Symbol Name ID |
Anxa5
annexin A5 MGI:106008 |
Age | E5.5 | E7 | E7.5 | E8.5 | E9 | E9.5 | E10.5 | E11 | E11.5 | E12.5 | E13 | E13.5 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 7 | |||||||||
In situ RNA (section) | 2 | 3 | 1 | 1 | ||||||||||||||||
Immunohistochemistry (whole mount) | 1 | |||||||||||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | ||||||||||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | |||||||||
Western blot | 1 | 1 | 1 | 1 | ||||||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 |
Anxa5 annexin A5 (Synonyms: annexin V, Anx5) | |
Results | Reference |
1 | J:167536 Abbas HA, Maccio DR, Coskun S, Jackson JG, Hazen AL, Sills TM, You MJ, Hirschi KK, Lozano G, Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity. Cell Stem Cell. 2010 Nov 5;7(5):606-17 |
1* | J:325730 Ahuja N, Hiltabidle MS, Rajasekhar H, Voss S, Lu SZ, Barlow HR, Cowdin MA, Daniel E, Vaddaraju V, Anandakumar T, Black E, Cleaver O, Maynard C, Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95 |
1 | J:186357 Baleriola J, Suarez T, de la Rosa EJ, DNA-PK promotes the survival of young neurons in the embryonic mouse retina. Cell Death Differ. 2010 Nov;17(11):1697-706 |
1 | J:346054 Baur K, Carrillo-Garcia C, San S, von Hahn M, Strelau J, Holzl-Wenig G, Mandl C, Ciccolini F, Growth/differentiation factor 15 controls ependymal and stem cell number in the V-SVZ. Stem Cell Reports. 2024 Mar 12;19(3):351-365 |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
10 | J:98505 Brachvogel B, Moch H, Pausch F, Schlotzer-Schrehardt U, Hofmann C, Hallmann R, von der Mark K, Winkler T, Poschl E, Perivascular cells expressing annexin A5 define a novel mesenchymal stem cell-like population with the capacity to differentiate into multiple mesenchymal lineages. Development. 2005 Jun;132(11):2657-68 |
10* | J:73299 Brachvogel B, Welzel H, Moch H, von der Mark K, Hofmann C, Poschl E, Sequential expression of annexin A5 in the vasculature and skeletal elements during mouse development. Mech Dev. 2001 Dec;109(2):389-93 |
1 | J:56509 Carmeliet P, Lampugnani MG, Moons L, Breviario F, Compernolle V, Bono F, Balconi G, Spagnuolo R, Oostuyse B, Dewerchin M, Zanetti A, Angellilo A, Mattot V, Nuyens D, Lutgens E, Clotman F, de Ruiter MC, Gittenberger-de Groot A, Poelmann R, Lupu F, HerbertJM, Collen D, Dejana E, Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell. 1999 Jul 23;98(2):147-57 |
1 | J:333323 Chen H, Bai Y, Kobayashi M, Xiao S, Cai W, Barajas S, Chen S, Miao J, Meke FN, Vemula S, Ropa JP, Croop JM, Boswell HS, Wan J, Jia Y, Liu H, Li LS, Altman JK, Eklund EA, Ji P, Tong W, Band H, Huang DT, Platanias LC, Zhang ZY, Liu Y, PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371. Blood. 2023 Jan 19;141(3):244-259 |
6* | J:35723 Chepenik KP, Shipman-Appasamy P, Ahn N, Goldowitz D, Developmental regulation of various annexins in the embryonic palate of the mouse: dexamethasone affects expression of annexin-1. J Craniofac Genet Dev Biol. 1995 Oct-Dec;15(4):171-81 |
1 | J:329269 Cserep C, Schwarcz AD, Posfai B, Laszlo ZI, Kellermayer A, Kornyei Z, Kisfali M, Nyerges M, Lele Z, Katona I, Adam Denes, Microglial control of neuronal development via somatic purinergic junctions. Cell Rep. 2022 Sep 20;40(12):111369 |
1 | J:188796 de Lau W, Kujala P, Schneeberger K, Middendorp S, Li VS, Barker N, Martens A, Hofhuis F, DeKoter RP, Peters PJ, Nieuwenhuis E, Clevers H, Peyer's patch M cells derived from Lgr5(+) stem cells require SpiB and are induced by RankL in cultured "miniguts". Mol Cell Biol. 2012 Sep;32(18):3639-47 |
1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
3* | J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998; |
1 | J:217593 Garcia TX, Farmaha JK, Kow S, Hofmann MC, RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche. Development. 2014 Dec;141(23):4468-78 |
1 | J:204639 Hyde BB, Liesa M, Elorza AA, Qiu W, Haigh SE, Richey L, Mikkola HK, Schlaeger TM, Shirihai OS, The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo. Cell Death Differ. 2012 Jul;19(7):1117-26 |
1 | J:76942 Kallio M, Chang Y, Manuel M, Alastalo TP, Rallu M, Gitton Y, Pirkkala L, Loones MT, Paslaru L, Larney S, Hiard S, Morange M, Sistonen L, Mezger V, Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice. EMBO J. 2002 Jun 3;21(11):2591-601 |
1 | J:187649 Kanaya T, Hase K, Takahashi D, Fukuda S, Hoshino K, Sasaki I, Hemmi H, Knoop KA, Kumar N, Sato M, Katsuno T, Yokosuka O, Toyooka K, Nakai K, Sakamoto A, Kitahara Y, Jinnohara T, McSorley SJ, Kaisho T, Williams IR, Ohno H, The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells. Nat Immunol. 2012;13(8):729-36 |
3 | J:170178 Kobayashi K, Umezawa K, Yasui M, Apoptosis in mouse amniotic epithelium is induced by activated macrophages through the TNF receptor type 1/TNF pathway. Biol Reprod. 2011 Feb;84(2):248-54 |
3* | J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86 |
1 | J:191589 Nishimura R, Wakabayashi M, Hata K, Matsubara T, Honma S, Wakisaka S, Kiyonari H, Shioi G, Yamaguchi A, Tsumaki N, Akiyama H, Yoneda T, Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification. J Biol Chem. 2012 Sep 28;287(40):33179-90 |
2* | J:89190 Poschl E, Schlotzer-Schrehardt U, Brachvogel B, Saito K, Ninomiya Y, Mayer U, Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development. Development. 2004 Apr;131(7):1619-28 |
2* | J:147982 Sehic A, Khuu C, Risnes S, Osmundsen H, Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse. Eur J Oral Sci. 2009 Apr;117(2):93-104 |
2* | J:261957 Svandova EB, Vesela B, Lesot H, Poliard A, Matalova E, Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination. Histochem Cell Biol. 2017 Apr;147(4):497-510 |
2* | J:141291 Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H, Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511 |
2 | J:206109 Ueki H, Mizushina T, Laoharatchatathanin T, Terashima R, Nishimura Y, Rieanrakwong D, Yonezawa T, Kurusu S, Hasegawa Y, Brachvogel B, Poschl E, Kawaminami M, Loss of maternal annexin A5 increases the likelihood of placental platelet thrombosis and foetal loss. Sci Rep. 2012;2:827 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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