Gene Expression Literature Summary

• Symbol: Prkg1
• Name: protein kinase, cGMP-dependent, type I
• ID: MGI:108174

17 matching records from 17 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E17.5	P
Immunohistochemistry (section)	1	1	2	1	5	1	1	1	1	1	1	3
In situ RNA (section)	1			1	2				2
Immunohistochemistry (whole mount)	1
In situ reporter (knock in)												1
Northern blot												1
Western blot			1	1		1						3
RT-PCR			1	1	2		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Prkg1  protein kinase, cGMP-dependent, type I   (Synonyms: Prkg1b, Prkgr1b)
Results	Reference
2	J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58
4*	J:102943 Demyanenko GP, Halberstadt AI, Pryzwansky KB, Werner C, Hofmann F, Maness PF, Abnormal neocortical development in mice lacking cGMP-dependent protein kinase I. Brain Res Dev Brain Res. 2005 Nov 7;160(1):1-8
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:231595 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL, Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
2	J:184717 Luo C, Gangadharan V, Bali KK, Xie RG, Agarwal N, Kurejova M, Tappe-Theodor A, Tegeder I, Feil S, Lewin G, Polgar E, Todd AJ, Schlossmann J, Hofmann F, Liu DL, Hu SJ, Feil R, Kuner T, Kuner R, Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity. PLoS Biol. 2012 Mar;10(3):e1001283
2	J:91047 MacDonald BT, Adamska M, Meisler MH, Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. Development. 2004 Jun;131(11):2543-52
2*	J:37306 Pfeifer A, Aszodi A, Seidler U, Ruth P, Hofmann F, Fassler R, Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II. Science. 1996 Dec 20;274(5295):2082-6
1	J:267448 Schmidt H, Dickey DM, Dumoulin A, Octave M, Robinson JW, Kuhn R, Feil R, Potter LR, Rathjen FG, Regulation of the Natriuretic Peptide Receptor 2 (Npr2) by Phosphorylation of Juxtamembrane Serine and Threonine Residues Is Essential for Bifurcation of Sensory Axons. J Neurosci. 2018 Nov 7;38(45):9768-9780
3	J:346629 Schmidt H, Peters S, Frank K, Wen L, Feil R, Rathjen FG, Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3. Eur J Neurosci. 2016 Dec;44(12):2991-3000
2*	J:135081 Schmidt H, Stonkute A, Juttner R, Schaffer S, Buttgereit J, Feil R, Hofmann F, Rathjen FG, The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord. J Cell Biol. 2007 Oct 22;179(2):331-40
6	J:143238 Schmidt H, Werner M, Heppenstall PA, Henning M, More MI, Kuhbandner S, Lewin GR, Hofmann F, Feil R, Rathjen FG, cGMP-mediated signaling via cGKIalpha is required for the guidance and connectivity of sensory axons. J Cell Biol. 2002 Nov 11;159(3):489-98
5	J:310594 Ter-Avetisyan G, Dumoulin A, Herrel A, Schmidt H, Strump J, Afzal S, Rathjen FG, Loss of Axon Bifurcation in Mesencephalic Trigeminal Neurons Impairs the Maximal Biting Force in Npr2-Deficient Mice. Front Cell Neurosci. 2018;12:153
2	J:205571 Ter-Avetisyan G, Rathjen FG, Schmidt H, Bifurcation of Axons from Cranial Sensory Neurons Is Disabled in the Absence of Npr2-Induced cGMP Signaling. J Neurosci. 2014 Jan 15;34(3):737-47
2	J:263287 Troster P, Haseleu J, Petersen J, Drees O, Schmidtko A, Schwaller F, Lewin GR, Ter-Avetisyan G, Winter Y, Peters S, Feil S, Feil R, Rathjen FG, Schmidt H, The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord. Front Mol Neurosci. 2018;11:19
1	J:278320 Wolter S, Mohrle D, Schmidt H, Pfeiffer S, Zelle D, Eckert P, Kramer M, Feil R, Pilz PKD, Knipper M, Ruttiger L, GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing. Front Neural Circuits. 2018;12:65
2*	J:153667 Zhao Z, Ma L, Regulation of axonal development by natriuretic peptide hormones. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):18016-21