Gene Expression Literature Summary

• Symbol: Prol1
• Name: proline rich, lacrimal 1
• ID: MGI:107496

11 matching records from 11 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E14.5	E15.5	E16.5	E17.5	E18.5	E19.5	P
Immunohistochemistry (section)	1		2	3	3		9
In situ RNA (section)	1				1		2
Northern blot				1			1
Western blot				1	1		3
RT-PCR							4
cDNA clones					1
RNase protection	1	1	1	1	1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Prol1  proline rich, lacrimal 1   (Synonyms: Muc10)
Results	Reference
2	J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485
1	J:105283 Davis MA, Reynolds AB, Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland. Dev Cell. 2006 Jan;10(1):21-31
3*	J:306806 Hauser BR, Aure MH, Kelly MC, Hoffman MP, Chibly AM, Generation of a Single-Cell RNAseq Atlas of Murine Salivary Gland Development. iScience. 2020 Dec 18;23(12):101838
16*	J:49213 Jaskoll T, Chen H, Denny PC, Denny PA, Melnick M, Mouse submandibular gland mucin: embryo-specific mRNA and protein species. Mech Dev. 1998 Jun;74(1-2):179-83
1	J:105968 Jaskoll T, Zhou YM, Trump G, Melnick M, Ectodysplasin receptor-mediated signaling is essential for embryonic submandibular salivary gland development. Anat Rec A Discov Mol Cell Evol Biol. 2003 Apr;271(2):322-31
3*	J:74148 Melnick M, Chen H, Zhou Y, Jaskoll T, An alternatively spliced Muc10 glycoprotein ligand for putative L-selectin binding during mouse embryonic submandibular gland morphogenesis. Arch Oral Biol. 2001 Aug;46(8):745-57
3	J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32
5*	J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47
1	J:353621 Patel VN, Aure MH, Choi SH, Ball JR, Lane ED, Wang Z, Xu Y, Zheng C, Liu X, Martin D, Pailin JY, Prochazkova M, Kulkarni AB, van Kuppevelt TH, Ambudkar IS, Liu J, Hoffman MP, Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024 Aug 31;15(1):7584
2	J:320380 Patel VN, Pineda DL, Berenstein E, Hauser BR, Choi S, Prochazkova M, Zheng C, Goldsmith CM, van Kuppevelt TH, Kulkarni A, Song Y, Linhardt RJ, Chibly AM, Hoffman MP, Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function. Matrix Biol. 2021 Sep;103-104:37-57
3*	J:285242 Peluso G, Tian E, Abusleme L, Munemasa T, Mukaibo T, Ten Hagen KG, Loss of the disease-associated glycosyltransferase Galnt3 alters Muc10 glycosylation and the composition of the oral microbiome. J Biol Chem. 2020 Jan 31;295(5):1411-1425