250 Ando T, Semba K, Suda H, Sei A, Mizuta H, Araki M, Abe K, Imai K, Nakagata N, Araki K, Yamamura K, The floor plate is sufficient for development of the sclerotome and spine without the notochord. Mech Dev. 2011 Jan-Feb;128(1-2):129-40
1	J:142475 Armand AS, Bourajjaj M, Martinez-Martinez S, el Azzouzi H, da Costa Martins PA, Hatzis P, Seidler T, Redondo JM, De Windt LJ, Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis. J Biol Chem. 2008 Oct 24;283(43):29004-10
1	J:132361 Aulehla A, Wiegraebe W, Baubet V, Wahl MB, Deng C, Taketo M, Lewandoski M, Pourquie O, A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation. Nat Cell Biol. 2008 Feb;10(2):186-93
2	J:216520 Beck-Cormier S, Escande M, Souilhol C, Vandormael-Pournin S, Sourice S, Pilet P, Babinet C, Cohen-Tannoudji M, Notchless is required for axial skeleton formation in mice. PLoS One. 2014;9(5):e98507
1*	J:63761 Beckers J, Schlautmann N, Gossler A, The mouse rib-vertebrae mutation disrupts anterior-posterior somite patterning and genetically interacts with a delta1 null allele. Mech Dev. 2000 Jul;95(1-2):35-46
1	J:72325 Bessho Y, Sakata R, Komatsu S, Shiota K, Yamada S, Kageyama R, Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev. 2001 Oct 15;15(20):2642-7
1*	J:125766 Biris KK, Dunty WC Jr, Yamaguchi TP, Mouse Ripply2 is downstream of Wnt3a and is dynamically expressed during somitogenesis. Dev Dyn. 2007 Nov;236(11):3167-72
1*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
14*	J:26515 Blanar MA, Crossley PH, Peters KG, Steingrimsson E, Copeland NG, Jenkins NA, Martin GR, Rutter WJ, Meso1, a basic-helix-loop-helix protein involved in mammalian presomitic mesoderm development. Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5870-4
2	J:121357 Bu P, Evrard YA, Lozano G, Dent SY, Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos. Mol Cell Biol. 2007 May;27(9):3405-16
6*	J:24364 Burgess R, Cserjesi P, Ligon KL, Olson EN, Paraxis: a basic helix-loop-helix protein expressed in paraxial mesoderm and developing somites. Dev Biol. 1995 Apr;168(2):296-306
1	J:90513 Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A, The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev. 2004 May 15;18(10):1209-21
2*	J:239985 Casaca A, Novoa A, Mallo M, Hoxb6 can interfere with somitogenesis in the posterior embryo through a mechanism independent of its rib-promoting activity. Development. 2016 Feb 01;143(3):437-48
1*	J:80954 Chapman DL, Papaioannou VE, Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. Nature. 1998 Feb 12;391(6668):695-7
2	J:139339 Chawengsaksophak K, de Graaff W, Rossant J, Deschamps J, Beck F, Cdx2 is essential for axial elongation in mouse development. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7641-5
2	J:67377 Chung AC, Katz D, Pereira FA, Jackson KJ, DeMayo FJ, Cooney AJ, O'Malley BW, Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Mol Cell Biol. 2001 Jan;21(2):663-77
9*	J:302456 Davies OR, Lin CY, Radzisheuskaya A, Zhou X, Taube J, Blin G, Waterhouse A, Smith AJ, Lowell S, Tcf15 primes pluripotent cells for differentiation. Cell Rep. 2013 Feb 21;3(2):472-84
1	J:42215 Dear TN, Hainzl T, Follo M, Nehls M, Wilmore H, Matena K, Boehm T, Identification of interaction partners for the basic-helix-loop-helix protein E47. Oncogene. 1997 Feb 27;14(8):891-8
1*	J:129202 Dunty WC Jr, Biris KK, Chalamalasetty RB, Taketo MM, Lewandoski M, Yamaguchi TP, Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development. 2008 Jan;135(1):85-94
1*	J:76233 Faisst AM, Alvarez-Bolado G, Treichel D, Gruss P, Rotatin is a novel gene required for axial rotation and left-right specification in mouse embryos. Mech Dev. 2002 Apr;113(1):15-28
2	J:179218 Grainger S, Lam J, Savory JG, Mears AJ, Rijli FM, Lohnes D, Cdx regulates Dll1 in multiple lineages. Dev Biol. 2012 Jan 1;361(1):1-11
1	J:90119 Gregorieff A, Grosschedl R, Clevers H, Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos. EMBO J. 2004 Apr 21;23(8):1825-33
2	J:191565 Grote P, Wittler L, Hendrix D, Koch F, Wahrisch S, Beisaw A, Macura K, Blass G, Kellis M, Werber M, Herrmann BG, The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse. Dev Cell. 2013 Jan 28;24(2):206-14
1	J:145720 Guelman S, Kozuka K, Mao Y, Pham V, Solloway MJ, Wang J, Wu J, Lill JR, Zha J, The double-histone-acetyltransferase complex ATAC is essential for mammalian development. Mol Cell Biol. 2009 Mar;29(5):1176-88
5*	J:54638 Henderson DJ, Conway SJ, Copp AJ, Rib truncations and fusions in the Sp2H mouse reveal a role for Pax3 in specification of the ventro-lateral and posterior parts of the somite. Dev Biol. 1999 May 1;209(1):143-58
1	J:39633 Hrabe de Angelis M, McIntyre J 2nd, Gossler A, Maintenance of somite borders in mice requires the Delta homologue DII1. Nature. 1997 Apr 17;386(6626):717-21
1*	J:122556 Inoue T, Ota M, Mikoshiba K, Aruga J, Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo. Dev Biol. 2007 Jun 15;306(2):669-84
1*	J:67969 Koizumi Ki, Nakajima M, Yuasa S, Saga Y, Sakai T, Kuriyama T, Shirasawa T, Koseki H, The role of presenilin 1 during somite segmentation. Development. 2001 Apr;128(8):1391-402
1*	J:93008 Kokubu C, Heinzmann U, Kokubu T, Sakai N, Kubota T, Kawai M, Wahl MB, Galceran J, Grosschedl R, Ozono K, Imai K, Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis. Development. 2004 Nov;131(21):5469-80
1	J:71693 Kume T, Jiang H, Topczewska JM, Hogan BL, The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis. Genes Dev. 2001 Sep 15;15(18):2470-82
1	J:197427 Lopez TP, Fan CM, Dynamic CREB family activity drives segmentation and posterior polarity specification in mammalian somitogenesis. Proc Natl Acad Sci U S A. 2013 May 28;110(22):E2019-27
1*	J:73506 Lowe LA, Yamada S, Kuehn MR, Genetic dissection of nodal function in patterning the mouse embryo. Development. 2001 May;128(10):1831-43
1	J:84754 Mankoo BS, Skuntz S, Harrigan I, Grigorieva E, Candia A, Wright CV, Arnheiter H, Pachnis V, The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. Development. 2003 Oct;130(19):4655-64
2	J:95326 McDermott A, Gustafsson M, Elsam T, Hui CC, Emerson CP Jr, Borycki AG, Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation. Development. 2005 Jan;132(2):345-57
1*	J:45709 Melloy PG, Ewart JL, Cohen MF, Desmond ME, Kuehn MR, Lo CW, No turning, a mouse mutation causing left-right and axial patterning defects. Dev Biol. 1998 Jan 1;193(1):77-89
1*	J:90276 Ota MS, Loebel DA, O'Rourke MP, Wong N, Tsoi B, Tam PP, Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells. Dev Dyn. 2004 Jun;230(2):216-28
2	J:346126 Pappas MP, Kawakami H, Corcoran D, Chen KQ, Scott EP, Wong J, Gearhart MD, Nishinakamura R, Nakagawa Y, Kawakami Y, Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm. Development. 2024 Mar 1;151(5)
1	J:112181 Petersen PH, Tang H, Zou K, Zhong W, The enigma of the numb-Notch relationship during mammalian embryogenesis. Dev Neurosci. 2006;28(1-2):156-68
1*	J:99573 Phan HM, Xu AW, Coco C, Srajer G, Wyszomierski S, Evrard YA, Eckner R, Dent SY, GCN5 and p300 share essential functions during early embryogenesis. Dev Dyn. 2005 Aug;233(4):1337-47
1	J:42014 Saga Y, Hata N, Koseki H, Taketo MM, Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 1997 Jul 15;11(14):1827-39
1	J:154904 Savory JG, Bouchard N, Pierre V, Rijli FM, De Repentigny Y, Kothary R, Lohnes D, Cdx2 regulation of posterior development through non-Hox targets. Development. 2009 Dec;136(24):4099-110
2*	J:88955 Schwabe GC, Trepczik B, Suring K, Brieske N, Tucker AS, Sharpe PT, Minami Y, Mundlos S, Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome. Dev Dyn. 2004 Feb;229(2):400-10
1	J:202124 Seidl S, Braun U, Roos N, Li S, Ludtke TH, Kispert A, Leitges M, Phenotypical analysis of atypical PKCs in vivo function display a compensatory system at mouse embryonic day 7.5. PLoS One. 2013;8(5):e62756
1*	J:104893 Seo KW, Wang Y, Kokubo H, Kettlewell JR, Zarkower DA, Johnson RL, Targeted disruption of the DM domain containing transcription factor Dmrt2 reveals an essential role in somite patterning. Dev Biol. 2006 Feb 1;290(1):200-10
1*	J:143778 Tamplin OJ, Cox BJ, Rossant J, Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Dev Biol. 2011 Dec 15;360(2):415-25
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
2*	J:330271 Tekko T, Lozovska A, Novoa A, Mallo M, Assessing Myf5 and Lbx1 contribution to carapace development by reproducing their turtle-specific signatures in mouse embryos. Dev Dyn. 2022 Oct;251(10):1698-1710
1*	J:125818 Teppner I, Becker S, de Angelis MH, Gossler A, Beckers J, Compartmentalised expression of Delta-like 1 in epithelial somites is required for the formation of intervertebral joints. BMC Dev Biol. 2007;7:68
2	J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108
1*	J:40308 Wong PC, Zheng H, Chen H, Becher MW, Sirinathsinghji DJ, Trumbauer ME , Chen HY , Price DL , Van der Ploeg LH , Sisodia SS, Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature. 1997 May 15;387(6630):288-92
2	J:65002 Xu W, Edmondson DG, Evrard YA, Wakamiya M, Behringer RR, Roth SY, Loss of gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet. 2000 Oct;26(2):229-32
2*	J:62914 Yoon JK, Moon RT, Wold B, The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes. Dev Biol. 2000 Jun 15;222(2):376-91
1	J:66514 Yoon JK, Wold B, The bHLH regulator pMesogenin1 is required for maturation and segmentation of paraxial mesoderm. Genes Dev. 2000 Dec 15;14(24):3204-14
1	J:154781 Young T, Rowland JE, van de Ven C, Bialecka M, Novoa A, Carapuco M, van Nes J, de Graaff W, Duluc I, Freund JN, Beck F, Mallo M, Deschamps J, Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos. Dev Cell. 2009 Oct;17(4):516-26