Gene Expression Literature Summary

• Symbol: Bin1
• Name: bridging integrator 1
• ID: MGI:108092

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9.5	E10	E10.5	E11.5	E12.5	E14.5	E15.5	E16	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)				1								2		2
In situ RNA (section)			1	1	1		2	1	1		1	1		2
In situ RNA (whole mount)	1	1		1		1							1
Northern blot		1		1	1	1								1
Western blot												1		3
RT-PCR				2		1	1	1		1		1		3
cDNA clones		1		1					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Bin1  bridging integrator 1   (Synonyms: Amphiphysin 2, Amphl)
Results	Reference
3*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1	J:304329 Chen D, He F, Lu T, Huang J, Li M, Cai D, Huang C, Chen D, Xiong F, VPS4B deficiency causes early embryonic lethality and induces signal transduction disorders of cell endocytosis. Genesis. 2021 Mar 7;:e23415
1	J:185743 Cotney J, Leng J, Oh S, DeMare LE, Reilly SK, Gerstein MB, Noonan JP, Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb. Genome Res. 2012 Jun;22(6):1069-80
3	J:272180 Cowling BS, Prokic I, Tasfaout H, Rabai A, Humbert F, Rinaldi B, Nicot AS, Kretz C, Friant S, Roux A, Laporte J, Amphiphysin (BIN1) negatively regulates dynamin 2 for normal muscle maturation. J Clin Invest. 2017 Dec 1;127(12):4477-4487
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
6*	J:155715 Fernando P, Sandoz JS, Ding W, de Repentigny Y, Brunette S, Kelly JF, Kothary R, Megeney LA, Bin1 SRC homology 3 domain acts as a scaffold for myofiber sarcomere assembly. J Biol Chem. 2009 Oct 2;284(40):27674-86
1	J:44180 Kadlec L, Pendergast AM, The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation. Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12390-5
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:53316 Mao NC, Steingrimsson E, DuHadaway J, Wasserman W, Ruiz JC, Copeland NG , Jenkins NA , Prendergast GC, The murine Bin1 gene functions early in myogenesis and defines a new region of synteny between mouse chromosome 18 and human chromosome 2. Genomics. 1999 Feb 15;56(1):51-8
2	J:83753 Muller AJ, Baker JF, DuHadaway JB, Ge K, Farmer G, Donover PS, Meade R, Reid C, Grzanna R, Roach AH, Shah N, Soler AP, Prendergast GC, Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation. Mol Cell Biol. 2003 Jun;23(12):4295-306
2	J:65651 Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG, Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mech Dev. 2000 Nov;98(1-2):77-94
5	J:298043 Prokic I, Cowling BS, Kutchukian C, Kretz C, Tasfaout H, Gache V, Hergueux J, Wendling O, Ferry A, Toussaint A, Gavriilidis C, Nattarayan V, Koch C, Laine J, Combe R, Tiret L, Jacquemond V, Pilot-Storck F, Laporte J, Differential physiological role of BIN1 isoforms in skeletal muscle development, function and regeneration. Dis Model Mech. 2020 Sep 29;:dmm044354
5*	J:219479 Reynolds JO, Chiang DY, Wang W, Beavers DL, Dixit SS, Skapura DG, Landstrom AP, Song LS, Ackerman MJ, Wehrens XH, Junctophilin-2 is necessary for T-tubule maturation during mouse heart development. Cardiovasc Res. 2013 Oct 1;100(1):44-53
6*	J:35155 Sakamuro D, Elliott KJ, Wechsler-Reya R, Prendergast GC, BIN1 is a novel MYC-interacting protein with features of a tumour suppressor [see comments]. Nat Genet. 1996 Sep;14(1):69-77
3*	J:340074 Wu J, Moriwaki K, Asuka T, Nakai R, Kanda S, Taniguchi M, Sugiyama T, Yoshimura SI, Kunii M, Nagasawa T, Hosen N, Miyoshi E, Harada A, EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts. Blood Adv. 2023 Jul 25;7(14):3382-3394