Gene Expression Literature Summary

• Symbol: Ccr2
• Name: C-C motif chemokine receptor 2
• ID: MGI:106185

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E16	E16.5	E17.5	E18.5	P
Immunohistochemistry (section)						1	1	1						1	1
In situ RNA (section)				1		1				1
In situ reporter (knock in)	1	1	1	1	1	1	1	1				1			1
RT-PCR				1					1		1		1	2	5
RNase protection	1					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ccr2  C-C motif chemokine receptor 2   (Synonyms: CC-CKR-2, CCR2A, CCR2B, CKR2, CKR2A, CKR2B, Cmkbr2)
Results	Reference
2	J:343446 Chen HJ, Galley JD, Verosky BG, Yang FT, Rajasekera TA, Bailey MT, Gur TL, Fetal CCL2 signaling mediates offspring social behavior and recapitulates effects of prenatal stress. Brain Behav Immun. 2024 Jan;115:308-318
2	J:324684 Dang Y, Souchet C, Moresi F, Jeljeli M, Raquillet B, Nicco C, Chouzenoux S, Lagoutte I, Marcellin L, Batteux F, Doridot L, BCG-trained innate immunity leads to fetal growth restriction by altering immune cell profile in the mouse developing placenta. J Leukoc Biol. 2022 May;111(5):1009-1020
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1	J:334094 Gu X, Heinrich A, Li SY, DeFalco T, Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions. Nat Commun. 2023 Mar 15;14(1):1439
1	J:277787 Ikuta K, Fukuda A, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Tsuda M, Kimura Y, Matsumoto Y, Kimura Y, Maruno T, Kanda K, Nishi K, Takaori K, Uemoto S, Takaishi S, Chiba T, Nishi E, Seno H, Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice. Gut. 2019 May;68(5):882-892
3	J:257184 Leid J, Carrelha J, Boukarabila H, Epelman S, Jacobsen SE, Lavine KJ, Primitive Embryonic Macrophages are Required for Coronary Development and Maturation. Circ Res. 2016 May 13;118(10):1498-511
2	J:101029 Lieberam I, Agalliu D, Nagasawa T, Ericson J, Jessell TM, A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons. Neuron. 2005 Sep 1;47(5):667-79
1	J:309498 Liu J, Xue Y, Dong D, Xiao C, Lin C, Wang H, Song F, Fu T, Wang Z, Chen J, Pan H, Li Y, Cai D, Li Z, CCR2(-) and CCR2(+) corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion. Mucosal Immunol. 2017 Sep;10(5):1145-1159
4	J:187608 Longobardi L, Li T, Myers TJ, O'Rear L, Ozkan H, Li Y, Contaldo C, Spagnoli A, TGF-beta type II receptor/MCP-5 axis: at the crossroad between joint and growth plate development. Dev Cell. 2012 Jul 17;23(1):71-81
2*	J:57676 McGrath KE, Koniski AD, Maltby KM, McGann JK, Palis J, Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4. Dev Biol. 1999 Sep 15;213(2):442-56
7	J:180400 Mizutani M, Pino PA, Saederup N, Charo IF, Ransohoff RM, Cardona AE, The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood. J Immunol. 2012 Jan 1;188(1):29-36
1	J:305421 Rosin JM, Sinha S, Biernaskie J, Kurrasch DM, A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors. Dev Cell. 2021 May 3;56(9):1326-1345.e6
1	J:229029 Yamamoto K, Miki Y, Sato M, Taketomi Y, Nishito Y, Taya C, Muramatsu K, Ikeda K, Nakanishi H, Taguchi R, Kambe N, Kabashima K, Lambeau G, Gelb MH, Murakami M, The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasia. J Exp Med. 2015 Oct 19;212(11):1901-19
1	J:312414 Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K, Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. Commun Biol. 2021 Oct 20;4(1):1204