Gene Expression Literature Summary

• Symbol: Sparcl1
• Name: SPARC-like 1
• ID: MGI:108110

22 matching records from 22 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)						1						1						1	4		3	1		5
In situ RNA (section)			1	1			1	1	2	1	1			3	2	1	1	2		1	1			4
Immunohistochemistry (whole mount)																		1						1
In situ RNA (whole mount)	1	1	1	1	1	2		1
Northern blot																							1	3
Western blot																	1							4
RT-PCR				1				1		1		2				2		1	3		1			5
cDNA clones																	1	1						1
RNase protection	1		1		1		1		1		1		1											2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sparcl1  SPARC-like 1   (Synonyms: Ecm2, hevin, mast9, Sc1)
Results	Reference
1	J:196086 Appler JM, Lu CC, Druckenbrod NR, Yu WM, Koundakjian EJ, Goodrich LV, Gata3 is a critical regulator of cochlear wiring. J Neurosci. 2013 Feb 20;33(8):3679-91
1*	J:338242 Bellchambers HM, Phatak AR, Nenni MJ, Padua MB, Gao H, Liu Y, Ware SM, Single cell RNA analysis of the left-right organizer transcriptome reveals potential novel heterotaxy genes. Sci Rep. 2023 Jul 1;13(1):10688
1*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
4*	J:263439 Deans MR, Peterson JM, Wong GW, Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1. PLoS One. 2010 Sep 15;5(9):e12765
5	J:87426 Gongidi V, Ring C, Moody M, Brekken R, Sage EH, Rakic P, Anton ES, SPARC-like 1 Regulates the Terminal Phase of Radial Glia-Guided Migration in the Cerebral Cortex. Neuron. 2004 Jan 8;41(1):57-69
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
6*	J:190034 Hurley PJ, Marchionni L, Simons BW, Ross AE, Peskoe SB, Miller RM, Erho N, Vergara IA, Ghadessi M, Huang Z, Gurel B, Park BH, Davicioni E, Jenkins RB, Platz EA, Berman DM, Schaeffer EM, Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14977-82
3*	J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27
2*	J:226028 Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA, Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103
7*	J:321931 Liu J, Wu X, Lu Q, Molecular divergence of mammalian astrocyte progenitor cells at early gliogenesis. Development. 2022 Mar 1;149(5):dev199985
6	J:187341 Lloyd-Burton S, Roskams AJ, SPARC-like 1 (SC1) is a diversely expressed and developmentally regulated matricellular protein that does not compensate for the absence of SPARC in the CNS. J Comp Neurol. 2012 Aug 15;520(12):2575-90
1	J:320197 Magaletta ME, Lobo M, Kernfeld EM, Aliee H, Huey JD, Parsons TJ, Theis FJ, Maehr R, Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development. Nat Commun. 2022 Jan 24;13(1):457
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
14*	J:59207 McKinnon PJ, McLaughlin SK, Kapsetaki M, Margolskee RF, Extracellular matrix-associated protein Sc1 is not essential for mouse development. Mol Cell Biol. 2000 Jan;20(2):656-60
1*	J:198109 Oeschger FM, Wang WZ, Lee S, Garcia-Moreno F, Goffinet AM, Arbones ML, Rakic S, Molnar Z, Gene expression analysis of the embryonic subplate. Cereb Cortex. 2012 Jun;22(6):1343-59
9*	J:50239 Ringuette M, Rogers I, Varmuza S, Rush S, Brown IR, Expression of SC1 is associated with the migration of myotomes along the dermomyotome during somitogenesis in early mouse embryos. Dev Genes Evol. 1998 Sep;208(7):403-6
1	J:302395 Shah K, King GD, Jiang H, A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells. J Mol Cell Biol. 2020 Jan 22;12(1):4-16
2	J:190524 Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, Xu J, Sadovsky Y, Barak Y, Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
9*	J:40645 Soderling JA, Reed MJ, Corsa A, Sage EH, Cloning and expression of murine SC1, a gene product homologous to SPARC. J Histochem Cytochem. 1997 Jun;45(6):823-35
1	J:326953 Wu X, Sosunov AA, Lado W, Teoh JJ, Ham A, Li H, Al-Dalahmah O, Gill BJA, Arancio O, Schevon CA, Frankel WN, McKhann GM 2nd, Sulzer D, Goldman JE, Tang G, Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex. Cell Rep. 2022 Jul 19;40(3):111085
5	J:164319 Xu Y, Zhang H, Yang H, Zhao X, Lovas S, Lundberg YW, Expression, functional, and structural analysis of proteins critical for otoconia development. Dev Dyn. 2010 Oct;239(10):2659-73
4*	J:237620 Xu Y, Zhang Y, Lundberg YW, Spatiotemporal differences in otoconial gene expression. Genesis. 2016 Dec;54(12):613-625