Gene Expression Literature Summary

• Symbol: Ereg
• Name: epiregulin
• ID: MGI:107508

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E4	E4.5	E5.5	E6.5	E7	E7.5	E11	E11.5	E13.5	E14.5	E15	E15.5	E16.5	E17	E17.5	E18.5	E19.5	E	P
In situ RNA (section)	1	1	1	1	1		1		1	3			3				2			3
Northern blot			1	1	1	1	1	1				1			1					2
RT-PCR									1	1	2		2	2		1	2	1	1	6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ereg  epiregulin   (Synonyms: EPR)
Results	Reference
3	J:347413 Cubillos P, Ditzer N, Kolodziejczyk A, Schwenk G, Hoffmann J, Schutze TM, Derihaci RP, Birdir C, Kollner JE, Petzold A, Sarov M, Martin U, Long KR, Wimberger P, Albert M, The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex. EMBO J. 2024 Apr;43(8):1388-1419
12	J:43586 Das SK, Das N, Wang J, Lim H, Schryver B, Plowman GD, Dey SK, Expression of betacellulin and epiregulin genes in the mouse uterus temporally by the blastocyst solely at the site of its apposition is coincident with the window of implantation. Dev Biol. 1997 Oct 15;190(2):178-90
1*	J:211269 Hosur V, Johnson KR, Burzenski LM, Stearns TM, Maser RS, Shultz LD, Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin. Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2200-9
3	J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
2	J:232444 Li S, Moore AK, Zhu J, Li X, Zhou H, Lin J, He Y, Xing F, Pan Y, Bohler HC, Ding J, Cooney AJ, Lan Z, Lei Z, Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation. Biol Reprod. 2016 Feb;94(2):41
1	J:257406 Metwalli KA, Do MA, Nguyen K, Mallick S, Kin K, Farokhnia N, Jun G, Fakhouri WD, Interferon Regulatory Factor 6 Is Necessary for Salivary Glands and Pancreas Development. J Dent Res. 2018 Feb;97(2):226-236
5*	J:130339 Minami S, Iwamoto R, Mekada E, HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development. Dev Dyn. 2008 Jan;237(1):247-58
1	J:154029 Munger SC, Aylor DL, Syed HA, Magwene PM, Threadgill DW, Capel B, Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal. Genes Dev. 2009 Nov 1;23(21):2521-36
1	J:196481 Sevilla LM, Latorre V, Sanchis A, Perez P, Epidermal inactivation of the glucocorticoid receptor triggers skin barrier defects and cutaneous inflammation. J Invest Dermatol. 2013 Feb;133(2):361-70
1*	J:180844 Strauss TJ, Castrillon DH, Hammes SR, GATA-like protein-1 (GLP-1) is required for normal germ cell development during embryonic oogenesis. Reproduction. 2011 Feb;141(2):173-81
2	J:256856 Szymaniak AD, Mi R, McCarthy SE, Gower AC, Reynolds TL, Mingueneau M, Kukuruzinska M, Varelas X, The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland. Elife. 2017 May 11;6:e23499
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
5*	J:30316 Toyoda H, Komurasaki T, Ikeda Y, Yoshimoto M, Morimoto S, Molecular cloning of mouse epiregulin, a novel epidermal growth factor-related protein, expressed in the early stage of development. FEBS Lett. 1995 Dec 27;377(3):403-7
1	J:312465 Yin Y, Haller ME, Chadchan SB, Kommagani R, Ma L, Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization. JCI Insight. 2021 Sep 8;6(17)
3	J:334091 Zhang X, Xiao G, Johnson C, Cai Y, Horowitz ZK, Mennicke C, Coffey R, Haider M, Threadgill D, Eliscu R, Oldham MC, Greenbaum A, Ghashghaei HT, Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain. iScience. 2023 Mar 17;26(3):106242
1	J:201137 Zhou K, Muroyama A, Underwood J, Leylek R, Ray S, Soderling SH, Lechler T, Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3820-E3829