Gene Expression Literature Summary

• Symbol: St8sia2
• Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
• ID: MGI:106020

11 matching records from 11 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E17	E18	E20	E	P
In situ RNA (section)	1	1		1		1	1	1		1		1		1	1	1					2
Northern blot	1			1		1						3		1			1	1	2		4
RT-PCR	1		1		1	1	1		2		3		4	1	2		1				4
cDNA clones																				1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

St8sia2  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2   (Synonyms: Siat8b, ST8SiaII)
Results	Reference
4*	J:28219 Kojima N, Yoshida Y, Kurosawa N, Lee YC, Tsuji S, Enzymatic activity of a developmentally regulated member of the sialyltransferase family (STX): evidence for alpha 2,8-sialyltransferase activity toward N-linked oligosaccharides. FEBS Lett. 1995 Feb 20;360(1):1-4
2	J:320531 Kucukerden M, Schuster UE, Rockle I, Alvarez-Bolado G, Schwabe K, Hildebrandt H, Compromised mammillary body connectivity and psychotic symptoms in mice with di- and mesencephalic ablation of ST8SIA2. Transl Psychiatry. 2022 Feb 3;12(1):51
7*	J:41787 Kurosawa N, Yoshida Y, Kojima N, Tsuji S, Polysialic acid synthase (ST8Sia II/STX) mRNA expression in the developing mouse central nervous system. J Neurochem. 1997 Aug;69(2):494-503
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
16*	J:47237 Ong E, Nakayama J, Angata K, Reyes L, Katsuyama T, Arai Y, Fukuda M, Developmental regulation of polysialic acid synthesis in mouse directed by two polysialyltransferases, PST and STX. Glycobiology. 1998 Apr;8(4):415-24
7	J:152222 Schiff M, Weinhold B, Grothe C, Hildebrandt H, NCAM and polysialyltransferase profiles match dopaminergic marker gene expression but polysialic acid is dispensable for development of the midbrain dopamine system. J Neurochem. 2009 Sep;110(5):1661-73
1	J:287871 Schuster UE, Rossdam C, Rockle I, Schiff M, Hildebrandt H, Cell-autonomous impact of polysialic acid-producing enzyme ST8SIA2 on developmental migration and distribution of cortical interneurons. J Neurochem. 2020 Feb;152(3):333-349
2	J:190524 Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, Xu J, Sadovsky Y, Barak Y, Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
2*	J:55849 Takashima S, Tachida Y, Nakagawa T, Hamamoto T, Tsuji S, Quantitative analysis of expression of mouse sialyltransferase genes by competitive PCR. Biochem Biophys Res Commun. 1999 Jun 24;260(1):23-7
4	J:292644 Whiley PAF, O'Donnell L, Moody SC, Handelsman DJ, Young JC, Richards EA, Almstrup K, Western PS, Loveland KL, Activin A Determines Steroid Levels and Composition in the Fetal Testis. Endocrinology. 2020 Jul 1;161(7)
3*	J:26814 Yoshida Y, Kojima N, Kurosawa N, Hamamoto T, Tsuji S, Molecular cloning of Sia alpha 2,3Gal beta 1,4GlcNAc alpha 2,8-sialyltransferase from mouse brain. J Biol Chem. 1995 Jun 16;270(24):14628-33