Gene Expression Literature Summary

• Symbol: Ifnb1
• Name: interferon beta 1, fibroblast
• ID: MGI:107657

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E3	E11.5	E12.5	E14.5	E17	E18.5	E19.5	E	P
Immunohistochemistry (section)											1
In situ RNA (section)						1
Northern blot						1
RT-PCR	1	1	1	1	2	4	2	3	1	1	4
RNase protection											1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ifnb1  interferon beta 1, fibroblast   (Synonyms: Ifb, IFNB, IFN-beta, interferon beta 1, fibroblast)
Results	Reference
1*	J:192255 Ahn J, Gutman D, Saijo S, Barber GN, STING manifests self DNA-dependent inflammatory disease. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19386-91
1	J:67398 Chan JC, Ganopolsky JG, Cornelissen I, Suckow MA, Sandoval-Cooper MJ, Brown EC, Noria F, Gailani D, Rosen ED, Ploplis VA, Castellino FJ, The characterization of mice with a targeted combined deficiency of protein c and factor XI. Am J Pathol. 2001 Feb;158(2):469-79
1	J:330287 de Reuver R, Verdonck S, Dierick E, Nemegeer J, Hessmann E, Ahmad S, Jans M, Blancke G, Van Nieuwerburgh F, Botzki A, Vereecke L, van Loo G, Declercq W, Hur S, Vandenabeele P, Maelfait J, ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation. Nature. 2022 Jul;607(7920):784-789
1	J:339248 Geng X, Zhang C, Li M, Wang J, Ji F, Feng H, Xing M, Li F, Zhang L, Li W, Chen Z, Hickson ID, Shen H, Ying S, PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response. Adv Sci (Weinh). 2022 Mar;9(7):e2103837
2	J:349097 Imai T, Lin J, Kaya GG, Ju E, Kondylis V, Kelepouras K, Liccardi G, Kim C, Pasparakis M, The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation. Immunity. 2024 May 7;
3	J:317376 Lin CW, Liu HY, Chen CY, Hsueh YP, Neuronally-expressed Sarm1 regulates expression of inflammatory and antiviral cytokines in brains. Innate Immun. 2014 Feb;20(2):161-72
1*	J:265968 Mannion NM, Greenwood SM, Young R, Cox S, Brindle J, Read D, Nellaker C, Vesely C, Ponting CP, McLaughlin PJ, Jantsch MF, Dorin J, Adams IR, Scadden AD, Ohman M, Keegan LP, O'Connell MA, The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell Rep. 2014 Nov 20;9(4):1482-94
1	J:242990 Newton K, Wickliffe KE, Maltzman A, Dugger DL, Strasser A, Pham VC, Lill JR, Roose-Girma M, Warming S, Solon M, Ngu H, Webster JD, Dixit VM, RIPK1 inhibits ZBP1-driven necroptosis during development. Nature. 2016 Dec 01;540(7631):129-133
3	J:141401 Okabe Y, Kawane K, Nagata S, IFN regulatory factor (IRF) 3/7-dependent and -independent gene induction by mammalian DNA that escapes degradation. Eur J Immunol. 2008 Nov;38(11):3150-8
2	J:300370 Onizawa H, Kato H, Kimura H, Kudo T, Soda N, Shimizu S, Funabiki M, Yagi Y, Nakamoto Y, Priller J, Nishikomori R, Heike T, Yan N, Tsujimura T, Mimori T, Fujita T, Aicardi-Goutieres syndrome-like encephalitis in mutant mice with constitutively active MDA5. Int Immunol. 2020 Nov 9;
1	J:175864 Porcu S, Manchinu MF, Marongiu MF, Sogos V, Poddie D, Asunis I, Porcu L, Marini MG, Moi P, Cao A, Grosveld F, Ristaldi MS, Klf1 Affects DNase II-Alpha Expression in the Central Macrophage of a Fetal Liver Erythroblastic Island: a Non-Cell-Autonomous Role in Definitive Erythropoiesis. Mol Cell Biol. 2011 Oct;31(19):4144-54
3*	J:26126 Riego E, Perez A, Martinez R, Castro FO, Lleonart R, de la Fuente J, Differential constitutive expression of interferon genes in early mouse embryos. Mol Reprod Dev. 1995 Jun;41(2):157-66
1	J:279494 Tang Y, Tu H, Zhang J, Zhao X, Wang Y, Qin J, Lin X, K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation. Nat Commun. 2019 Sep 13;10(1):4157
1	J:212272 Wu J, Bao J, Kim M, Yuan S, Tang C, Zheng H, Mastick GS, Xu C, Yan W, Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2851-7
3*	J:94874 Yoshida H, Okabe Y, Kawane K, Fukuyama H, Nagata S, Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA. Nat Immunol. 2005 Jan;6(1):49-56