Gene Expression Literature Summary

• Symbol: Efnb2
• Name: ephrin B2
• ID: MGI:105097

237 matching records from 237 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)				3		6	1	4		4		7	2	3	2	5		7		4		3	1	1	10
In situ RNA (section)	1	4	9	13	1	9		13	1	14	4	18	3	20	1	15	3	10	1	1	1	4		4	9
Immunohistochemistry (whole mount)				1																					3
In situ RNA (whole mount)		3	1	8	2	9		1		1		3												3	1
In situ reporter (knock in)	3	5	7	10	2	11	1	5	1	7	1	9	3	10	2	11	2	7	1	6		7		4	18
Northern blot																					1				1
Western blot				2		1				4	1	1		1						1				1	3
RT-PCR		3	4	16		14		4		5	1	6	1	5		6		3		3	1	4		4	14
cDNA clones																								2	1
RNase protection				1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Efnb2  ephrin B2   (Synonyms: ELF-2, Epl5, Eplg5, Htk-L, Lerk5, LERK-5, NLERK-1)
Results	Reference
3	J:67296 Adams RH, Diella F, Hennig S, Helmbacher F, Deutsch U, Klein R, The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell. 2001 Jan 12;104(1):57-69
3	J:53085 Adams RH, Wilkinson GA, Weiss C, Diella F, Gale NW, Deutsch U, Risau W, Klein R, Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev. 1999 Feb 1;13(3):295-306
10	J:240790 Aghajanian H, Cho YK, Manderfield LJ, Herling MR, Gupta M, Ho VC, Li L, Degenhardt K, Aharonov A, Tzahor E, Epstein JA, Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor. Nat Commun. 2016 Jun 30;7:12038
1	J:220960 Akiyama R, Kawakami H, Wong J, Oishi I, Nishinakamura R, Kawakami Y, Sall4-Gli3 system in early limb progenitors is essential for the development of limb skeletal elements. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5075-80
4	J:142774 Alfaro D, Munoz JJ, Garcia-Ceca J, Cejalvo T, Jimenez E, Zapata A, Alterations in the thymocyte phenotype of EphB-deficient mice largely affect the double negative cell compartment. Immunology. 2008 Sep;125(1):131-43
4	J:288357 Arita Y, Nakaoka Y, Matsunaga T, Kidoya H, Yamamizu K, Arima Y, Kataoka-Hashimoto T, Ikeoka K, Yasui T, Masaki T, Yamamoto K, Higuchi K, Park JS, Shirai M, Nishiyama K, Yamagishi H, Otsu K, Kurihara H, Minami T, Yamauchi-Takihara K, Koh GY, Mochizuki N, Takakura N, Sakata Y, Yamashita JK, Komuro I, Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart. Nat Commun. 2014 Jul 29;5:4552
1	J:264380 Artap S, Manderfield LJ, Smith CL, Poleshko A, Aghajanian H, See K, Li L, Jain R, Epstein JA, Endocardial Hippo signaling regulates myocardial growth and cardiogenesis. Dev Biol. 2018 Aug 1;440(1):22-30
1	J:196665 Arvanitis DN, Behar A, Tryoen-Toth P, Bush JO, Jungas T, Vitale N, Davy A, Ephrin B1 maintains apical adhesion of neural progenitors. Development. 2013 May;140(10):2082-92
1	J:128980 Awatramani R, Soriano P, Rodriguez C, Mai JJ, Dymecki SM, Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nat Genet. 2003 Sep;35(1):70-5
5	J:237925 Azizoglu DB, Chong DC, Villasenor A, Magenheim J, Barry DM, Lee S, Marty-Santos L, Fu S, Dor Y, Cleaver O, Vascular development in the vertebrate pancreas. Dev Biol. 2016 Dec 01;420(1):67-78
1*	J:74241 Barbieri AM, Broccoli V, Bovolenta P, Alfano G, Marchitiello A, Mocchetti C, Crippa L, Bulfone A, Marigo V, Ballabio A, Banfi S, Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma. Development. 2002 Feb;129(3):805-13
1	J:125783 Baumer S, Keller L, Holtmann A, Funke R, August B, Gamp A, Wolburg H, Wolburg-Buchholz K, Deutsch U, Vestweber D, Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development. Blood. 2006 Jun 15;107(12):4754-62
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1*	J:152494 Behesti H, Papaioannou VE, Sowden JC, Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. Dev Biol. 2009 Sep 15;333(2):360-72
5	J:221761 Bennett KM, Afanador MD, Lal CV, Xu H, Persad E, Legan SK, Chenaux G, Dellinger M, Savani RC, Dravis C, Henkemeyer M, Schwarz MA, Ephrin-B2 reverse signaling increases alpha5beta1 integrin-mediated fibronectin deposition and reduces distal lung compliance. Am J Respir Cell Mol Biol. 2013 Oct;49(4):680-7
2*	J:191212 Benson MD, Opperman LA, Westerlund J, Fernandez CR, San Miguel S, Henkemeyer M, Chenaux G, Ephrin-B stimulation of calvarial bone formation. Dev Dyn. 2012 Dec;241(12):1901-10
4*	J:28182 Bergemann AD, Cheng HJ, Brambilla R, Klein R, Flanagan JG, ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites. Mol Cell Biol. 1995 Sep;15(9):4921-9
1	J:72325 Bessho Y, Sakata R, Komatsu S, Shiota K, Yamada S, Kageyama R, Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev. 2001 Oct 15;15(20):2642-7
2*	J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41
1	J:315303 Bouche E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH, Reelin induces EphB activation. Cell Res. 2013 Apr;23(4):473-90
1	J:240943 Bruce FM, Brown S, Smith JN, Fuerst PG, Erskine L, DSCAM promotes axon fasciculation and growth in the developing optic pathway. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1702-1707
1	J:90513 Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A, The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev. 2004 May 15;18(10):1209-21
1	J:338402 Cao X, Li T, Xu B, Ding K, Li W, Shen B, Chu M, Zhu D, Rui L, Shang Z, Li X, Wang Y, Zheng S, Alitalo K, Liu G, Tang J, Kubota Y, He Y, Endothelial TIE1 Restricts Angiogenic Sprouting to Coordinate Vein Assembly in Synergy With Its Homologue TIE2. Arterioscler Thromb Vasc Biol. 2023 Aug;43(8):e323-e338
1	J:226411 Caprioli A, Villasenor A, Wylie LA, Braitsch C, Marty-Santos L, Barry D, Karner CM, Fu S, Meadows SM, Carroll TJ, Cleaver O, Wnt4 is essential to normal mammalian lung development. Dev Biol. 2015 Oct 15;406(2):222-34
2	J:161794 Catela C, Kratsios P, Hede M, Lang F, Rosenthal N, Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis. Dev Dyn. 2010 Aug;239(8):2149-60
4	J:267128 Chalothorn D, Faber JE, Formation and maturation of the native cerebral collateral circulation. J Mol Cell Cardiol. 2010 Aug;49(2):251-9
1	J:73073 Chapouton P, Schuurmans C, Guillemot F, Gotz M, The transcription factor neurogenin 2 restricts cell migration from the cortex to the striatum. Development. 2001 Dec;128(24):5149-59
2	J:195489 Chen H, Zhang W, Sun X, Yoshimoto M, Chen Z, Zhu W, Liu J, Shen Y, Yong W, Li D, Zhang J, Lin Y, Li B, Vandusen NJ, Snider P, Schwartz RJ, Conway SJ, Field LJ, Yoder MC, Firulli AB, Carlesso N, Towbin JA, Shou W, Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity. Development. 2013 May;140(9):1946-57
1	J:97008 Chen ZY, Sun C, Reuhl K, Bergemann A, Henkemeyer M, Zhou R, Abnormal hippocampal axon bundling in EphB receptor mutant mice. J Neurosci. 2004 Mar 10;24(10):2366-74
2	J:174608 Chong DC, Koo Y, Xu K, Fu S, Cleaver O, Stepwise arteriovenous fate acquisition during mammalian vasculogenesis. Dev Dyn. 2011 Sep;240(9):2153-65
1	J:198502 Clarke RL, Yzaguirre AD, Yashiro-Ohtani Y, Bondue A, Blanpain C, Pear WS, Speck NA, Keller G, The expression of Sox17 identifies and regulates haemogenic endothelium. Nat Cell Biol. 2013 May;15(5):502-10
3	J:179898 Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW, Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway. Neuron. 2012 Jan 12;73(1):49-63
1	J:163848 Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, Taketo MM, Iruela-Arispe ML, Adams RH, Dejana E, The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev Cell. 2010 Jun 15;18(6):938-49
1	J:206194 Corada M, Orsenigo F, Morini MF, Pitulescu ME, Bhat G, Nyqvist D, Breviario F, Conti V, Briot A, Iruela-Arispe ML, Adams RH, Dejana E, Sox17 is indispensable for acquisition and maintenance of arterial identity. Nat Commun. 2013;4:2609
1	J:229500 Cortegano I, Melgar-Rojas P, Luna-Zurita L, Siguero-Alvarez M, Marcos MA, Gaspar ML, de la Pompa JL, Notch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesis. Cell Death Differ. 2014 Jul;21(7):1081-94
2*	J:62565 Cowan CA, Yokoyama N, Bianchi LM, Henkemeyer M, Fritzsch B, EphB2 guides axons at the midline and is necessary for normal vestibular function. Neuron. 2000 May;26(2):417-30
5	J:91492 Cowan CA, Yokoyama N, Saxena A, Chumley MJ, Silvany RE, Baker LA, Srivastava D, Henkemeyer M, Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Dev Biol. 2004 Jul 15;271(2):263-71
4	J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20
2*	J:194470 Davis RB, Curtis CD, Griffin CT, BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development. Development. 2013 Mar;140(6):1272-81
1	J:115952 Davy A, Bush JO, Soriano P, Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome. PLoS Biol. 2006 Sep;4(10):e315
8	J:143845 Davy A, Soriano P, Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development. Dev Biol. 2007 Apr 1;304(1):182-93
3*	J:78768 De Bellard M, Ching W, Gossler A, Bronner-Fraser M, Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice. Dev Biol. 2002 Sep 1;249(1):121
1	J:330268 De Zoysa P, Toubat O, Harvey DC, Yi C, Liu J, Cavallero S, Hong YK, Sucov HM, Kumar SR, Delta-like ligand-4 regulates Notch-mediated maturation of second heart field progenitor-derived pharyngeal arterial endothelial cells. J Cell Mol Med. 2022 Oct;26(20):5181-5194
3	J:222780 Defourny J, Mateo Sanchez S, Schoonaert L, Robberecht W, Davy A, Nguyen L, Malgrange B, Cochlear supporting cell transdifferentiation and integration into hair cell layers by inhibition of ephrin-B2 signalling. Nat Commun. 2015;6:7017
1	J:178290 del Monte G, Casanova JC, Guadix JA, MacGrogan D, Burch JB, Perez-Pomares JM, de la Pompa JL, Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis. Circ Res. 2011 Apr 1;108(7):824-36
2*	J:124179 Del Monte G, Grego-Bessa J, Gonzalez-Rajal A, Bolos V, De La Pompa JL, Monitoring Notch1 activity in development: Evidence for a feedback regulatory loop. Dev Dyn. 2007 Sep;236(9):2594-614
2	J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445
1	J:198221 Deng Y, Larrivee B, Zhuang ZW, Atri D, Moraes F, Prahst C, Eichmann A, Simons M, Endothelial RAF1/ERK activation regulates arterial morphogenesis. Blood. 2013 May 9;121(19):3988-96, S1-9
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2	J:111207 Dionne MS, Brunet LJ, Eimon PM, Harland RM, Noggin is required for correct guidance of dorsal root ganglion axons. Dev Biol. 2002 Nov 15;251(2):283-93
10*	J:173636 Dravis C, Henkemeyer M, Ephrin-B reverse signaling controls septation events at the embryonic midline through separate tyrosine phosphorylation-independent signaling avenues. Dev Biol. 2011 Jul 1;355(1):138-51
3	J:116671 Dravis C, Wu T, Chumley MJ, Yokoyama N, Wei S, Wu DK, Marcus DC, Henkemeyer M, EphB2 and ephrin-B2 regulate the ionic homeostasis of vestibular endolymph. Hear Res. 2007 Jan;223(1-2):93-104
2	J:91491 Dravis C, Yokoyama N, Chumley MJ, Cowan CA, Silvany RE, Shay J, Baker LA, Henkemeyer M, Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development. Dev Biol. 2004 Jul 15;271(2):272-90
1*	J:93157 Duarte A, Hirashima M, Benedito R, Trindade A, Diniz P, Bekman E, Costa L, Henrique D, Rossant J, Dosage-sensitive requirement for mouse Dll4 in artery development. Genes Dev. 2004 Oct 15;18(20):2474-8
3	J:157054 Egawa G, Osawa M, Uemura A, Miyachi Y, Nishikawa S, Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis. J Invest Dermatol. 2009 Oct;129(10):2386-95
1	J:174966 Erskine L, Reijntjes S, Pratt T, Denti L, Schwarz Q, Vieira JM, Alakakone B, Shewan D, Ruhrberg C, VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm. Neuron. 2011 Jun 9;70(5):951-65
1	J:207512 Escalante A, Murillo B, Morenilla-Palao C, Klar A, Herrera E, Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS. Neuron. 2013 Dec 18;80(6):1392-406
1	J:306225 Ezan J, Moreau MM, Mamo TM, Shimbo M, Decroo M, Richter M, Peyroutou R, Rachel R, Tissir F, de Anda FC, Sans N, Montcouquiol M, Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity. Sci Rep. 2021 Apr 27;11(1):9106
1	J:272744 Fawal MA, Jungas T, Kischel A, Audouard C, Iacovoni JS, Davy A, Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation. Cell Rep. 2018 Jun 5;23(10):2864-2873.e7
2	J:60774 Feng G, Laskowski MB, Feldheim DA, Wang H, Lewis R, Frisen J, Flanagan JG, Sanes JR, Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers. Neuron. 2000 Feb;25(2):295-306
1	J:89444 Fischer A, Schumacher N, Maier M, Sendtner M, Gessler M, The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 2004 Apr 15;18(8):901-11
6	J:115909 Foo SS, Turner CJ, Adams S, Compagni A, Aubyn D, Kogata N, Lindblom P, Shani M, Zicha D, Adams RH, Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell. 2006 Jan 13;124(1):161-73
1	J:162413 Foster KE, Gordon J, Cardenas K, Veiga-Fernandes H, Makinen T, Grigorieva E, Wilkinson DG, Blackburn CC, Richie E, Manley NR, Adams RH, Kioussis D, Coles MC, EphB-ephrin-B2 interactions are required for thymus migration during organogenesis. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13414-9
1	J:183770 Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H, Tbx1 regulates oral epithelial adhesion and palatal development. Hum Mol Genet. 2012 Jun 1;21(11):2524-37
1	J:92247 Furuyama T, Kitayama K, Shimoda Y, Ogawa M, Sone K, Yoshida-Araki K, Hisatsune H, Nishikawa S, Nakayama K, Nakayama K, Ikeda K, Motoyama N, Mori N, Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice. J Biol Chem. 2004 Aug 13;279(33):34741-9
3	J:67371 Gale NW, Baluk P, Pan L, Kwan M, Holash J, DeChiara TM, McDonald DM, Yancopoulos GD, Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells. Dev Biol. 2001 Feb 15;230(2):151-60
3*	J:35772 Gale NW, Flenniken A, Compton DC, Jenkins N, Copeland NG, Gilbert DJ, Davis S, Wilkinson DG, Yancopoulos GD, Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments. Oncogene. 1996 Sep 19;13(6):1343-52
2	J:34329 Gale NW, Holland SJ, Valenzuela DM, Flenniken A, Pan L, Ryan TE, Henkemeyer M, Strebhardt K, Hirai H, Wilkinson DG, Pawson T, Davis S, Yancopoulos GD, Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. Neuron. 1996 Jul;17(1):9-19
1	J:104892 Gammill LS, Gonzalez C, Gu C, Bronner-Fraser M, Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling. Development. 2006 Jan;133(1):99-106
1*	J:160476 Ge C, Stanley P, Effects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes. BMC Dev Biol. 2010;10:36
1	J:106994 Georgakopoulos A, Litterst C, Ghersi E, Baki L, Xu C, Serban G, Robakis NK, Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling. EMBO J. 2006 Mar 22;25(6):1242-52
4*	J:74909 Gerety SS, Anderson DJ, Cardiovascular ephrinB2 function is essential for embryonic angiogenesis. Development. 2002 Mar;129(6):1397-410
1	J:91658 Gitler AD, Lu MM, Epstein JA, PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev Cell. 2004 Jul;7(1):107-16
2	J:70266 Graef IA, Chen F, Chen L, Kuo A, Crabtree GR, Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell. 2001 Jun 29;105(7):863-75
6	J:119151 Grego-Bessa J, Luna-Zurita L, del Monte G, Bolos V, Melgar P, Arandilla A, Garratt AN, Zang H, Mukouyama YS, Chen H, Shou W, Ballestar E, Esteller M, Rojas A, Perez-Pomares JM, de la Pompa JL, Notch signaling is essential for ventricular chamber development. Dev Cell. 2007 Mar;12(3):415-29
1	J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23
3*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:333949 Guo Q, Wang Y, Wang Q, Qian Y, Jiang Y, Dong X, Chen H, Chen X, Liu X, Yu S, Zhu J, Shan S, Wu B, Zhou W, Wang H, In the developing cerebral cortex: axonogenesis, synapse formation, and synaptic plasticity are regulated by SATB2 target genes. Pediatr Res. 2022 Aug 26;
2*	J:131988 Han D, Jeon S, Sohn DH, Lee C, Ahn S, Kim WK, Chung H, Seong RH, SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development. Dev Biol. 2008 Mar 1;315(1):136-46
1	J:253351 Hanley O, Zewdu R, Cohen LJ, Jung H, Lacombe J, Philippidou P, Lee DH, Selleri L, Dasen JS, Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Neuron. 2016 Sep 7;91(5):1005-1020
1	J:224939 Hare LM, Schwarz Q, Wiszniak S, Gurung R, Montgomery KG, Mitchell CA, Phillips WA, Heterozygous expression of the oncogenic Pik3ca(H1047R) mutation during murine development results in fatal embryonic and extraembryonic defects. Dev Biol. 2015 Aug 1;404(1):14-26
1	J:217070 Hatch J, Mukouyama YS, Spatiotemporal mapping of vascularization and innervation in the fetal murine intestine. Dev Dyn. 2015 Jan;244(1):56-68
2	J:335564 He CH, Song NN, Xie PX, Wang YB, Chen JY, Huang Y, Hu L, Li Z, Su JH, Zhang XQ, Zhang L, Ding YQ, Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way. Cell Death Dis. 2023 May 6;14(5):309
1	J:308528 Hernandez Vasquez MN, Ulvmar MH, Gonzalez-Loyola A, Kritikos I, Sun Y, He L, Halin C, Petrova TV, Makinen T, Transcription factor FOXP2 is a flow-induced regulator of collecting lymphatic vessels. EMBO J. 2021 Jun 15;40(12):e107192
1*	J:85445 Herrera E, Brown L, Aruga J, Rachel RA, Dolen G, Mikoshiba K, Brown S, Mason CA, Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57
1	J:94392 Herrera E, Marcus R, Li S, Williams SE, Erskine L, Lai E, Mason C, Foxd1 is required for proper formation of the optic chiasm. Development. 2004 Nov;131(22):5727-39
1	J:143962 High FA, Lu MM, Pear WS, Loomes KM, Kaestner KH, Epstein JA, Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1955-9
1	J:149620 Ho SK, Kovacevic N, Henkelman RM, Boyd A, Pawson T, Henderson JT, EphB2 and EphA4 receptors regulate formation of the principal inter-hemispheric tracts of the mammalian forebrain. Neuroscience. 2009 Jun 2;160(4):784-95
1	J:152840 Hou SC, Chan LW, Chou YC, Su CY, Chen X, Shih YL, Tsai PC, Shen CK, Yan YT, Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis. FEBS Lett. 2009 Sep 3;583(17):2765-71
3	J:149994 Hughes DS, Keynes RJ, Tannahill D, Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation. BMC Dev Biol. 2009;9:30
3	J:255447 Hwa JJ, Beckouche N, Huang L, Kram Y, Lindskog H, Wang RA, Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow. Sci Rep. 2017 Sep 20;7(1):11965
3	J:60835 Imondi R, Wideman C, Kaprielian Z, Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons. Development. 2000 Apr;127(7):1397-410
3	J:162837 Islam S, Loizides AM, Fialkovich JJ, Grand RJ, Montgomery RK, Developmental expression of Eph and ephrin family genes in mammalian small intestine. Dig Dis Sci. 2010 Sep;55(9):2478-88
4*	J:66901 Johnson J, Rhee J, Parsons SM, Brown D, Olson EN, Rawls A, The anterior/posterior polarity of somites is disrupted in paraxis-deficient mice. Dev Biol. 2001 Jan 1;229(1):176-87
1	J:137628 Jones EA, Yuan L, Breant C, Watts RJ, Eichmann A, Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos. Development. 2008 Jul;135(14):2479-88
2	J:144306 Kadison SR, Makinen T, Klein R, Henkemeyer M, Kaprielian Z, EphB receptors and ephrin-B3 regulate axon guidance at the ventral midline of the embryonic mouse spinal cord. J Neurosci. 2006 Aug 30;26(35):8909-14
1	J:173649 Kanady JD, Dellinger MT, Munger SJ, Witte MH, Simon AM, Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax. Dev Biol. 2011 Jun 15;354(2):253-66
2	J:76573 Karam SD, Dottori M, Ogawa K, Henderson JT, Boyd AW, Pasquale EB, Bothwell M, EphA4 is not required for Purkinje cell compartmentation. Brain Res Dev Brain Res. 2002 Apr 30;135(1-2):29-38
2	J:144857 Kim YH, Hu H, Guevara-Gallardo S, Lam MT, Fong SY, Wang RA, Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis. Development. 2008 Nov;135(22):3755-64
6*	J:289438 Kischel A, Audouard C, Fawal MA, Davy A, Ephrin-B2 paces neuronal production in the developing neocortex. BMC Dev Biol. 2020 May 13;20(1):12
2	J:307672 Knupp D, Cooper DA, Saito Y, Darnell RB, Miura P, NOVA2 regulates neural circRNA biogenesis. Nucleic Acids Res. 2021 Jul 9;49(12):6849-6862
2	J:101173 Koo BK, Lim HS, Song R, Yoon MJ, Yoon KJ, Moon JS, Kim YW, Kwon MC, Yoo KW, Kong MP, Lee J, Chitnis AB, Kim CH, Kong YY, Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Development. 2005 Aug;132(15):3459-70
1	J:130369 Koo BK, Yoon MJ, Yoon KJ, Im SK, Kim YY, Kim CH, Suh PG, Jan YN, Kong YY, An obligatory role of mind bomb-1 in notch signaling of Mammalian development. PLoS One. 2007;2(11):e1221
2	J:336410 Koo HY, Kim MA, Min H, Hwang JY, Prajapati-DiNubila M, Kim KS, Matzuk MM, Park JW, Doetzlhofer A, Kim UK, Bok J, Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2213099120
2*	J:99326 Kuhnert F, Campagnolo L, Xiong JW, Lemons D, Fitch MJ, Zou Z, Kiosses WB, Gardner H, Stuhlmann H, Dosage-dependent requirement for mouse Vezf1 in vascular system development. Dev Biol. 2005 Jul 1;283(1):140-156
1	J:68814 Kullander K, Croll SD, Zimmer M, Pan L, McClain J, Hughes V, Zabski S, DeChiara TM, Klein R, Yancopoulos GD, Gale NW, Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control. Genes Dev. 2001 Apr 1;15(7):877-88
2	J:67274 Kullander K, Mather NK, Diella F, Dottori M, Boyd AW, Klein R, Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo. Neuron. 2001 Jan;29(1):73-84
1	J:71693 Kume T, Jiang H, Topczewska JM, Hogan BL, The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis. Genes Dev. 2001 Sep 15;15(18):2470-82
1	J:277244 LaHaye S, Majumdar U, Yasuhara J, Koenig SN, Matos-Nieves A, Kumar R, Garg V, Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation. Dis Model Mech. 2019 Jun 24;12(6):dmm036764
2	J:138814 Lavine KJ, Long F, Choi K, Smith C, Ornitz DM, Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development. Development. 2008 Sep;135(18):3161-71
1	J:194149 Le Bras B, Chatzopoulou E, Heydon K, Martinez S, Ikenaka K, Prestoz L, Spassky N, Zalc B, Thomas JL, Oligodendrocyte development in the embryonic brain: the contribution of the plp lineage. Int J Dev Biol. 2005;49(2-3):209-20
1	J:345473 Lee JG, Yon JM, Kim G, Lee SG, Kim CY, Cheong SA, Kim HY, Yu J, Kim K, Sung YH, Yoo HJ, Woo DC, Rho JK, Ha CH, Pack CG, Oh SH, Lim JS, Han YM, Hong EJ, Seong JK, Lee HW, Lee SW, Lee KU, Kim CJ, Nam SY, Cho YS, Baek IJ, PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development. Nat Commun. 2024 Feb 19;15(1):1487
1	J:127228 Lee JS, Yu Q, Shin JT, Sebzda E, Bertozzi C, Chen M, Mericko P, Stadtfeld M, Zhou D, Cheng L, Graf T, MacRae CA, Lepore JJ, Lo CW, Kahn ML, Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Dev Cell. 2006 Dec;11(6):845-57
3	J:226395 Lewis AE, Hwa J, Wang R, Soriano P, Bush JO, Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Dev Biol. 2015 Oct 15;406(2):186-95
1	J:195048 Li W, Kohara H, Uchida Y, James JM, Soneji K, Cronshaw DG, Zou YR, Nagasawa T, Mukouyama YS, Peripheral nerve-derived CXCL12 and VEGF-A regulate the patterning of arterial vessel branching in developing limb skin. Dev Cell. 2013 Feb 25;24(4):359-71
4*	J:198558 Li W, Mukouyama YS, Tissue-specific venous expression of the EPH family receptor EphB1 in the skin vasculature. Dev Dyn. 2013 Aug;242(8):976-88
1	J:323097 Li-Villarreal N, Wong RLY, Garcia MD, Udan RS, Poche RA, Rasmussen TL, Rhyner AM, Wythe JD, Dickinson ME, FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac. Development. 2022 Apr 1;149(7):dev200131
2	J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274
4	J:208418 Lindskog H, Kim YH, Jelin EB, Kong Y, Guevara-Gallardo S, Kim TN, Wang RA, Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals. Development. 2014 Mar;141(5):1120-8
3	J:216078 Liu J, Dong F, Jeong J, Masuda T, Lobe CG, Constitutively active Notch1 signaling promotes endothelialmesenchymal transition in a conditional transgenic mouse model. Int J Mol Med. 2014 Sep;34(3):669-76
1	J:82686 Liu J, Wilson S, Reh T, BMP receptor 1b is required for axon guidance and cell survival in the developing retina. Dev Biol. 2003 Apr 1;256(1):34-48
2	J:320190 Liu T, Wan RP, Tang LJ, Liu SJ, Li HJ, Zhao QH, Liao WP, Sun XF, Yi YH, Long YS, A MicroRNA Profile in Fmr1 Knockout Mice Reveals MicroRNA Expression Alterations with Possible Roles in Fragile X Syndrome. Mol Neurobiol. 2015;51(3):1053-63
1	J:214959 Lodato S, Molyneaux BJ, Zuccaro E, Goff LA, Chen HH, Yuan W, Meleski A, Takahashi E, Mahony S, Rinn JL, Gifford DK, Arlotta P, Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014 Aug;17(8):1046-54
2*	J:286996 Logan SM, Benson MD, Medial epithelial seam cell migration during palatal fusion. J Cell Physiol. 2020 Feb;235(2):1417-1424
1	J:68850 Lu Q, Sun EE, Klein RS, Flanagan JG, Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell. 2001 Apr 6;105(1):69-79
1	J:126240 Lu X, Le Noble F, Yuan L, Jiang Q, De Lafarge B, Sugiyama D, Breant C, Claes F, De Smet F, Thomas JL, Autiero M, Carmeliet P, Tessier-Lavigne M, Eichmann A, The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature. 2004 Nov 11;432(7014):179-86
1	J:165329 Luna-Zurita L, Prados B, Grego-Bessa J, Luxan G, del Monte G, Benguria A, Adams RH, Perez-Pomares JM, de la Pompa JL, Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. J Clin Invest. 2010 Oct 1;120(10):3493-507
2	J:176643 Luria V, Krawchuk D, Jessell TM, Laufer E, Kania A, Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb. Neuron. 2008 Dec 26;60(6):1039-53
1	J:195070 Luxan G, Casanova JC, Martinez-Poveda B, Prados B, D'Amato G, MacGrogan D, Gonzalez-Rajal A, Dobarro D, Torroja C, Martinez F, Izquierdo-Garcia JL, Fernandez-Friera L, Sabater-Molina M, Kong YY, Pizarro G, Ibanez B, Medrano C, Garcia-Pavia P, Gimeno JR,Monserrat L, Jimenez-Borreguero LJ, de la Pompa JL, Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nat Med. 2013 Feb;19(2):193-201
1*	J:203998 Luxey M, Jungas T, Laussu J, Audouard C, Garces A, Davy A, Eph:ephrin-B1 forward signaling controls fasciculation of sensory and motor axons. Dev Biol. 2013 Nov 15;383(2):264-74
7	J:178362 Luxey M, Laussu J, Jungas T, Davy A, Generation of transgenic mice overexpressing EfnB2 in endothelial cells. Genesis. 2011 Oct;49(10):811-20
1	J:312382 Lyons O, Walker J, Seet C, Ikram M, Kuchta A, Arnold A, Hernandez-Vasquez M, Frye M, Vizcay-Barrena G, Fleck RA, Patel AS, Padayachee S, Mortimer P, Jeffery S, Berland S, Mansour S, Ostergaard P, Makinen T, Modarai B, Saha P, Smith A, Mutations in EPHB4 cause human venous valve aplasia. JCI Insight. 2021 Sep 22;6(18):e140952
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
4	J:95885 Makinen T, Adams RH, Bailey J, Lu Q, Ziemiecki A, Alitalo K, Klein R, Wilkinson GA, PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes Dev. 2005 Feb 1;19(3):397-410
1	J:119936 Manuel M, Georgala PA, Carr CB, Chanas S, Kleinjan DA, Martynoga B, Mason JO, Molinek M, Pinson J, Pratt T, Quinn JC, Simpson TI, Tyas DA, van Heyningen V, West JD, Price DJ, Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization. Development. 2007 Feb;134(3):545-55
1*	J:56427 Manzanares M, Trainor PA, Nonchev S, Ariza-McNaughton L, Brodie J, Gould A, Marshall H, Morrison A, Kwan CT, Sham MH, Wilkinson DG, Krumlauf R, The role of kreisler in segmentation during hindbrain development. Dev Biol. 1999 Jul 15;211(2):220-37
1*	J:37329 Marcus RC, Gale NW, Morrison ME, Mason CA, Yancopoulos GD, Eph family receptors and their ligands distribute in opposing gradients in the developing mouse retina. Dev Biol. 1996 Dec 15;180(2):786-9
1	J:214981 Matsui M, Klingensmith J, Multiple tissue-specific requirements for the BMP antagonist Noggin in development of the mammalian craniofacial skeleton. Dev Biol. 2014 Aug 15;392(2):168-81
1	J:122926 Matsumoto N, Kubo A, Liu H, Akita K, Laub F, Ramirez F, Keller G, Friedman SL, Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6. Blood. 2006 Feb 15;107(4):1357-65
7*	J:284089 Mattiske D, Behringer RR, Overbeek PA, Pask AJ, A novel long non-coding RNA, Leat1, causes reduced anogenital distance and fertility in female mice. Differentiation. 2019 Dec 4;112:1-6
4*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
3	J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92
1	J:333797 Min KW, Kim N, Lee JH, Sung Y, Kim M, Lee EJ, Kim JM, Kim JH, Lee J, Cho W, Yang JM, Kim N, Kim J, Lee CJ, Park YG, Lee SH, Lee HW, Kim JW, Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant. Exp Mol Med. 2023 Feb;55(2):385-400
1	J:108515 Molotkov A, Molotkova N, Duester G, Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning. Development. 2006 May;133(10):1901-10
2	J:89474 Morikawa Y, Cserjesi P, Extra-embryonic vasculature development is regulated by the transcription factor HAND1. Development. 2004 May;131(9):2195-204
1	J:217497 Morioka T, Sakabe M, Ioka T, Iguchi T, Mizuta K, Hattammaru M, Sakai C, Itoh M, Sato GE, Hashimoto A, Fujita M, Okumura K, Araki M, Xin M, Pedersen RA, Utset MF, Kimura H, Nakagawa O, An important role of endothelial hairy-related transcription factors in mouse vascular development. Genesis. 2014 Nov;52(11):897-906
1*	J:74240 Mui SH, Hindges R, O'Leary DD, Lemke G, Bertuzzi S, The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Development. 2002 Feb;129(3):797-804
1	J:183123 Mukouyama YS, James J, Nam J, Uchida Y, Whole-mount confocal microscopy for vascular branching morphogenesis. Methods Mol Biol. 2012;843:69-78
1	J:171526 Murali D, Kawaguchi-Niida M, Deng CX, Furuta Y, Smad4 Is Required Predominantly in the Developmental Processes Dependent on the BMP Branch of the TGF-{beta} Signaling System in the Embryonic Mouse Retina. Invest Ophthalmol Vis Sci. 2011;52(6):2930-7
1	J:226023 Murillo B, Ruiz-Reig N, Herrera M, Fairen A, Herrera E, Zic2 Controls the Migration of Specific Neuronal Populations in the Developing Forebrain. J Neurosci. 2015 Aug 12;35(32):11266-80
1*	J:84418 Nakajima M, Yuasa S, Ueno M, Takakura N, Koseki H, Shirasawa T, Abnormal blood vessel development in mice lacking presenilin-1. Mech Dev. 2003 Jun;120(6):657-67
3	J:241748 Nakamura PA, Hsieh CY, Cramer KS, EphB signaling regulates target innervation in the developing and deafferented auditory brainstem. Dev Neurobiol. 2012 Sep;72(9):1243-55
1	J:194919 Nam J, Onitsuka I, Hatch J, Uchida Y, Ray S, Huang S, Li W, Zang H, Ruiz-Lozano P, Mukouyama YS, Coronary veins determine the pattern of sympathetic innervation in the developing heart. Development. 2013 Apr;140(7):1475-85
1	J:163740 Ni A, Lashnits E, Yao LC, Baluk P, McDonald DM, Rapid remodeling of airway vascular architecture at birth. Dev Dyn. 2010 Sep;239(9):2354-66
1	J:154587 Niquille M, Garel S, Mann F, Hornung JP, Otsmane B, Chevalley S, Parras C, Guillemot F, Gaspar P, Yanagawa Y, Lebrand C, Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol. 2009 Oct;7(10):e1000230
1	J:240082 Noh H, Lee H, Park E, Park S, Proper closure of the optic fissure requires ephrin A5-EphB2-JNK signaling. Development. 2016 Feb 01;143(3):461-72
1	J:355222 Nord C, Jones I, Garcia-Maestre M, Hagglund AC, Carlsson L, Reduced mTORC1-signaling in progenitor cells leads to retinal lamination deficits. Dev Dyn. 2024 Oct;253(10):922-939
1	J:150346 North HA, Zhao X, Kolk SM, Clifford MA, Ziskind DM, Donoghue MJ, Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling. Development. 2009 Jul;136(14):2467-76
1	J:78347 Oike Y, Ito Y, Hamada K, Zhang XQ, Miyata K, Arai F, Inada T, Araki K, Nakagata N, Takeya M, Kisanuki YY, Yanagisawa M, Gale NW, Suda T, Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells. Blood. 2002 Aug 15;100(4):1326-33
2*	J:37095 Orioli D, Henkemeyer M, Lemke G, Klein R, Pawson T, Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 1996 15;15(22):6035-49
1*	J:90276 Ota MS, Loebel DA, O'Rourke MP, Wong N, Tsoi B, Tam PP, Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells. Dev Dyn. 2004 Jun;230(2):216-28
1	J:274877 Padget RL, Mohite SS, Hoog TG, Justis BS, Green BE, Udan RS, Hemodynamic force is required for vascular smooth muscle cell recruitment to blood vessels during mouse embryonic development. Mech Dev. 2019 Apr;156:8-19
2	J:346126 Pappas MP, Kawakami H, Corcoran D, Chen KQ, Scott EP, Wong J, Gearhart MD, Nishinakamura R, Nakagawa Y, Kawakami Y, Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm. Development. 2024 Mar 1;151(5)
4*	J:138785 Passante L, Gaspard N, Degraeve M, Frisen J, Kullander K, De Maertelaer V, Vanderhaeghen P, Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum. Development. 2008 Oct;135(19):3281-90
1*	J:150963 Pavlinkova G, Salbaum JM, Kappen C, Maternal diabetes alters transcriptional programs in the developing embryo. BMC Genomics. 2009;10:274
3	J:309375 Peuckert C, Aresh B, Holenya P, Adams D, Sreedharan S, Porthin A, Andersson L, Pettersson H, Wolfl S, Klein R, Oxburgh L, Kullander K, Multimodal Eph/Ephrin signaling controls several phases of urogenital development. Kidney Int. 2016 Aug;90(2):373-388
4*	J:83513 Pickles JO, Expression of Ephs and ephrins in developing mouse inner ear. Hear Res. 2003 Apr;178(1-2):44-51
1	J:311888 Prados B, Gomez-Apinaniz P, Papoutsi T, Luxan G, Zaffran S, Perez-Pomares JM, de la Pompa JL, Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity. Cell Death Dis. 2018 Mar 14;9(3):399
2*	J:92062 Pratt T, Tian NM, Simpson TI, Mason JO, Price DJ, The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse. Development. 2004 Aug;131(15):3773-84
1	J:276877 Qu X, Harmelink C, Baldwin HS, Tie2 regulates endocardial sprouting and myocardial trabeculation. JCI Insight. 2019 May 21;5
13	J:212428 Raft S, Andrade LR, Shao D, Akiyama H, Henkemeyer M, Wu DK, Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear. Dev Biol. 2014 Jun 1;390(1):51-67
5	J:223566 Raft S, Coate TM, Kelley MW, Crenshaw EB 3rd, Wu DK, Pou3f4-mediated regulation of ephrin-b2 controls temporal bone development in the mouse. PLoS One. 2014;9(10):e109043
5	J:158886 Red-Horse K, Ueno H, Weissman IL, Krasnow MA, Coronary arteries form by developmental reprogramming of venous cells. Nature. 2010 Mar 25;464(7288):549-53
1	J:240455 Ren X, Ustiyan V, Pradhan A, Cai Y, Havrilak JA, Bolte CS, Shannon JM, Kalin TV, Kalinichenko VV, FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells. Circ Res. 2014 Sep 26;115(8):709-20
1*	J:145552 Risley M, Garrod D, Henkemeyer M, McLean W, EphB2 and EphB3 forward signalling are required for palate development. Mech Dev. 2009 Mar-Apr;126(3-4):230-9
2	J:137647 Robert-Moreno A, Guiu J, Ruiz-Herguido C, Lopez ME, Ingles-Esteve J, Riera L, Tipping A, Enver T, Dzierzak E, Gridley T, Espinosa L, Bigas A, Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1. EMBO J. 2008 Jul 9;27(13):1886-95
2*	J:57797 Rogers JH, Ciossek T, Menzel P, Pasquale EB, Eph receptors and ephrins demarcate cerebellar lobules before and during their formation. Mech Dev. 1999 Sep;87(1-2):119-28
1	J:180121 Ruf S, Symmons O, Uslu VV, Dolle D, Hot C, Ettwiller L, Spitz F, Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat Genet. 2011 Apr;43(4):379-86
3	J:309382 Sandireddy R, Cibi DM, Gupta P, Singh A, Tee N, Uemura A, Epstein JA, Singh MK, Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction. JCI Insight. 2019 Aug 22;4(16)
1	J:171375 Senturk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A, Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature. 2011 Apr 21;472(7343):356-60
1*	J:119144 Seo S, Fujita H, Nakano A, Kang M, Duarte A, Kume T, The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development. Dev Biol. 2006 Jun 15;294(2):458-70
1	J:127386 Shawber CJ, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell SA, Borisenko V, Feirt N, Podgrabinska S, Shiraishi K, Chawengsaksophak K, Rossant J, Accili D, Skobe M, Kitajewski J, Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. J Clin Invest. 2007 Nov;117(11):3369-82
3	J:144155 Shin D, Anderson DJ, Isolation of arterial-specific genes by subtractive hybridization reveals molecular heterogeneity among arterial endothelial cells. Dev Dyn. 2005 Aug;233(4):1589-604
1	J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7
1	J:326086 Sinha T, Lammerts van Bueren K, Dickel DE, Zlatanova I, Thomas R, Lizama CO, Xu SM, Zovein AC, Ikegami K, Moskowitz IP, Pollard KS, Pennacchio LA, Black BL, Differential Etv2 threshold requirement for endothelial and erythropoietic development. Cell Rep. 2022 May 31;39(9):110881
3	J:186473 Somekawa S, Imagawa K, Hayashi H, Sakabe M, Ioka T, Sato GE, Inada K, Iwamoto T, Mori T, Uemura S, Nakagawa O, Saito Y, Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12064-9
5	J:318245 Son EJ, Ma JH, Ankamreddy H, Shin JO, Choi JY, Wu DK, Bok J, Conserved role of Sonic Hedgehog in tonotopic organization of the avian basilar papilla and mammalian cochlea. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3746-51
1*	J:68841 Stuckmann I, Weigmann A, Shevchenko A, Mann M, Huttner WB, Ephrin B1 is expressed on neuroepithelial cells in correlation with neocortical neurogenesis. J Neurosci. 2001 Apr 15;21(8):2726-37
6*	J:86844 Takahashi T, Takahashi K, Gerety S, Wang H, Anderson DJ, Daniel TO, Temporally compartmentalized expression of ephrin-B2 during renal glomerular development. J Am Soc Nephrol. 2001 Dec;12(12):2673-82
1	J:63424 Takakura N, Watanabe T, Suenobu S, Yamada Y, Noda T, Ito Y, Satake M, Suda T, A role for hematopoietic stem cells in promoting angiogenesis. Cell. 2000 Jul 21;102(2):199-209
3	J:277380 Telley L, Agirman G, Prados J, Amberg N, Fievre S, Oberst P, Bartolini G, Vitali I, Cadilhac C, Hippenmeyer S, Nguyen L, Dayer A, Jabaudon D, Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. Science. 2019 May 10;364(6440)
3	J:176056 Thakar S, Chenaux G, Henkemeyer M, Critical roles for EphB and ephrin-B bidirectional signalling in retinocollicular mapping. Nat Commun. 2011;2:431
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:337130 Thompson M, Sakabe M, Verba M, Hao J, Meadows SM, Lu QR, Xin M, PRDM16 regulates arterial development and vascular integrity. Front Physiol. 2023;14:1165379
1	J:220957 Tian X, Hu T, Zhang H, He L, Huang X, Liu Q, Yu W, He L, Yang Z, Zhang Z, Zhong TP, Yang X, Yang Z, Yan Y, Baldini A, Sun Y, Lu J, Schwartz RJ, Evans SM, Gittenberger-de Groot AC, Red-Horse K, Zhou B, Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res. 2013 Sep;23(9):1075-90
2	J:232285 Tibboel J, Groenman FA, Selvaratnam J, Wang J, Tseu I, Huang Z, Caniggia I, Luo D, van Tuyl M, Ackerley C, de Jongste JC, Tibboel D, Post M, Hypoxia-inducible factor-1 stimulates postnatal lung development but does not prevent O2-induced alveolar injury. Am J Respir Cell Mol Biol. 2015 Apr;52(4):448-58
4	J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977
6	J:233757 Treffy RW, Collins D, Hoshino N, Ton S, Katsevman GA, Oleksiak M, Runge EM, Cho D, Russo M, Spec A, Gomulka J, Henkemeyer M, Rochlin MW, Ephrin-B/EphB Signaling Is Required for Normal Innervation of Lingual Gustatory Papillae. Dev Neurosci. 2016;38(2):124-38
1	J:138721 Trindade A, Ram Kumar S, Scehnet JS, Lopes-da-Costa L, Becker J, Jiang W, Liu R, Gill PS, Duarte A, Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos. Blood. 2008 Sep 1;112(5):1720-9
1	J:328045 Trinh LT, Osipovich AB, Sampson L, Wong J, Wright CVE, Magnuson MA, Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development. iScience. 2022 Sep 16;25(9):104905
1	J:180170 Triplett JW, Pfeiffenberger C, Yamada J, Stafford BK, Sweeney NT, Litke AM, Sher A, Koulakov AA, Feldheim DA, Competition is a driving force in topographic mapping. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19060-5
2*	J:65521 Urness LD, Sorensen LK, Li DY, Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet. 2000 Nov;26(3):328-31
2	J:161912 van den Akker NM, Caolo V, Wisse LJ, Peters PP, Poelmann RE, Carmeliet P, Molin DG, Gittenberger-de Groot AC, Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling. Cardiovasc Res. 2008 May 1;78(2):366-75
1	J:130159 Van den Akker NM, Winkel LC, Nisancioglu MH, Maas S, Wisse LJ, Armulik A, Poelmann RE, Lie-Venema H, Betsholtz C, Gittenberger-de Groot AC, PDGF-B signaling is important for murine cardiac development: Its role in developing atrioventricular valves, coronaries, and cardiac innervation. Dev Dyn. 2008 Feb;237(2):494-503
4*	J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9
3	J:311813 VanDusen NJ, Casanovas J, Vincentz JW, Firulli BA, Osterwalder M, Lopez-Rios J, Zeller R, Zhou B, Grego-Bessa J, De La Pompa JL, Shou W, Firulli AB, Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium. Cell Rep. 2014 Dec 24;9(6):2071-83
2*	J:109514 Vats KR, Ishwad C, Singla I, Vats A, Ferrell R, Ellis D, Moritz M, Surti U, Jayakar P, Frederick DR, Vats AN, A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33-34. J Am Soc Nephrol. 2006 Apr;17(4):1158-67
1	J:174191 Vernes SC, Oliver PL, Spiteri E, Lockstone HE, Puliyadi R, Taylor JM, Ho J, Mombereau C, Brewer A, Lowy E, Nicod J, Groszer M, Baban D, Sahgal N, Cazier JB, Ragoussis J, Davies KE, Geschwind DH, Fisher SE, Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain. PLoS Genet. 2011 Jul;7(7):e1002145
1*	J:71910 Villa N, Walker L, Lindsell CE, Gasson J, Iruela-Arispe ML, Weinmaster G, Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels. Mech Dev. 2001 Oct;108(1-2):161-4
1	J:222557 Villar-Cervino V, Kappeler C, Nobrega-Pereira S, Henkemeyer M, Rago L, Nieto MA, Marin O, Molecular Mechanisms Controlling the Migration of Striatal Interneurons. J Neurosci. 2015 Jun 10;35(23):8718-29
1	J:166759 Villasenor A, Chong DC, Henkemeyer M, Cleaver O, Epithelial dynamics of pancreatic branching morphogenesis. Development. 2010 Dec;137(24):4295-305
4	J:183871 Villasenor A, Marty-Santos L, Dravis C, Fletcher P, Henkemeyer M, Cleaver O, EphB3 marks delaminating endocrine progenitor cells in the developing pancreas. Dev Dyn. 2012 May;241(5):1008-19
1*	J:181634 Wallgard E, Nitzsche A, Larsson J, Guo X, Dieterich LC, Dimberg A, Olofsson T, Ponten FC, Makinen T, Kalen M, Hellstrom M, Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development. Dev Dyn. 2012 Apr;241(4):770-86
1	J:64018 Wang CC, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F, Tarlinton D, Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera. Dev Biol. 2000 Aug 15;224(2):152-67
6	J:75288 Wang HU, Chen ZF, Anderson DJ, Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell. 1998 May 29;93(5):741-53
1	J:270088 Wang Y, Lu P, Wu B, Morrow BE, Zhou B, NOTCH maintains developmental cardiac gene network through WNT5A. J Mol Cell Cardiol. 2018 Dec;125:98-105
1	J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578
1	J:238549 Warrier S, Nuwayhid S, Sabatino JA, Sugrue KF, Zohn IE, Supt20 is required for development of the axial skeleton. Dev Biol. 2017 Jan 15;421(2):245-257
1	J:304634 Watanabe Y, Seya D, Ihara D, Ishii S, Uemoto T, Kubo A, Arai Y, Isomoto Y, Nakano A, Abe T, Shigeta M, Kawamura T, Saito Y, Ogura T, Nakagawa O, Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription. J Biol Chem. 2020 Dec 18;295(51):17632-17645
4	J:214811 Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A, Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30
7	J:139011 Wilkinson GA, Schittny JC, Reinhardt DP, Klein R, Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity. Dev Dyn. 2008 Aug;237(8):2220-34
6*	J:85573 Williams SE, Mann F, Erskine L, Sakurai T, Wei S, Rossi DJ, Gale NW, Holt CE, Mason CA, Henkemeyer M, Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm. Neuron. 2003 Sep 11;39(6):919-35
1	J:214991 Wu ZQ, Rowe RG, Lim KC, Lin Y, Willis A, Tang Y, Li XY, Nor JE, Maillard I, Weiss SJ, A Snail1/Notch1 signalling axis controls embryonic vascular development. Nat Commun. 2014;5:3998
2	J:297072 Wurmser M, Chaverot N, Madani R, Sakai H, Negroni E, Demignon J, Saint-Pierre B, Mouly V, Amthor H, Tapscott S, Birchmeier C, Tajbakhsh S, Le Grand F, Sotiropoulos A, Maire P, SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis. Development. 2020 Oct 9;147(19):dev185975
4	J:297694 Wythe JD, Dang LT, Devine WP, Boudreau E, Artap ST, He D, Schachterle W, Stainier DY, Oettgen P, Black BL, Bruneau BG, Fish JE, ETS factors regulate Vegf-dependent arterial specification. Dev Cell. 2013 Jul 15;26(1):45-58
4*	J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60
1	J:327590 Xia S, Menden HL, Townley N, Mabry SM, Johnston J, Nyp MF, Heruth DP, Korfhagen T, Sampath V, Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung. JCI Insight. 2021 Apr 8;6(7)
1	J:202407 Xiao Y, Woo WM, Nagao K, Li W, Terunuma A, Mukouyama YS, Oro AE, Vogel JC, Brownell I, Perivascular hair follicle stem cells associate with a venule annulus. J Invest Dermatol. 2013 Oct;133(10):2324-31
1	J:152906 Xie J, Wu T, Xu K, Huang IK, Cleaver O, Huang CL, Endothelial-specific expression of WNK1 kinase is essential for angiogenesis and heart development in mice. Am J Pathol. 2009 Sep;175(3):1315-27
1	J:195852 Xie Q, Yang Y, Huang J, Ninkovic J, Walcher T, Wolf L, Vitenzon A, Zheng D, Gotz M, Beebe DC, Zavadil J, Cvekl A, Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain. PLoS One. 2013;8(1):e54507
2*	J:344941 Yan F, Suzuki A, Iwaya C, Pei G, Chen X, Yoshioka H, Yu M, Simon LM, Iwata J, Zhao Z, Single-cell multiomics decodes regulatory programs for mouse secondary palate development. Nat Commun. 2024 Jan 27;15(1):821
1	J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767
1	J:98247 You LR, Lin FJ, Lee CT, DeMayo FJ, Tsai MJ, Tsai SY, Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature. 2005 May 5;435(7038):98-104
2	J:84008 Yu G, Luo H, Wu Y, Wu J, Ephrin B2 induces T cell costimulation. J Immunol. 2003 Jul 1;171(1):106-14
1*	J:201739 Zhu Q, Kim YH, Wang D, Oh SP, Luo K, SnoN facilitates ALK1-Smad1/5 signaling during embryonic angiogenesis. J Cell Biol. 2013 Sep 16;202(6):937-50
1	J:178901 Zimmer G, Rudolph J, Landmann J, Gerstmann K, Steinecke A, Gampe C, Bolz J, Bidirectional EphrinB3/EphA4 Signaling Mediates the Segregation of Medial Ganglionic Eminence- and Preoptic Area-Derived Interneurons in the Deep and Superficial Migratory Stream. J Neurosci. 2011 Dec 14;31(50):18364-80
2	J:154920 Zirzow S, Ludtke TH, Brons JF, Petry M, Christoffels VM, Kispert A, Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse. Dev Biol. 2009 Dec 15;336(2):145-55