Gene Expression Literature Summary

• Symbol: Pnoc
• Name: prepronociceptin
• ID: MGI:105308

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10	E11.5	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E18	E18.5	E	P
Immunohistochemistry (section)						1				1					1
In situ RNA (section)		2	2	1	2		1	1	3		2	1	3		5
Northern blot	2					2									2
Western blot						1									1
RT-PCR		1					1	1		1			1		2
cDNA clones														1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pnoc  prepronociceptin   (Synonyms: N23K, N/OFQ, Npnc1, OFQ/N, proorphanin)
Results	Reference
2	J:141954 Brohl D, Strehle M, Wende H, Hori K, Bormuth I, Nave KA, Muller T, Birchmeier C, A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord. Dev Biol. 2008 Aug 7;322(2):381-393
4*	J:332212 Cao R, Takechi M, Wang X, Furutera T, Nojiri T, Koyabu D, Li J, Temporal and regulatory dynamics of the inner ear transcriptome during development in mice. Sci Rep. 2022 Dec 7;12(1):21196
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
5	J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405
4	J:49268 Ikeda K, Watanabe M, Ichikawa T, Kobayashi T, Yano R, Kumanishi T, Distribution of prepro-nociceptin/orphanin FQ mRNA and its receptor mRNA in developing and adult mouse central nervous systems. J Comp Neurol. 1998 Sep 14;399(1):139-51
1	J:332369 Liau ES, Jin S, Chen YC, Liu WS, Calon M, Nedelec S, Nie Q, Chen JA, Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons. Nat Commun. 2023 Jan 3;14(1):46
1*	J:270210 Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ, Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:205051 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Sestan N, Gage FH, Lein ES, Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
1	J:305279 Morello F, Borshagovski D, Survila M, Tikker L, Sadik-Ogli S, Kirjavainen A, Estartus N, Knaapi L, Lahti L, Toronen P, Mazutis L, Delogu A, Salminen M, Achim K, Partanen J, Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain. Cell Rep. 2020 Oct 13;33(2):108268
1	J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425
8	J:33720 Saito Y, Maruyama K, Kawano H, Hagino-Yamagishi K, Kawamura K, Saido TC, Kawashima S, Molecular cloning and characterization of a novel form of neuropeptide gene as a developmentally regulated molecule. J Biol Chem. 1996 Jun 28;271(26):15615-22
3*	J:30116 Saito Y, Maruyama K, Saido TC, Kawashima S, N23K, a gene transiently up-regulated during neural differentiation, encodes a precursor protein for a newly identified neuropeptide nociceptin. Biochem Biophys Res Commun. 1995 Dec 14;217(2):539-45
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23