Symbol Name ID |
Prkar2a
protein kinase, cAMP dependent regulatory, type II alpha MGI:108025 |
Age | E8 | E8.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E18 | E18.5 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | ||||||||||||
In situ RNA (section) | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 4 | |||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | 1 | ||||||||||
Northern blot | 1 | 1 | 1 | ||||||||||||
Western blot | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | |||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 3 |
Prkar2a protein kinase, cAMP dependent regulatory, type II alpha (Synonyms: 1110061A24Rik, RII(alpha)) | |
Results | Reference |
1* | J:78010 Amieux PS, Howe DG, Knickerbocker H, Lee DC, Su T, Laszlo GS, Idzerda RL, McKnight GS, Increased basal cAMP-dependent protein kinase activity inhibits the formation of mesoderm-derived structures in the developing mouse embryo. J Biol Chem. 2002 Jul 26;277(30):27294-304 |
3* | J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247 |
2* | J:280416 Cadd G, McKnight GS, Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain. Neuron. 1989 Jul;3(1):71-9 |
8* | J:211302 de Sousa SF, Kawasaki K, Kawasaki M, Volponi AA, Gomez RS, Gomes CC, Sharpe PT, Ohazama A, PKA regulatory subunit expression in tooth development. Gene Expr Patterns. 2014 May;15(1):46-51 |
6* | J:228948 Deak VA, Skroblin P, Dittmayer C, Knobeloch KP, Bachmann S, Klussmann E, The A-kinase Anchoring Protein GSKIP Regulates GSK3beta Activity and Controls Palatal Shelf Fusion in Mice. J Biol Chem. 2016 Jan 8;291(2):681-90 |
3* | J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998; |
3* | J:25553 Greene RM, Lloyd MR, Uberti M, Nugent P, Pisano MM, Patterns of cyclic AMP-dependent protein kinase gene expression during ontogeny of the murine palate. J Cell Physiol. 1995 Jun;163(3):431-40 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
3 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
2* | J:35122 Imaizumi-Scherrer T, Faust DM, Benichou JC, Hellio R, Weiss MC, Accumulation in fetal muscle and localization to the neuromuscular junction of cAMP-dependent protein kinase A regulatory and catalytic subunits RI alpha and C alpha. J Cell Biol. 1996 Sep;134(5):1241-54 |
1* | J:268425 Li Z, Parlakian A, Coletti D, Alonso-Martin S, Hourde C, Joanne P, Gao-Li J, Blanc J, Ferry A, Paulin D, Xue Z, Agbulut O, Synemin acts as a regulator of signalling molecules during skeletal muscle hypertrophy. J Cell Sci. 2014 Nov 1;127(Pt 21):4589-601 |
3 | J:91318 Mucignat-Caretta C, Caretta A, Regional variations in the localization of insoluble kinase A regulatory isoforms during rodent brain development. J Chem Neuroanat. 2004 Jun;27(3):201-12 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
2* | J:123644 Roma G, Cobellis G, Claudiani P, Maione F, Cruz P, Tripoli G, Sardiello M, Peluso I, Stupka E, A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells. Genome Res. 2007 Jul;17(7):1051-60 |
1 | J:142482 Yin Z, Jones GN, Towns WH 2nd, Zhang X, Abel ED, Binkley PF, Jarjoura D, Kirschner LS, Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis. Circulation. 2008 Mar 18;117(11):1414-22 |
1 | J:228307 Zhou T, Li J, Zhao P, Liu H, Jia D, Jia H, He L, Cang Y, Boast S, Chen YH, Thibault H, Scherrer-Crosbie M, Goff SP, Li B, Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy. Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15666-71 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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