Gene Expression Literature Summary

• Symbol: Casp4
• Name: caspase 4, apoptosis-related cysteine peptidase
• ID: MGI:107700

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E3.5	E8	E11	E12	E13	E13.5	E14.5	E15	E15.5	E17	E17.5	E18.5	P
In situ RNA (section)										1		2
In situ reporter (knock in)																1
Western blot															1	1
RT-PCR	1	1	1	1	1	1	2		1		1	2		1	1	2
RNase protection						1		1			1		1			2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Casp4  caspase 4, apoptosis-related cysteine peptidase   (Synonyms: Casp11, Caspase-11, ich-3)
Results	Reference
3*	J:54598 Araki T, Saruta T, Okano H, Miura M, Caspase activity is required for nephrogenesis in the developing mouse metanephros. Exp Cell Res. 1999 May 1;248(2):423-9
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4*	J:56116 Exley GE, Tang C, McElhinny AS, Warner CM, Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos. Biol Reprod. 1999 Jul;61(1):231-9
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3	J:155983 Ikeda T, Kanazawa T, Otsuka S, Ichii O, Hashimoto Y, Kon Y, Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo. J Vet Med Sci. 2009 Sep;71(9):1161-8
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:74158 Kuechle MK, Predd HM, Fleckman P, Dale BA, Presland RB, Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse. Cell Death Differ. 2001 Aug;8(8):868-70
1*	J:252121 McCoy AM, Herington JL, Stouch AN, Mukherjee AB, Lakhdari O, Blackwell TS, Prince LS, IKKbeta Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis. Am J Pathol. 2017 Dec;187(12):2635-2644
2	J:285940 Newton K, Wickliffe KE, Maltzman A, Dugger DL, Reja R, Zhang Y, Roose-Girma M, Modrusan Z, Sagolla MS, Webster JD, Dixit VM, Activity of caspase-8 determines plasticity between cell death pathways. Nature. 2019 Nov;575(7784):679-682
5*	J:59317 Roth KA, Kuan C, Haydar TF, D'Sa-Eipper C, Shindler KS, Zheng TS, Kuida K, Flavell RA, Rakic P, Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):466-71
3*	J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188
2*	J:261957 Svandova EB, Vesela B, Lesot H, Poliard A, Matalova E, Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination. Histochem Cell Biol. 2017 Apr;147(4):497-510
1	J:171050 Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH, Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286