Gene Expression Literature Summary

• Symbol: Tead4
• Name: TEA domain family member 4
• ID: MGI:106907

36 matching records from 36 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E2.5	E3	E3.5	E4	E6.5	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11.5	E12.5	E13.5	E14	E14.5	E15.5	E16.5	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)							1										1
In situ RNA (section)									3	1	3		2	1	2		2	2	1	2		2	2				1	1	2	5
Immunohistochemistry (whole mount)	1	1		2	1	1	4									1
In situ RNA (whole mount)							1		1	1	1		1		1		2						1
Northern blot												1				1					1					1				2
Western blot																						1					1			1
RT-PCR	4	4	1	2	3	4	6	2							3		1	1	2	1		1	1	1	1		1			9
cDNA clones																	1													2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tead4  TEA domain family member 4   (Synonyms: Etfr2, ETFR-2a, Rtef1, Tcf13r1, TEAD-4, Tef3, TEF-3, Tefr, Tefr1a)
Results	Reference
1*	J:178848 An CI, Dong Y, Hagiwara N, Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC Dev Biol. 2011;11:59
2	J:175338 Bhattaram P, Penzo-Mendez A, Sock E, Colmenares C, Kaneko KJ, Vassilev A, Depamphilis ML, Wegner M, Lefebvre V, Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun. 2010;1:9
3*	J:283946 Chatterjee S, Nandakumar P, Auer DR, Gabriel SB, Chakravarti A, Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease. Proc Natl Acad Sci U S A. 2019 Dec 9;
1	J:199467 Do DV, Ueda J, Messerschmidt DM, Lorthongpanich C, Zhou Y, Feng B, Guo G, Lin PJ, Hossain MZ, Zhang W, Moh A, Wu Q, Robson P, Ng HH, Poellinger L, Knowles BB, Solter D, Fu XY, A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo. Genes Dev. 2013 Jun 15;27(12):1378-90
4	J:338268 Dos Santos M, Shah AM, Zhang Y, Bezprozvannaya S, Chen K, Xu L, Lin W, McAnally JR, Bassel-Duby R, Liu N, Olson EN, Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution. Nat Commun. 2023 Jul 19;14(1):4333
1*	J:284140 Frum T, Watts JL, Ralston A, TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage. Development. 2019 Sep 6;146(17):dev179861
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
12*	J:35437 Jacquemin P, Hwang JJ, Martial JA, Dolle P, Davidson I, A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain. J Biol Chem. 1996 Sep 6;271(36):21775-85
7*	J:48579 Jacquemin P, Sapin V, Alsat E, Evain-Brion D, Dolle P, Davidson I, Differential expression of the TEF family of transcription factors in the murine placenta and during differentiation of primary human trophoblasts in vitro. Dev Dyn. 1998 Jul;212(3):423-36
5*	J:41029 Kaneko KJ, Cullinan EB, Latham KE, DePamphilis ML, Transcription factor mTEAD-2 is selectively expressed at the beginning of zygotic gene expression in the mouse. Development. 1997 May;124(10):1963-73
1	J:127233 Kaneko KJ, Kohn MJ, Liu C, DePamphilis ML, Transcription factor TEAD2 is involved in neural tube closure. Genesis. 2007 Sep;45(9):577-87
1	J:324027 Kappen C, Kruger C, Jones S, Salbaum JM, Nutrient Transporter Gene Expression in the Early Conceptus-Implications From Two Mouse Models of Diabetic Pregnancy. Front Cell Dev Biol. 2022;10:777844
1	J:335513 Liu W, Chen J, Yang C, Lee KF, Lee YL, Chiu PC, Zhang Y, Duan YG, Liu K, Yeung WS, Expression of microRNA let-7 in cleavage embryos modulates cell fate determination and formation of mouse blastocysts. Biol Reprod. 2022 Dec 10;107(6):1452-1463
6	J:267771 Mamidi A, Prawiro C, Seymour PA, de Lichtenberg KH, Jackson A, Serup P, Semb H, Mechanosignalling via integrins directs fate decisions of pancreatic progenitors. Nature. 2018 Dec;564(7734):114-118
1	J:275992 Menchero S, Rollan I, Lopez-Izquierdo A, Andreu MJ, Sainz de Aja J, Kang M, Adan J, Benedito R, Rayon T, Hadjantonakis AK, Manzanares M, Transitions in cell potency during early mouse development are driven by Notch. Elife. 2019 Apr 8;8:e42930
1*	J:144198 Mielcarek M, Piotrowska I, Schneider A, Gunther S, Braun T, VITO-2, a new SID domain protein, is expressed in the myogenic lineage during early mouse embryonic development. Gene Expr Patterns. 2009 Mar;9(3):129-37
1*	J:87726 Milewski RC, Chi NC, Li J, Brown C, Lu MM, Epstein JA, Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3. Development. 2004 Feb;131(4):829-37
1*	J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182
6*	J:147050 Nishioka N, Inoue K, Adachi K, Kiyonari H, Ota M, Ralston A, Yabuta N, Hirahara S, Stephenson RO, Ogonuki N, Makita R, Kurihara H, Morin-Kensicki EM, Nojima H, Rossant J, Nakao K, Niwa H, Sasaki H, The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell. 2009 Mar;16(3):398-410
9*	J:130047 Nishioka N, Yamamoto S, Kiyonari H, Sato H, Sawada A, Ota M, Nakao K, Sasaki H, Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos. Mech Dev. 2008 Mar-Apr;125(3-4):270-83
1	J:224146 O'Shaughnessy-Kirwan A, Signolet J, Costello I, Gharbi S, Hendrich B, Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification. Development. 2015 Aug 1;142(15):2586-97
2	J:283645 Peng G, Suo S, Cui G, Yu F, Wang R, Chen J, Chen S, Liu Z, Chen G, Qian Y, Tam PPL, Han JJ, Jing N, Molecular architecture of lineage allocation and tissue organization in early mouse embryo. Nature. 2019 Aug;572(7770):528-532
2	J:173642 Ribas R, Moncaut N, Siligan C, Taylor K, Cross JW, Rigby PW, Carvajal JJ, Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments. Dev Biol. 2011 Jul 15;355(2):372-80
5	J:102951 Sawada A, Nishizaki Y, Sato H, Yada Y, Nakayama R, Yamamoto S, Nishioka N, Kondoh H, Sasaki H, Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor. Development. 2005 Nov;132(21):4719-29
3*	J:285122 Sha QQ, Zhu YZ, Li S, Jiang Y, Chen L, Sun XH, Shen L, Ou XH, Fan HY, Characterization of zygotic genome activation-dependent maternal mRNA clearance in mouse. Nucleic Acids Res. 2020 Jan 24;48(2):879-894
1	J:143917 Tsika RW, Schramm C, Simmer G, Fitzsimons DP, Moss RL, Ji J, Overexpression of TEAD-1 in Transgenic Mouse Striated Muscles Produces a Slower Skeletal Muscle Contractile Phenotype. J Biol Chem. 2008 Dec 26;283(52):36154-67
1*	J:311886 Varghese PC, Rajam SM, Nandy D, Jory A, Mukherjee A, Dutta D, Histone chaperone APLF level dictates the implantation of mouse embryos. J Cell Sci. 2021 Jan 13;134(1):jcs246900
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:201607 Wu G, Han D, Gong Y, Sebastiano V, Gentile L, Singhal N, Adachi K, Fischedick G, Ortmeier C, Sinn M, Radstaak M, Tomilin A, Scholer HR, Establishment of totipotency does not depend on Oct4A. Nat Cell Biol. 2013 Sep;15(9):1089-97
6	J:351038 Wu X, Shi Y, Hu B, Zhao P, Li S, Xiao L, Wang S, Zhang K, TEAD4 regulates KRT8 and YAP in preimplantation embryos in mice but not in cattle. Reproduction. 2024 Mar 1;167(3):e230322
8*	J:126338 Yagi R, Kohn MJ, Karavanova I, Kaneko KJ, Vullhorst D, Depamphilis ML, Buonanno A, Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. Development. 2007 Nov;134(21):3827-36
6*	J:36855 Yasunami M, Suzuki K, Ohkubo H, A novel family of TEA domain-containing transcription factors with distinct spatiotemporal expression patterns. Biochem Biophys Res Commun. 1996 Nov 12;228(2):365-70
5*	J:31424 Yockey CE, Smith G, Izumo S, Shimizu N, cDNA cloning and characterization of murine transcriptional enhancer factor-1-related protein 1, a transcription factor that binds to the M-CAT motif. J Biol Chem. 1996 Feb 16;271(7):3727-36
2*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1	J:256712 Yu C, Ji SY, Dang YJ, Sha QQ, Yuan YF, Zhou JJ, Yan LY, Qiao J, Tang F, Fan HY, Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse. Cell Res. 2016 Mar;26(3):275-87