Gene Expression Literature Summary

• Symbol: Fadd
• Name: Fas associated via death domain
• ID: MGI:109324

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8.5	E10	E10.5	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E16	E16.5	E17.5	E18.5	E	P
In situ RNA (section)					1			1
In situ RNA (whole mount)			1							1
In situ reporter (knock in)					1											1
Northern blot	1	1		1		1				1						1
Western blot						1	1	1					1	2	1	2
RT-PCR									1		1					3
RNase protection												1		1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fadd  Fas associated via death domain   (Synonyms: Mort1/FADD)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
3	J:94928 De Paepe ME, Mao Q, Embree-Ku M, Rubin LP, Luks FI, Fas/FasL-mediated apoptosis in perinatal murine lungs. Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L730-42
1	J:284571 Fan C, Pu W, Wu X, Zhang X, He L, Zhou B, Zhang H, Lack of FADD in Tie-2 expressing cells causes RIPK3-mediated embryonic lethality. Cell Death Dis. 2016 Sep 1;7(9):e2351
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:149068 Imtiyaz HZ, Zhou X, Zhang H, Chen D, Hu T, Zhang J, The death domain of FADD is essential for embryogenesis, lymphocyte development, and proliferation. J Biol Chem. 2009 Apr 10;284(15):9917-26
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
2	J:285940 Newton K, Wickliffe KE, Maltzman A, Dugger DL, Reja R, Zhang Y, Roose-Girma M, Modrusan Z, Sagolla MS, Webster JD, Dixit VM, Activity of caspase-8 determines plasticity between cell death pathways. Nature. 2019 Nov;575(7784):679-682
2	J:242990 Newton K, Wickliffe KE, Maltzman A, Dugger DL, Strasser A, Pham VC, Lill JR, Roose-Girma M, Warming S, Solon M, Ngu H, Webster JD, Dixit VM, RIPK1 inhibits ZBP1-driven necroptosis during development. Nature. 2016 Dec 01;540(7631):129-133
1	J:261640 Peltzer N, Darding M, Montinaro A, Draber P, Draberova H, Kupka S, Rieser E, Fisher A, Hutchinson C, Taraborrelli L, Hartwig T, Lafont E, Haas TL, Shimizu Y, Boiers C, Sarr A, Rickard J, Alvarez-Diaz S, Ashworth MT, Beal A, Enver T, Bertin J, Kaiser W, Strasser A, Silke J, Bouillet P, Walczak H, LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018 May;557(7703):112-117
1*	J:165465 Sehic A, Risnes S, Khan QE, Khuu C, Osmundsen H, Gene expression and dental enamel structure in developing mouse incisor. Eur J Oral Sci. 2010 Apr;118(2):118-30
1*	J:85525 Ugolini G, Raoul C, Ferri A, Haenggeli C, Yamamoto Y, Salaun D, Henderson CE, Kato AC, Pettmann B, Hueber AO, Fas/tumor necrosis factor receptor death signaling is required for axotomy-induced death of motoneurons in vivo. J Neurosci. 2003 Sep 17;23(24):8526-31
1	J:263687 Wang CX, Cui GS, Liu X, Xu K, Wang M, Zhang XX, Jiang LY, Li A, Yang Y, Lai WY, Sun BF, Jiang GB, Wang HL, Tong WM, Li W, Wang XJ, Yang YG, Zhou Q, METTL3-mediated m6A modification is required for cerebellar development. PLoS Biol. 2018 Jun;16(6):e2004880
8*	J:46527 Yeh WC, Pompa JL, McCurrach ME, Shu HB, Elia AJ, Shahinian A , Ng M , Wakeham A , Khoo W , Mitchell K , El-Deiry WS , Lowe SW , Goeddel DV , Mak TW, FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science. 1998 Mar 20;279(5358):1954-8
1*	J:281166 Zhang X, Zhang H, Xu C, Li X, Li M, Wu X, Pu W, Zhou B, Wang H, Li D, Ding Q, Ying H, Wang H, Zhang H, Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis. Nat Commun. 2019 Sep 13;10(1):4158