Symbol Name ID |
Cpeb1
cytoplasmic polyadenylation element binding protein 1 MGI:108442 |
Age | E0.5 | E1 | E2 | E2.5 | E3 | E3.5 | E13.5 | E14.5 | E16.5 | E17.5 | E18 | E18.5 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 1 | |||||||||
In situ RNA (section) | 1 | 1 | 2 | ||||||||||
Immunohistochemistry (whole mount) | 1 | 1 | |||||||||||
In situ RNA (whole mount) | 1 | ||||||||||||
Western blot | 1 | 4 | |||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 8 |
Cpeb1 cytoplasmic polyadenylation element binding protein 1 | |
Results | Reference |
1* | J:182840 Cai C, Tamai K, Molyneaux K, KHDC1B is a novel CPEB binding partner specifically expressed in mouse oocytes and early embryos. Mol Biol Cell. 2010 Sep 15;21(18):3137-48 |
1 | J:265411 Calderone V, Gallego J, Fernandez-Miranda G, Garcia-Pras E, Maillo C, Berzigotti A, Mejias M, Bava FA, Angulo-Urarte A, Graupera M, Navarro P, Bosch J, Fernandez M, Mendez R, Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease. Gastroenterology. 2016 Apr;150(4):982-97.e30 |
1 | J:170300 Chen J, Melton C, Suh N, Oh JS, Horner K, Xie F, Sette C, Blelloch R, Conti M, Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Genes Dev. 2011 Apr 1;25(7):755-66 |
1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
7* | J:91422 Evsikov AV, de Vries WN, Peaston AE, Radford EE, Fancher KS, Chen FH, Blake JA, Bult CJ, Latham KE, Solter D, Knowles BB, Systems biology of the 2-cell mouse embryo. Cytogenet Genome Res. 2004;105(2-4):240-50 |
1 | J:326362 Feng S, Li J, Wen H, Liu K, Gui Y, Wen Y, Wang X, Yuan S, hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells. Nat Commun. 2022 Jun 23;13(1):3588 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
4* | J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14 |
4 | J:265044 Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-Gonzalez JL, Pico S, Hernandez IH, Diaz-Hernandez JI, Belloc E, Rodolosse A, Parikshak NN, Penagarikano O, Fernandez-Chacon R, Irimia M, Navarro P, Geschwind DH, Mendez R, Lucas JJ, Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature. 2018 Aug;560(7719):441-446 |
2 | J:282460 Rong Y, Ji SY, Zhu YZ, Wu YW, Shen L, Fan HY, ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation. Nucleic Acids Res. 2019 Dec 2;47(21):11387-11402 |
2 | J:213445 Rutledge CE, Lau HT, Mangan H, Hardy LL, Sunnotel O, Guo F, MacNicol AM, Walsh CP, Lees-Murdock DJ, Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements. PLoS One. 2014;9(2):e88385 |
1 | J:119483 Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA, Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007 Mar 15;21(6):644-8 |
3 | J:83946 Tay J, Hodgman R, Sarkissian M, Richter JD, Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation. Genes Dev. 2003 Jun 15;17(12):1457-62 |
3 | J:102097 Tay J, Richter JD, Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice. Dev Cell. 2001 Aug;1(2):201-13 |
1* | J:326556 Wang Y, Yasmin L, Li L, Gao P, Xu X, Sun X, Godbout R, DDX1 vesicles control calcium-dependent mitochondrial activity in mouse embryos. Nat Commun. 2022 Jul 1;13(1):3794 |
1 | J:302699 Zhao LW, Zhu YZ, Chen H, Wu YW, Pi SB, Chen L, Shen L, Fan HY, PABPN1L mediates cytoplasmic mRNA decay as a placeholder during the maternal-to-zygotic transition. EMBO Rep. 2020 Aug 5;21(8):e49956 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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