Gene Expression Literature Summary

• Symbol: Hspa8
• Name: heat shock protein 8
• ID: MGI:105384

29 matching records from 29 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E7.5	E8.5	E9.5	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)								1		1		2		1		2									2
In situ RNA (section)							1			2	1	1	1	2	1		1	1	1			2			1
Northern blot				1		1				1		1	1	1						1					1
Western blot	1	2		3	3	3		4		3		4		2		1		1		3	1	1		1	8
RT-PCR	1	1				1		1	1	2	1	1		1	1	1			1				1		3
cDNA clones			1					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hspa8  heat shock protein 8   (Synonyms: 2410008N15Rik, Hsc70, Hsc71, Hsc73, Hsp73)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
2*	J:236179 Bowman CE, Zhao L, Hartung T, Wolfgang MJ, Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series. Mol Cell Biol. 2016 Aug 1;36(15):2089-104
1	J:304329 Chen D, He F, Lu T, Huang J, Li M, Cai D, Huang C, Chen D, Xiong F, VPS4B deficiency causes early embryonic lethality and induces signal transduction disorders of cell endocytosis. Genesis. 2021 Mar 7;:e23415
1	J:235155 Doucet-Beaupre H, Gilbert C, Profes MS, Chabrat A, Pacelli C, Giguere N, Rioux V, Charest J, Deng Q, Laguna A, Ericson J, Perlmann T, Ang SL, Cicchetti F, Parent M, Trudeau LE, Levesque M, Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4387-96
8*	J:74044 Eriksson M, Jokinen E, Sistonen L, Leppa S, Heat shock factor 2 is activated during mouse heart development. Int J Dev Biol. 2000 Aug;44(5):471-7
3*	J:17982 Giebel LB, Dworniczak BP, Bautz EK, Developmental regulation of a constitutively expressed mouse mRNA encoding a 72-kDa heat shock-like protein. Dev Biol. 1988 Jan;125(1):200-7
16*	J:45236 Hatayama T, Takigawa T, Takeuchi S, Shiota K, Characteristic expression of high molecular mass heat shock protein HSP105 during mouse embryo development. Cell Struct Funct. 1997 Oct;22(5):517-25
1	J:50869 Ko MSH, Threat TA, Wang X, Horton JH, Cui Y, Pryor E, Paris J , Wells-Smith J , Kitchen JR , Rowe LB , Eppig J , Satoh T , Brant L , Fujiwara H , Yotsumoto S , Nakashima H, Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
3	J:91328 Liu CH, Yang CC, Lin DP, Wu MH, Tsai KJ, Stored of Hsp72/Hsp73 in germinal vesicle-stage mouse oocytes. Reprod Domest Anim. 2004 Feb;39(1):19-24
1	J:82199 Liu Y, Hogan BL, Differential gene expression in the distal tip endoderm of the embryonic mouse lung. Gene Expr Patterns. 2002 Dec;2(3-4):229-33
1*	J:52895 Loones MT, Morange M, Hsp and chaperone distribution during endochondral bone development in mouse embryo. Cell Stress Chaperones. 1998 Dec;3(4):237-44
3	J:334501 Maglica M, Kelam N, Haque E, Perutina I, Racetin A, Filipovic N, Katsuyama Y, Vukojevic K, Immunoexpression Pattern of Autophagy Markers in Developing and Postnatal Kidneys of Dab1(-/-)(yotari) Mice. Biomolecules. 2023 Feb 21;13(3)
1*	J:35220 Manejwala FM, Logan CY, Schultz RM, Regulation of hsp70 mRNA levels during oocyte maturation and zygotic gene activation in the mouse [published erratum appears in Dev Biol 1991 Nov;148(1):402]. Dev Biol. 1991 Apr;144(2):301-8
2*	J:338888 Martinez-Garza U, Choi J, Scafidi S, Wolfgang MJ, Proteomics identifies the developmental regulation of HKDC1 in liver of pigs and mice. Am J Physiol Regul Integr Comp Physiol. 2023 Aug 7;
2*	J:307963 Mrowiec K, Chadalski M, Paszek A, Vydra N, Janus P, Pietrowska M, Toma-Jonik A, Gramatyka M, Widlak W, The periphilin 1-like BFAR isoform 3 is highly expressed in transcriptionally silent oocytes and involved in RNA metabolism. Biochim Biophys Acta Mol Cell Res. 2021 Sep;1868(10):119086
2	J:192764 Ngalame NN, Micciche AF, Feil ME, States JC, Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure. Toxicol Sci. 2013 Jan;131(1):225-33
2	J:305082 Pathak P, Blech-Hermoni Y, Subedi K, Mpamugo J, Obeng-Nyarko C, Ohman R, Molloy I, Kates M, Hale J, Stauffer S, Sharan SK, Mankodi A, Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCalpha and TSC2-mTOR downregulation. Commun Biol. 2021 Mar 19;4(1):355
1*	J:39331 Rallu M, Loones M, Lallemand Y, Morimoto R, Morange M, Mezger V, Function and regulation of heat shock factor 2 during mouse embryogenesis. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2392-7
2	J:103331 Ryu J, Vicencio AG, Yeager ME, Kashgarian M, Haddad GG, Eickelberg O, Differential expression of matrix metalloproteinases and their inhibitors in human and mouse lung development. Thromb Haemost. 2005 Jul;94(1):175-83
2	J:140797 Snow AJ, Puri P, Acker-Palmer A, Bouwmeester T, Vijayaraghavan S, Kline D, Phosphorylation-dependent interaction of tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein (YWHA) with PADI6 following oocyte maturation in mice. Biol Reprod. 2008 Aug;79(2):337-47
1	J:344338 Subramanian M, Mills WT 4th, Paranjpe MD, Onuchukwu US, Inamdar M, Maytin AR, Li X, Pomerantz JL, Meffert MK, Growth-suppressor microRNAs mediate synaptic overgrowth and behavioral deficits in Fragile X mental retardation protein deficiency. iScience. 2024 Jan 19;27(1):108676
7*	J:31372 Tanaka Y, Kobayashi K, Kita M, Kinoshita S, Imanishi J, Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33
1	J:153804 Vijayaraj P, Kroger C, Reuter U, Windoffer R, Leube RE, Magin TM, Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor. J Cell Biol. 2009 Oct 19;187(2):175-84
8*	J:81589 Wada H, Kobayashi I, Yamaza H, Matsuo K, Kiyoshima T, Akhtar M, Sakai T, Koyano K, Sakai H, In situ expression of heat shock proteins, Hsc73, Hsj2 and Hsp86 in the developing tooth germ of mouse lower first molar. Histochem J. 2002 Mar-Apr;34(3-4):105-9
4*	J:83730 Wang G, Zhang J, Moskophidis D, Mivechi NF, Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis. Genesis. 2003 May;36(1):48-61
6	J:109496 Wilhelm D, Huang E, Svingen T, Stanfield S, Dinnis D, Koopman P, Comparative proteomic analysis to study molecular events during gonad development in mice. Genesis. 2006 Apr;44(4):168-76
3	J:58383 Xiao X, Zuo X, Davis AA, McMillan DR, Curry BB, Richardson JA, Benjamin IJ, HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice. EMBO J. 1999 Nov 1;18(21):5943-52
2*	J:74152 Yamaza H, Matsuo K, Kiyoshima T, Shigemura N, Kobayashi I, Wada H, Akamime A, Sakai H, Detection of differentially expressed genes in the early developmental stage of the mouse mandible. Int J Dev Biol. 2001 Jun;45(4):675-80
5	J:126896 Yildirim AO, Bulau P, Zakrzewicz D, Kitowska KE, Weissmann N, Grimminger F, Morty RE, Eickelberg O, Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases. Am J Respir Cell Mol Biol. 2006 Oct;35(4):436-43