Symbol Name ID |
Kif3a
kinesin family member 3A MGI:107689 |
Age | E1 | E2.5 | E3.5 | E7.5 | E8 | E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14 | E14.5 | E15.5 | E16.5 | E17.5 | E18 | E18.5 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 3 | ||||||||||||||
In situ RNA (section) | 1 | 1 | 1 | 2 | ||||||||||||||
Immunohistochemistry (whole mount) | 1 | 1 | ||||||||||||||||
Northern blot | 1 | 1 | 2 | |||||||||||||||
Western blot | 2 | 1 | 3 | |||||||||||||||
RT-PCR | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 1 | ||||||||||
cDNA clones | 2 |
Kif3a kinesin family member 3A (Synonyms: Kif3, Kifl, kinesin-II subunit, Kns3, N-4 kinesin) | |
Results | Reference |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
1 | J:213171 Cheng L, Desai J, Miranda CJ, Duncan JS, Qiu W, Nugent AA, Kolpak AL, Wu CC, Drokhlyansky E, Delisle MM, Chan WM, Wei Y, Propst F, Reck-Peterson SL, Fritzsch B, Engle EC, Human CFEOM1 mutations attenuate KIF21A autoinhibition and cause oculomotor axon stalling. Neuron. 2014 Apr 16;82(2):334-49 |
3 | J:203312 Chi L, Galtseva A, Chen L, Mo R, Hui CC, Rosenblum ND, Kif3a controls murine nephron number via GLI3 repressor, cell survival, and gene expression in a lineage-specific manner. PLoS One. 2013;8(6):e65448 |
1* | J:217609 Goggolidou P, Stevens JL, Agueci F, Keynton J, Wheway G, Grimes DT, Patel SH, Hilton H, Morthorst SK, DiPaolo A, Williams DJ, Sanderson J, Khoronenkova SV, Powles-Glover N, Ermakov A, Esapa CT, Romero R, Dianov GL, Briscoe J, Johnson CA, Pedersen LB, Norris DP, ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Development. 2014 Oct;141(20):3966-77 |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
1 | J:266273 Honda A, Kita T, Seshadri SV, Misaki K, Ahmed Z, Ladbury JE, Richardson GP, Yonemura S, Ladher RK, FGFR1-mediated protocadherin-15 loading mediates cargo specificity during intraflagellar transport in inner ear hair-cell kinocilia. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8388-8393 |
1* | J:119488 Hossain Z, Ali SM, Ko HL, Xu J, Ng CP, Guo K, Qi Z, Ponniah S, Hong W, Hunziker W, Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1631-6 |
5* | J:207074 Huang CJ, Huang CC, Chang CC, Association of the testis-specific TRIM/RBCC protein RNF33/TRIM60 with the cytoplasmic motor proteins KIF3A and KIF3B. Mol Cell Biochem. 2012 Jan;360(1-2):121-31 |
2* | J:162627 Kinzel D, Boldt K, Davis EE, Burtscher I, Trumbach D, Diplas B, Attie-Bitach T, Wurst W, Katsanis N, Ueffing M, Lickert H, Pitchfork regulates primary cilia disassembly and left-right asymmetry. Dev Cell. 2010 Jul 20;19(1):66-77 |
3* | J:54575 Marszalek JR, Ruiz-Lozano P, Roberts E, Chien KR, Goldstein LS, Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5043-8 |
5* | J:69356 Navone F, Consalez GG, Sardella M, Caspani E, Pozzoli O, Frassoni C, Morlacchi E, Sitia R, Sprocati T, Cabibbo A, Expression of KIF3C kinesin during neural development and in vitro neuronal differentiation. J Neurochem. 2001 May;77(3):741-53 |
1 | J:178434 Omori Y, Chaya T, Katoh K, Kajimura N, Sato S, Muraoka K, Ueno S, Koyasu T, Kondo M, Furukawa T, Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22671-6 |
1 | J:81741 Pennesi ME, Cho JH, Yang Z, Wu SH, Zhang J, Wu SM, Tsai MJ, BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. J Neurosci. 2003 Jan 15;23(2):453-61 |
1 | J:39117 Saito N, Okada Y, Noda Y, Kinoshita Y, Kondo S, Hirokawa N, KIFC2 is a novel neuron-specific C-terminal type kinesin superfamily motor for dendritic transport of multivesicular body-like organelles. Neuron. 1997 Mar;18(3):425-38 |
3* | J:55332 Takeda S, Yonekawa Y, Tanaka Y, Okada Y, Nonaka S, Hirokawa N, Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis. J Cell Biol. 1999 May 17;145(4):825-36 |
4* | J:35066 Yamazaki H, Nakata T, Okada Y, Hirokawa N, KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport. J Cell Biol. 1995 Sep;130(6):1387-99 |
1 | J:347414 Yang J, Zhu L, Pan H, Ueharu H, Toda M, Yang Q, Hallett SA, Olson LE, Mishina Y, A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis. J Clin Invest. 2024 Mar 11;134(8) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 10/29/2024 MGI 6.24 |
|
|