Gene Expression Literature Summary

• Symbol: Il11
• Name: interleukin 11
• ID: MGI:107613

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E4.5	E5.5	E6.5	E7.5	E8.5	E9.5	E10.5	E11.5	E12.5	E14	E14.5	E16.5	E18.5	E	P
Immunohistochemistry (section)	1				1		1								1
In situ RNA (section)	1	1	1	1		1									2
Northern blot										1					1
RT-PCR	1	1						1	1		1	1	3		4
RNase protection	1	1	1	1	1	1	1						1	1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Il11  interleukin 11   (Synonyms: IL-11)
Results	Reference
2	J:48920 Bilinski P, Roopenian D, Gossler A, Maternal IL-11Ralpha function is required for normal decidua and fetoplacental development in mice. Genes Dev. 1998 Jul 15;12(14):2234-43
4	J:39945 Davidson AJ, Freeman SA, Crosier KE, Wood CR, Crosier PS, Expression of murine interleukin 11 and its receptor alpha-chain in adult and embryonic tissues. Stem Cells. 1997;15(2):119-24
3	J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
3	J:171849 Mori M, Kitazume M, Ose R, Kurokawa J, Koga K, Osuga Y, Arai S, Miyazaki T, Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice. J Clin Invest. 2011 Jan 4;121(1):318-27
2*	J:36446 Morris JC, Neben S, Bennett F, Finnerty H, Long A, Beier DR, Kovacic S, McCoy JM, DiBlasio-Smith E, La Vallie ER, Caruso A, Calvetti J, Morris G, Weich N, Paul SR, Crosier PS, Turner KJ, Wood CR, Molecular cloning and characterization of murine interleukin-11. Exp Hematol. 1996 Oct;24(12):1369-76
2	J:309497 Piao X, Miura R, Miyake S, Komazawa-Sakon S, Koike M, Shindo R, Takeda J, Hasegawa A, Abe R, Nishiyama C, Mikami T, Yagita H, Uchiyama Y, Nakano H, Blockade of TNF receptor superfamily 1 (TNFR1)-dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation. J Allergy Clin Immunol. 2019 Jan;143(1):213-228.e10
12	J:46263 Robb L, Li R, Hartley L, Nandurkar HH, Koentgen F, Begley CG, Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation. Nat Med. 1998 Mar;4(3):303-8
2*	J:166908 Sasaki T, Mizuochi C, Horio Y, Nakao K, Akashi K, Sugiyama D, Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse. Development. 2010 Dec;137(23):3941-52
1	J:326954 Seong J, Frias-Aldeguer J, Holzmann V, Kagawa H, Sestini G, Heidari Khoei H, Scholte Op Reimer Y, Kip M, Pradhan SJ, Verwegen L, Vivie J, Li L, Alemany A, Korving J, Darmis F, van Oudenaarden A, Ten Berge D, Geijsen N, Rivron NC, Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero. Cell Stem Cell. 2022 Jul 7;29(7):1102-1118.e8
1	J:286073 Shindo R, Ohmuraya M, Komazawa-Sakon S, Miyake S, Deguchi Y, Yamazaki S, Nishina T, Yoshimoto T, Kakuta S, Koike M, Uchiyama Y, Konishi H, Kiyama H, Mikami T, Moriwaki K, Araki K, Nakano H, Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis. iScience. 2019 May 31;15:536-551
2*	J:174962 Sugiyama D, Kulkeaw K, Mizuochi C, Horio Y, Okayama S, Hepatoblasts comprise a niche for fetal liver erythropoiesis through cytokine production. Biochem Biophys Res Commun. 2011 Jul 1;410(2):301-6
3	J:73394 Zourbas S, Dubanchet S, Martal J, Chaouat G, Localization of pro-inflammatory (IL-12, IL-15) and anti-inflammatory (IL-11, IL-13) cytokines at the foetomaternal interface during murine pregnancy. Clin Exp Immunol. 2001 Dec;126(3):519-28