Gene Expression Literature Summary

• Symbol: Hells
• Name: helicase, lymphoid specific
• ID: MGI:106209

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)															1		1
In situ RNA (section)				1			1	1			1			1			2
In situ RNA (whole mount)	1	1		1		1		1
In situ reporter (knock in)																	2
Northern blot						1		2	1	1							3
Western blot				1					1				1		1		3
RT-PCR	1		1	1	1		1		2		1	1	1	1		1	4
cDNA clones									1								1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hells  helicase, lymphoid specific   (Synonyms: E130115I21Rik, LSH, Lysh, PASG, proliferation-associated SNF2-like, YFK8)
Results	Reference
4*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
4*	J:61948 Geiman TM, Muegge K, Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4772-7
4	J:76112 Geiman TM, Tessarollo L, Anver MR, Kopp JB, Ward JM, Muegge K, Lsh, a SNF2 family member, is required for normal murine development. Biochim Biophys Acta. 2001 May 3;1526(2):211-20
1	J:275323 Han Y, Ren J, Lee E, Xu X, Yu W, Muegge K, Lsh/HELLS regulates self-renewal/proliferation of neural stem/progenitor cells. Sci Rep. 2017 Apr 25;7(1):1136
10*	J:32111 Jarvis CD, Geiman T, Vila-Storm MP, Osipovich O, Akella U, Candeias S, Nathan I, Durum SK, Muegge K, A novel putative helicase produced in early murine lymphocytes. Gene. 1996 Mar 9;169(2):203-7
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:282593 Norrie JL, Lupo MS, Xu B, Al Diri I, Valentine M, Putnam D, Griffiths L, Zhang J, Johnson D, Easton J, Shao Y, Honnell V, Frase S, Miller S, Stewart V, Zhou X, Chen X, Dyer MA, Nucleome Dynamics during Retinal Development. Neuron. 2019 Nov 6;104(3):512-528.e11
2	J:183999 Ouseph MM, Li J, Chen HZ, Pecot T, Wenzel P, Thompson JC, Comstock G, Chokshi V, Byrne M, Forde B, Chong JL, Huang K, Machiraju R, de Bruin A, Leone G, Atypical E2F repressors and activators coordinate placental development. Dev Cell. 2012 Apr 17;22(4):849-62
10	J:69100 Raabe EH, Abdurrahman L, Behbehani G, Arceci RJ, An SNF2 factor involved in mammalian development and cellular proliferation. Dev Dyn. 2001 May;221(1):92-105
3	J:107145 Sun LQ, Lee DW, Zhang Q, Xiao W, Raabe EH, Meeker A, Miao D, Huso DL, Arceci RJ, Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG. Genes Dev. 2004 May 1;18(9):1035-46
1*	J:160567 Velasco G, Hube F, Rollin J, Neuillet D, Philippe C, Bouzinba-Segard H, Galvani A, Viegas-Pequignot E, Francastel C, Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9281-6
2	J:345314 Vukic M, Chouaref J, Della Chiara V, Dogan S, Ratner F, Hogenboom JZM, Epp TA, Chawengsaksophak K, Vonk KKD, Breukel C, Ariyurek Y, San Leon Granado D, Kloet SL, Daxinger L, CDCA7-associated global aberrant DNA hypomethylation translates to localized, tissue-specific transcriptional responses. Sci Adv. 2024 Feb 9;10(6):eadk3384
6	J:339443 Zocchi L, Mehta A, Wu SC, Wu J, Gu Y, Wang J, Suh S, Spitale RC, Benavente CA, Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. Oncogenesis. 2020 Feb 18;9(2):25