Gene Expression Literature Summary

• Symbol: Htr2b
• Name: 5-hydroxytryptamine (serotonin) receptor 2B
• ID: MGI:109323

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8	E8.5	E9	E9.5	E10	E10.5	E11.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E17.5	E18	E18.5	P
Immunohistochemistry (section)		2		1	1	2	1						1		1
In situ RNA (section)							2	1	1	1		1	2	1		1	1	4
In situ RNA (whole mount)	1	1	1
In situ reporter (knock in)																		1
Western blot																		1
RT-PCR	1		1		1	2		1	1		1	1	1	2	1			6
cDNA clones																		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Htr2b  5-hydroxytryptamine (serotonin) receptor 2B   (Synonyms: 5-HT2B)
Results	Reference
1*	J:38874 Choi DS, Colas JF, Kellermann O, Loric S, Launay JM, Rosay P, Maroteaux L, The mouse 5-HT2B receptor: possible involvement in trophic functions of serotonin. Cell Mol Biol (Noisy-Le-Grand). 1994 May;40(3):403-11
8*	J:40606 Choi DS, Ward SJ, Messaddeq N, Launay JM, Maroteaux L, 5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells. Development. 1997 May;124(9):1745-55
2*	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
8	J:59184 Fiorica-Howells E, Maroteaux L, Gershon MD, Serotonin and the 5-HT(2B) receptor in the development of enteric neurons. J Neurosci. 2000 Jan 1;20(1):294-305
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
6*	J:74070 Lauder JM, Wilkie MB, Wu C, Singh S, Expression of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors in the mouse embryo. Int J Dev Neurosci. 2000 Nov;18(7):653-62
3*	J:3106 Loric S, Launay JM, Colas JF, Maroteaux L, New mouse 5-HT2-like receptor. Expression in brain, heart and intestine. FEBS Lett. 1992 Nov 9;312(2-3):203-7
1*	J:240101 Lv J, Wang L, Gao Y, Ding YQ, Liu F, 5-hydroxytryptamine synthesized in the aorta-gonad-mesonephros regulates hematopoietic stem and progenitor cell survival. J Exp Med. 2017 Feb;214(2):529-545
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
3	J:284574 Moon JH, Kim YG, Kim K, Osonoi S, Wang S, Saunders DC, Wang J, Yang K, Kim H, Lee J, Jeong JS, Banerjee RR, Kim SK, Wu Y, Mizukami H, Powers AC, German MS, Kim H, Serotonin Regulates Adult beta-Cell Mass by Stimulating Perinatal beta-Cell Proliferation. Diabetes. 2020 Feb;69(2):205-214
2	J:64067 Nebigil CG, Choi DS, Dierich A, Hickel P, Le Meur M, Messaddeq N, Launay JM, Maroteaux L, Serotonin 2B receptor is required for heart development. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9508-13
1	J:119481 Ramakrishna S, Kim IM, Petrovic V, Malin D, Wang IC, Kalin TV, Meliton L, Zhao YY, Ackerson T, Qin Y, Malik AB, Costa RH, Kalinichenko VV, Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box m1 transcription factor. Dev Dyn. 2007 Mar 15;236(4):1000-1013
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
3	J:240993 Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G, A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell. 2009 Sep 04;138(5):976-89