Symbol Name ID |
Vegfd
vascular endothelial growth factor D MGI:108037 |
Age | E7.5 | E8.5 | E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 1 | 1 | 2 | |||||||||||||
In situ RNA (section) | 1 | 1 | 1 | 1 | 2 | 2 | 3 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | ||
In situ RNA (whole mount) | 2 | 1 | 1 | 1 | |||||||||||||||
Northern blot | 1 | 1 | 1 | 1 | 1 | 2 | |||||||||||||
RT-PCR | 1 | 3 | 2 | 3 | 4 | 1 | 3 | 1 | 1 | 1 | 4 | 1 | 1 | 6 |
Vegfd vascular endothelial growth factor D (Synonyms: Figf, VEGF-D) | |
Results | Reference |
1 | J:103002 Ando Z, Sato S, Ikeda K, Kawakami K, Slc12a2 is a direct target of two closely related homeobox proteins, Six1 and Six4. FEBS J. 2005 Jun;272(12):3026-41 |
6* | J:48171 Avantaggiato V, Orlandini M, Acampora D, Oliviero S, Simeone A, Embryonic expression pattern of the murine figf gene, a growth factor belonging to platelet-derived growth factor/vascular endothelial growth factor family. Mech Dev. 1998 May;73(2):221-4 |
1* | J:69764 Baldwin ME, Catimel B, Nice EC, Roufail S, Hall NE, Stenvers KL, Karkkainen MJ, Alitalo K, Stacker SA, Achen MG, The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man. J Biol Chem. 2001 Jun 1;276(22):19166-71 |
1* | J:97571 Baldwin ME, Halford MM, Roufail S, Williams RA, Hibbs ML, Grail D, Kubo H, Stacker SA, Achen MG, Vascular endothelial growth factor D is dispensable for development of the lymphatic system. Mol Cell Biol. 2005 Mar;25(6):2441-9 |
2 | J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58 |
3 | J:159112 Bohmer R, Neuhaus B, Buhren S, Zhang D, Stehling M, Bock B, Kiefer F, Regulation of developmental lymphangiogenesis by Syk(+) leukocytes. Dev Cell. 2010 Mar 16;18(3):437-49 |
1* | J:106181 Chiellini C, Costa M, Novelli SE, Amri EZ, Benzi L, Bertacca A, Cohen P, Del Prato S, Friedman JM, Maffei M, Identification of cathepsin K as a novel marker of adiposity in white adipose tissue. J Cell Physiol. 2003 May;195(2):309-21 |
1 | J:208714 Duong T, Koltowska K, Pichol-Thievend C, Le Guen L, Fontaine F, Smith KA, Truong V, Skoczylas R, Stacker SA, Achen MG, Koopman P, Hogan BM, Francois M, VEGFD regulates blood vascular development by modulating SOX18 activity. Blood. 2014 Feb 13;123(7):1102-12 |
3* | J:54677 Farnebo F, Piehl F, Lagercrantz J, Restricted expression pattern of vegf-d in the adult and fetal mouse: high expression in the embryonic lung. Biochem Biophys Res Commun. 1999 Apr 21;257(3):891-4 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:175454 Goss AM, Tian Y, Cheng L, Yang J, Zhou D, Cohen ED, Morrisey EE, Wnt2 signaling is necessary and sufficient to activate the airway smooth muscle program in the lung by regulating myocardin/Mrtf-B and Fgf10 expression. Dev Biol. 2011 Aug 15;356(2):541-52 |
16 | J:76918 Greenberg JM, Thompson FY, Brooks SK, Shannon JM, McCormick-Shannon K, Cameron JE, Mallory BP, Akeson AL, Mesenchymal expression of vascular endothelial growth factors D and A defines vascular patterning in developing lung. Dev Dyn. 2002 Jun;224(2):144-53 |
1* | J:161785 Gu WX, Kania A, Identification of genes controlled by LMX1B in E13.5 mouse limbs. Dev Dyn. 2010 Aug;239(8):2246-55 |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
4 | J:200722 Hick AC, Delmarcelle AS, Bouquet M, Klotz S, Copetti T, Forez C, Van Der Smissen P, Sonveaux P, Collet JF, Feron O, Courtoy PJ, Pierreux CE, Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation. Dev Biol. 2013 Sep 1;381(1):227-40 |
2 | J:95386 Hiratsuka S, Kataoka Y, Nakao K, Nakamura K, Morikawa S, Tanaka S, Katsuki M, Maru Y, Shibuya M, Vascular endothelial growth factor A (VEGF-A) is involved in guidance of VEGF receptor-positive cells to the anterior portion of early embryos. Mol Cell Biol. 2005 Jan;25(1):355-63 |
3 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1* | J:153715 Jin N, Cho SN, Raso MG, Wistuba I, Smith Y, Yang Y, Kurie JM, Yen R, Evans CM, Ludwig T, Jeong JW, DeMayo FJ, Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis. Development. 2009 Oct;136(19):3347-56 |
1* | J:99326 Kuhnert F, Campagnolo L, Xiong JW, Lemons D, Fitch MJ, Zou Z, Kiosses WB, Gardner H, Stuhlmann H, Dosage-dependent requirement for mouse Vezf1 in vascular system development. Dev Biol. 2005 Jul 1;283(1):140-156 |
4 | J:109722 Lavine KJ, White AC, Park C, Smith CS, Choi K, Long F, Hui CC, Ornitz DM, Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development. Genes Dev. 2006 Jun 15;20(12):1651-66 |
1 | J:107096 Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL, VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci. 2006 Mar;9(3):340-8 |
2 | J:216439 Lee KM, Danuser R, Stein JV, Graham D, Nibbs RJ, Graham GJ, The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density. EMBO J. 2014 Nov 3;33(21):2564-80 |
1 | J:259048 Liu X, Wang Y, Liu F, Zhang M, Song H, Zhou B, Lo CW, Tong S, Hu Z, Zhang Z, Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling. Sci Signal. 2018 Feb 27;11(519) |
1 | J:286013 Outhwaite JE, Patel J, Simmons DG, Secondary Placental Defects in Cxadr Mutant Mice. Front Physiol. 2019;10:622 |
1 | J:209494 Rolfe RA, Nowlan NC, Kenny EM, Cormican P, Morris DW, Prendergast PJ, Kelly D, Murphy P, Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways. BMC Genomics. 2014;15:48 |
1 | J:182258 Taher L, Collette NM, Murugesh D, Maxwell E, Ovcharenko I, Loots GG, Global gene expression analysis of murine limb development. PLoS One. 2011;6(12):e28358 |
2* | J:82082 Tamura K, Amano T, Satoh T, Saito D, Yonei-Tamura S, Yajima H, Expression of rigf, a member of avian VEGF family, correlates with vascular patterning in the developing chick limb bud. Mech Dev. 2003 Feb;120(2):199-209 |
5* | J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23 |
3 | J:283457 Uijtdewilligen PJE, Versteeg EM, van de Westerlo EMA, van der Vlag J, Daamen WF, van Kuppevelt TH, Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development. Biomed Res Int. 2018;2018:9873471 |
2 | J:311813 VanDusen NJ, Casanovas J, Vincentz JW, Firulli BA, Osterwalder M, Lopez-Rios J, Zeller R, Zhou B, Grego-Bessa J, De La Pompa JL, Shou W, Firulli AB, Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium. Cell Rep. 2014 Dec 24;9(6):2071-83 |
1* | J:203805 Wu SP, Dong XR, Regan JN, Su C, Majesky MW, Tbx18 regulates development of the epicardium and coronary vessels. Dev Biol. 2013 Nov 15;383(2):307-20 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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