Gene Expression Literature Summary

• Symbol: Slc6a5
• Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
• ID: MGI:105090

22 matching records from 22 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E12	E12.5	E13.5	E14	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	P
Immunohistochemistry (section)		1	1	1	1	1		1	1	1	1	1	4
In situ RNA (section)	2		2	1		3	2		2			4	11
In situ reporter (knock in)													1
Western blot			1				1						1
cDNA clones												1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Slc6a5  solute carrier family 6 (neurotransmitter transporter, glycine), member 5   (Synonyms: Glyt2)
Results	Reference
3*	J:23734 Adams RH, Sato K, Shimada S, Tohyama M, Puschel AW, Betz H, Gene structure and glial expression of the glycine transporter GlyT1 in embryonic and adult rodents. J Neurosci. 1995 Mar;15(3 Pt 2):2524-32
1*	J:228503 Altieri SC, Jalabi W, Zhao T, Romito-DiGiacomo RR, Maricich SM, En1 directs superior olivary complex neuron positioning, survival, and expression of FoxP1. Dev Biol. 2015 Dec 1;408(1):99-108
1	J:316641 Altieri SC, Zhao T, Jalabi W, Romito-DiGiacomo RR, Maricich SM, En1 is necessary for survival of neurons in the ventral nuclei of the lateral lemniscus. Dev Neurobiol. 2016 Nov;76(11):1266-1274
1	J:275154 Caldeira V, Dougherty KJ, Borgius L, Kiehn O, Spinal Hb9::Cre-derived excitatory interneurons contribute to rhythm generation in the mouse. Sci Rep. 2017 Jan 27;7:41369
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:104420 Glasgow SM, Henke RM, Macdonald RJ, Wright CV, Johnson JE, Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development. 2005 Dec;132(24):5461-9
1	J:166697 Gray PA, Hayes JA, Ling GY, Llona I, Tupal S, Picardo MC, Ross SE, Hirata T, Corbin JG, Eugenin J, Del Negro CA, Developmental origin of preBotzinger complex respiratory neurons. J Neurosci. 2010 Nov 3;30(44):14883-95
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
5	J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405
7	J:34236 Jursky F, Nelson N, Developmental expression of the glycine transporters GLYT1 and GLYT2 in mouse brain. J Neurochem. 1996 Jul;67(1):336-44
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:270927 Kridsada K, Niu J, Haldipur P, Wang Z, Ding L, Li JJ, Lindgren AG, Herrera E, Thomas GM, Chizhikov VV, Millen KJ, Luo W, Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons. Cell Rep. 2018 Jun 5;23(10):2928-2941
3*	J:321207 Lall D, Armbruster A, Ruffert K, Betz H, Eulenburg V, Transport activities and expression patterns of glycine transporters 1 and 2 in the developing murine brain stem and spinal cord. Biochem Biophys Res Commun. 2012 Jul 13;423(4):661-6
1	J:325444 Lecoin L, Dempsey B, Garancher A, Bourane S, Ruffault PL, Morin-Surun MP, Rocques N, Goulding M, Eychene A, Pouponnot C, Fortin G, Champagnat J, Mafa-dependent GABAergic activity promotes mouse neonatal apneas. Nat Commun. 2022 Jun 7;13(1):3284
1	J:297165 Mona B, Villarreal J, Savage TK, Kollipara RK, Boisvert BE, Johnson JE, Positive autofeedback regulation of Ptf1a transcription generates the levels of PTF1A required to generate itch circuit neurons. Genes Dev. 2020 May 1;34(9-10):621-636
1	J:155932 Rose MF, Ahmad KA, Thaller C, Zoghbi HY, Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22462-7
2	J:156036 Schilling K, Oberdick J, The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Cerebellum. 2009 Dec;8(4):477-89
5	J:243154 Sunagawa M, Shimizu-Okabe C, Kim J, Kobayashi S, Kosaka Y, Yanagawa Y, Matsushita M, Okabe A, Takayama C, Distinct development of the glycinergic terminals in the ventral and dorsal horns of the mouse cervical spinal cord. Neuroscience. 2017 Feb 20;343:459-471
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:282827 Tulloch AJ, Teo S, Carvajal BV, Tessier-Lavigne M, Jaworski A, Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3(Cre) mouse. J Comp Neurol. 2019 Dec 15;527(18):2948-2972
2	J:196947 Wildner H, Das Gupta R, Brohl D, Heppenstall PA, Zeilhofer HU, Birchmeier C, Genome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity. J Neurosci. 2013 Apr 24;33(17):7299-307
1	J:292768 Willett RT, Bayin NS, Lee AS, Krishnamurthy A, Wojcinski A, Lao Z, Stephen D, Rosello-Diez A, Dauber-Decker KL, Orvis GD, Wu Z, Tessier-Lavigne M, Joyner AL, Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth. Elife. 2019 Nov 19;8:e50617