Gene Expression Literature Summary

• Symbol: Ccna1
• Name: cyclin A1
• ID: MGI:108042

51 matching records from 51 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E3.5	E8.5	E10	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E19.5	E	P
Immunohistochemistry (section)					1						3	3	1		1	1	1	1	1	1	1	2	3
In situ RNA (section)									1		1												1
In situ RNA (whole mount)	1	1	1	1
Northern blot																							1
Western blot	1	1						3		3	4	4		1	2	1	1	1	3	1			9
RT-PCR	1		1	1		1	1	1			3	1	1		1			1	2				12

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ccna1  cyclin A1
Results	Reference
3*	J:314268 Akagawa R, Nabeshima YI, Kawauchi T, Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons. Front Cell Dev Biol. 2021;9:753175
1*	J:204898 Akiyama K, Noguchi J, Hirose M, Kajita S, Katayama K, Khalaj M, Tsuji T, Fairfield H, Byers C, Reinholdt L, Ogura A, Kunieda T, A mutation in the nuclear pore complex gene Tmem48 causes gametogenesis defects in skeletal fusions with sterility (sks) mice. J Biol Chem. 2013 Nov 1;288(44):31830-41
1	J:121202 Berg T, Didon L, Nord M, Ectopic expression of C/EBPalpha in the lung epithelium disrupts late lung development. Am J Physiol Lung Cell Mol Physiol. 2006 Oct;291(4):L683-93
1*	J:157348 Burnicka-Turek O, Shirneshan K, Paprotta I, Grzmil P, Meinhardt A, Engel W, Adham IM, Inactivation of insulin-like factor 6 disrupts the progression of spermatogenesis at late meiotic prophase. Endocrinology. 2009 Sep;150(9):4348-57
2	J:266104 Choi JH, Jo HS, Lim S, Kim HT, Lee KW, Moon KH, Ha T, Kwak SS, Kim Y, Lee EJ, Joe CO, Kim JW, mTORC1 accelerates retinal development via the immunoproteasome. Nat Commun. 2018 Jun 27;9(1):2502
2	J:336417 Chong D, Gu Y, Zhang T, Xu Y, Bu D, Chen Z, Xu N, Li L, Zhu X, Wang H, Li Y, Zheng F, Wang D, Li P, Xu L, Hu Z, Li C, Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming. Cell Discov. 2022 Oct 11;8(1):106
1	J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68
1	J:57767 Dealy MJ, Nguyen KV, Lo J, Gstaiger M, Krek W, Elson D, Arbeit J, Kipreos ET, Johnson RS, Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E. Nat Genet. 1999 Oct;23(2):245-8
1	J:176023 del Barco Barrantes I, Coya JM, Maina F, Arthur JS, Nebreda AR, Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12764-9
1	J:297431 Dewhurst MR, Ow JR, Zafer G, van Hul NKM, Wollmann H, Bisteau X, Brough D, Choi H, Kaldis P, Loss of hepatocyte cell division leads to liver inflammation and fibrosis. PLoS Genet. 2020 Nov;16(11):e1009084
2	J:77297 Di Cunto F, Imarisio S, Hirsch E, Broccoli V, Bulfone A, Migheli A, Atzori C, Turco E, Triolo R, Dotto GP, Silengo L, Altruda F, Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis. Neuron. 2000 Oct;28(1):115-27
1	J:39631 Domashenko AD, Latham KE, Hatton KS, Expression of myc-family, myc-interacting, and myc-target genes during preimplantation mouse development. Mol Reprod Dev. 1997 May;47(1):57-65
1	J:305174 Dong X, Kwan KM, Yin Yang 1 is critical for mid-hindbrain neuroepithelium development and involved in cerebellar agenesis. Mol Brain. 2020 Jul 23;13(1):104
1	J:31366 Fromm L, Overbeek PA, Regulation of cyclin and cyclin-dependent kinase gene expression during lens differentiation requires the retinoblastoma protein. Oncogene. 1996 Jan 4;12(1):69-75
1	J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81
1	J:197704 Greaves EA, Copeland NA, Coverley D, Ainscough JF, Cancer-associated variant expression and interaction of CIZ1 with cyclin A1 in differentiating male germ cells. J Cell Sci. 2012 May 15;125(Pt 10):2466-77
1	J:292511 Gustafson EA, Seymour KA, Sigrist K, Rooij DGDE, Freiman RN, ZFP628 Is a TAF4b-Interacting Transcription Factor Required for Mouse Spermiogenesis. Mol Cell Biol. 2020 Mar 16;40(7)
2*	J:85296 Han J, Ito Y, Yeo JY, Sucov HM, Maas R, Chai Y, Cranial neural crest-derived mesenchymal proliferation is regulated by Msx1-mediated p19(INK4d) expression during odontogenesis. Dev Biol. 2003 Sep 1;261(1):183-96
6	J:190540 Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T, Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012 Oct;54(8):731-8
1*	J:181189 Ishimura A, Minehata K, Terashima M, Kondoh G, Hara T, Suzuki T, Jmjd5, an H3K36me2 histone demethylase, modulates embryonic cell proliferation through the regulation of Cdkn1a expression. Development. 2012 Feb;139(4):749-59
1*	J:138815 Kawaguchi A, Ikawa T, Kasukawa T, Ueda HR, Kurimoto K, Saitou M, Matsuzaki F, Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Development. 2008 Sep;135(18):3113-24
1	J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26
1*	J:92563 Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A, Sicinska E, Geng Y, Yu Q, Bhattacharya S, Bronson RT, Akashi K, Sicinski P, Mouse development and cell proliferation in the absence of D-cyclins. Cell. 2004 Aug 20;118(4):477-91
1	J:87735 Kuramochi-Miyagawa S, Kimura T, Ijiri TW, Isobe T, Asada N, Fujita Y, Ikawa M, Iwai N, Okabe M, Deng W, Lin H, Matsuda Y, Nakano T, Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development. 2004 Feb;131(4):839-49
1	J:254235 Lanctot AA, Guo Y, Le Y, Edens BM, Nowakowski RS, Feng Y, Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation. Cell Rep. 2017 Aug 1;20(5):1148-1160
1*	J:110317 Lee H, Lee DJ, Oh SP, Park HD, Nam HH, Kim JM, Lim DS, Mouse emi1 has an essential function in mitotic progression during early embryogenesis. Mol Cell Biol. 2006 Jul;26(14):5373-81
2*	J:155993 McCoy EL, Kawakami K, Ford HL, Coletta RD, Expression of Six1 homeobox gene during development of the mouse submandibular salivary gland. Oral Dis. 2009 Sep;15(6):407-13
1	J:174493 Muzio L, Soria JM, Pannese M, Piccolo S, Mallamaci A, A mutually stimulating loop involving emx2 and canonical wnt signalling specifically promotes expansion of occipital cortex and hippocampus. Cereb Cortex. 2005 Dec;15(12):2021-8
1	J:311151 Nakano T, Aochi H, Hirasaki M, Takenaka Y, Fujita K, Tamura M, Soma H, Kamezawa H, Koizumi T, Shibuya H, Inomata R, Okuda A, Murakoshi T, Shimada A, Inoue I, Effects of Ppargamma1 deletion on late-stage murine embryogenesis and cells that undergo endocycle. Dev Biol. 2021 Oct;478:222-235
1	J:202012 Pandey RR, Tokuzawa Y, Yang Z, Hayashi E, Ichisaka T, Kajita S, Asano Y, Kunieda T, Sachidanandam R, Chuma S, Yamanaka S, Pillai RS, Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16492-7
1	J:117590 Panic L, Tamarut S, Sticker-Jantscheff M, Barkic M, Solter D, Uzelac M, Grabusic K, Volarevic S, Ribosomal protein S6 gene haploinsufficiency is associated with activation of a p53-dependent checkpoint during gastrulation. Mol Cell Biol. 2006 Dec;26(23):8880-91
3	J:201041 Park DS, Tompkins RO, Liu F, Zhang J, Phoon CK, Zavadil J, Fishman GI, Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system. Biol Open. 2013;2(9):968-78
1	J:226897 Parker A, Cross SH, Jackson IJ, Hardisty-Hughes R, Morse S, Nicholson G, Coghill E, Bowl MR, Brown SD, The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells. Dis Model Mech. 2015 Dec 1;8(12):1555-68
7	J:101325 Persson JL, Zhang Q, Wang XY, Ravnik SE, Muhlrad S, Wolgemuth DJ, Distinct roles for the mammalian A-type cyclins during oogenesis. Reproduction. 2005 Oct;130(4):411-22
1	J:218949 Perucho L, Artero-Castro A, Guerrero S, Ramon y Cajal S, LLeonart ME, Wang ZQ, RPLP1, a crucial ribosomal protein for embryonic development of the nervous system. PLoS One. 2014;9(6):e99956
3	J:105554 Porse BT, Pedersen TA, Hasemann MS, Schuster MB, Kirstetter P, Luedde T, Damgaard I, Kurz E, Schjerling CK, Nerlov C, The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo. Mol Cell Biol. 2006 Feb;26(3):1028-37
3	J:129766 Sano M, Izumi Y, Helenius K, Asakura M, Rossi DJ, Xie M, Taffet G, Hu L, Pautler RG, Wilson CR, Boudina S, Abel ED, Taegtmeyer H, Scaglia F, Graham BH, Kralli A, Shimizu N, Tanaka H, Makela TP, Schneider MD, Menage-a-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1. Cell Metab. 2007 Feb;5(2):129-42
2*	J:96501 Sasaki T, Ito Y, Xu X, Han J, Bringas P Jr, Maeda T, Slavkin HC, Grosschedl R, Chai Y, LEF1 is a critical epithelial survival factor during tooth morphogenesis. Dev Biol. 2005 Feb 1;278(1):130-43
6	J:99492 Schmetsdorf S, Gartner U, Arendt T, Expression of cell cycle-related proteins in developing and adult mouse hippocampus. Int J Dev Neurosci. 2005 Feb;23(1):101-12
1*	J:242348 Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC, Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704
1	J:121692 Spruck C, Strohmaier H, Watson M, Smith AP, Ryan A, Krek TW, Reed SI, A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1. Mol Cell. 2001 Mar;7(3):639-50
1	J:315979 Tane S, Kubota M, Okayama H, Ikenishi A, Yoshitome S, Iwamoto N, Satoh Y, Kusakabe A, Ogawa S, Kanai A, Molkentin JD, Nakamura K, Ohbayashi T, Takeuchi T, Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes. J Biol Chem. 2014 Jun 27;289(26):18033-44
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
3*	J:53930 Timchenko NA, Wilde M, Darlington GJ, C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice. Mol Cell Biol. 1999 Apr;19(4):2936-45
4	J:91314 Waclaw RR, Chatot CL, Patterns of expression of cyclins A, B1, D, E and cdk 2 in preimplantation mouse embryos. Zygote. 2004 Feb;12(1):19-30
1	J:221298 Wang Y, Hu G, Liu F, Wang X, Wu M, Schwarz JJ, Zhou J, Deletion of yes-associated protein (YAP) specifically in cardiac and vascular smooth muscle cells reveals a crucial role for YAP in mouse cardiovascular development. Circ Res. 2014 Mar 14;114(6):957-65
1	J:285929 Wen T, Liu J, He X, Dong K, Hu G, Yu L, Yin Q, Osman I, Peng J, Zheng Z, Xin H, Fulton D, Du Q, Zhang W, Zhou J, Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation. Cell Death Differ. 2019 Dec;26(12):2790-2806
1	J:320691 Yadav VK, Berger JM, Singh P, Nagarajan P, Karsenty G, Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse. J Clin Invest. 2022 Feb 15;132(4):e153752
2	J:138710 Yamamoto N, Majima K, Marunouchi T, A study of the proliferating activity in lens epithelium and the identification of tissue-type stem cells. Med Mol Morphol. 2008 Jun;41(2):83-91
1	J:154374 Yoshimura T, Toyoda S, Kuramochi-Miyagawa S, Miyazaki T, Miyazaki S, Tashiro F, Yamato E, Nakano T, Miyazaki J, Gtsf1/Cue110, a gene encoding a protein with two copies of a CHHC Zn-finger motif, is involved in spermatogenesis and retrotransposon suppression in murine testes. Dev Biol. 2009 Nov 1;335(1):216-27
3*	J:39157 Zeichner-David M, Vo H, Tan H, Diekwisch T, Berman B, Thiemann F , Alcocer MD , Hsu P , Wang T , Eyna J , Caton J , Slavkin HC , MacDougall M, Timing of the expression of enamel gene products during mouse tooth development. Int J Dev Biol. 1997 Feb;41(1):27-38