Gene Expression Literature Summary
|
Symbol Name ID |
Jag1
jagged 1 MGI:1095416 |
| Age | E0.5 | E1.5 | E2 | E2.5 | E3.5 | E4 | E4.5 | E5.5 | E7.5 | E8 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19 | E19.5 | E20 | E | P |
| Immunohistochemistry (section) | 2 | 2 | 5 | 17 | 1 | 30 | 4 | 27 | 3 | 30 | 3 | 31 | 5 | 50 | 3 | 32 | 4 | 25 | 3 | 13 | 2 | 19 | 1 | 1 | 14 | 52 | ||||||||||
| In situ RNA (section) | 2 | 1 | 4 | 3 | 13 | 2 | 28 | 2 | 20 | 3 | 26 | 2 | 18 | 2 | 24 | 1 | 20 | 2 | 8 | 3 | 7 | 15 | 1 | 9 | 12 | |||||||||||
| Immunohistochemistry (whole mount) | 1 | 1 | 1 | 2 | 4 | 3 | 2 | 1 | 1 | |||||||||||||||||||||||||||
| In situ RNA (whole mount) | 2 | 1 | 9 | 6 | 12 | 4 | 22 | 4 | 9 | 2 | 7 | 1 | 2 | 1 | 1 | 1 | 2 | 7 | 1 | |||||||||||||||||
| In situ reporter (knock in) | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 2 | 1 | ||||||||||||||||||||||||||
| Northern blot | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | ||||||||||||||||||||||||||
| Western blot | 1 | 1 | 1 | 1 | 3 | 1 | 7 | 2 | 1 | 1 | 2 | 1 | 8 | |||||||||||||||||||||||
| RT-PCR | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 3 | 4 | 16 | 2 | 17 | 3 | 8 | 4 | 17 | 6 | 27 | 4 | 28 | 6 | 13 | 5 | 21 | 4 | 8 | 5 | 14 | 1 | 1 | 5 | 49 | ||
| cDNA clones | 1 | 1 | 1 | 1 |
| Jag1 jagged 1 (Synonyms: ABE2, Gsfabe2, Headturner, Htu, Ozz, Serrate-1) | |
| Results | Reference |
| 1* | J:176660 Abler LL, Keil KP, Mehta V, Joshi PS, Schmitz CT, Vezina CM, A high-resolution molecular atlas of the fetal mouse lower urogenital tract. Dev Dyn. 2011 Oct;240(10):2364-77 |
| 1 | J:178999 Ahnfelt-Ronne J, Jorgensen MC, Klinck R, Jensen JN, Fuchtbauer EM, Deering T, Macdonald RJ, Wright CV, Madsen OD, Serup P, Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism. Development. 2012 Jan;139(1):33-45 |
| 2 | J:165557 Ambler CA, Watt FM, Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1. Development. 2010 Nov;137(21):3569-79 |
| 1 | J:187218 Andersson LS, Larhammar M, Memic F, Wootz H, Schwochow D, Rubin CJ, Patra K, Arnason T, Wellbring L, Hjalm G, Imsland F, Petersen JL, McCue ME, Mickelson JR, Cothran G, Ahituv N, Roepstorff L, Mikko S, Vallstedt A, Lindgren G, Andersson L, Kullander K, Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice. Nature. 2012 Aug 30;488(7413):642-6 |
| 2 | J:150973 Antoniou A, Raynaud P, Cordi S, Zong Y, Tronche F, Stanger BZ, Jacquemin P, Pierreux CE, Clotman F, Lemaigre FP, Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology. 2009 Jun;136(7):2325-33 |
| 4 | J:251150 Aoki H, Ogino H, Tomita H, Hara A, Kunisada T, Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells. PLoS One. 2016;11(9):e0163042 |
| 2 | J:57072 Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H, Notch signalling controls pancreatic cell differentiation. Nature. 1999 Aug 26;400(6747):877-81 |
| 1 | J:328140 Asgarian Z, Oliveira MG, Stryjewska A, Maragkos I, Rubin AN, Magno L, Pachnis V, Ghorbani M, Hiebert SW, Denaxa M, Kessaris N, MTG8 interacts with LHX6 to specify cortical interneuron subtype identity. Nat Commun. 2022 Sep 5;13(1):5217 |
| 4 | J:264269 Azimi M, Le TT, Brown NL, Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens. Differentiation. 2018 Jul - Aug;102:40-52 |
| 1* | J:316418 Azzoni E, Frontera V, Anselmi G, Rode C, James C, Deltcheva EM, Demian AS, Brown J, Barone C, Patelli A, Harman JR, Nicholls M, Conway SJ, Morrissey E, Jacobsen SEW, Sparrow DB, Harris AL, Enver T, de Bruijn MFTR, The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition. Cell Rep. 2021 Dec 14;37(11):110103 |
| 1 | J:226938 Bagherie-Lachidan M, Reginensi A, Pan Q, Zaveri HP, Scott DA, Blencowe BJ, Helmbacher F, McNeill H, Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool. Development. 2015 Aug 1;142(15):2564-73 |
| 2 | J:262507 Barker N, Rookmaaker MB, Kujala P, Ng A, Leushacke M, Snippert H, van de Wetering M, Tan S, Van Es JH, Huch M, Poulsom R, Verhaar MC, Peters PJ, Clevers H, Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development. Cell Rep. 2012 Sep 27;2(3):540-52 |
| 2* | J:54606 Barrantes IB, Elia AJ, Wunsch K, De Angelis MH, Mak TW, Rossant J, Conlon RA, Gossler A, de la Pompa JL, Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse. Curr Biol. 1999 May 6;9(9):470-80 |
| 2* | J:102528 Barsi JC, Rajendra R, Wu JI, Artzt K, Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Mech Dev. 2005 Oct;122(10):1106-17 |
| 1 | J:239394 Basch ML, Brown RM, Jen HI, Semerci F, Depreux F, Edlund RK, Zhang H, Norton CR, Gridley T, Cole SE, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves AK, Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife. 2016 Dec 14;5:e19921 |
| 2 | J:173382 Basch ML, Ohyama T, Segil N, Groves AK, Canonical Notch Signaling Is Not Necessary for Prosensory Induction in the Mouse Cochlea: Insights from a Conditional Mutant of RBPj{kappa}. J Neurosci. 2011 Jun 1;31(22):8046-58 |
| 3 | J:243561 Basta JM, Robbins L, Denner DR, Kolar GR, Rauchman M, A Sall1-NuRD interaction regulates multipotent nephron progenitors and is required for loop of Henle formation. Development. 2017 Sep 01;144(17):3080-3094 |
| 5 | J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58 |
| 2 | J:283343 Bastida MF, Perez-Gomez R, Trofka A, Zhu J, Rada-Iglesias A, Sheth R, Stadler HS, Mackem S, Ros MA, The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1090-1096 |
| 1 | J:327336 Bertol JW, Johnston S, Ahmed R, Xie VK, Hubka KM, Cruz L, Nitschke L, Stetsiv M, Goering JP, Nistor P, Lowell S, Hoskens H, Claes P, Weinberg SM, Saadi I, Farach-Carson MC, Fakhouri WD, TWIST1 interacts with beta/delta-catenins during neural tube development and regulates fate transition in cranial neural crest cells. Development. 2022 Aug 1;149(15):dev200068 |
| 2 | J:249355 Bicker F, Vasic V, Horta G, Ortega F, Nolte H, Kavyanifar A, Keller S, Stankovic ND, Harter PN, Benedito R, Lutz B, Bauerle T, Hartwig J, Baumgart J, Kruger M, Radyushkin K, Alberi L, Berninger B, Schmidt MHH, Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception. Nat Commun. 2017 Jun 28;8:15922 |
| 1 | J:282886 Blackwood CA, Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone. Neuroscience. 2019 Aug 10;413:230-238 |
| 2 | J:291930 Blackwood CA, Bailetti A, Nandi S, Gridley T, Hebert JM, Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice. Front Cell Dev Biol. 2020;8:113 |
| 3 | J:159112 Bohmer R, Neuhaus B, Buhren S, Zhang D, Stehling M, Bock B, Kiefer F, Regulation of developmental lymphangiogenesis by Syk(+) leukocytes. Dev Cell. 2010 Mar 16;18(3):437-49 |
| 1 | J:232968 Boivin FJ, Sarin S, Lim J, Javidan A, Svajger B, Khalili H, Bridgewater D, Stromally expressed beta-catenin modulates Wnt9b signaling in the ureteric epithelium. PLoS One. 2015;10(3):e0120347 |
| 6 | J:219394 Boroviak T, Loos R, Bertone P, Smith A, Nichols J, The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Nat Cell Biol. 2014 Jun;16(6):516-28 |
| 2* | J:149467 Bosman EA, Quint E, Fuchs H, Hrabe de Angelis M, Steel KP, Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome. Dev Biol. 2009 Apr 15;328(2):285-96 |
| 1 | J:163537 Bouchard M, de Caprona D, Busslinger M, Xu P, Fritzsch B, Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation. BMC Dev Biol. 2010 Aug 20;10(1):89 |
| 1 | J:185338 Boucherat O, Chakir J, Jeannotte L, The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways. Biol Open. 2012;q:677-691 |
| 3 | J:239317 Bourke LM, Del Monte-Nieto G, Outhwaite JE, Bharti V, Pollock PM, Simmons DG, Adam A, Hur SS, Maghzal GJ, Whitelaw E, Stocker R, Suter CM, Harvey RP, Harten SK, Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse. Differentiation. 2017 Mar - Apr;94:8-20 |
| 2* | J:271281 Bowles J, Feng CW, Ineson J, Miles K, Spiller CM, Harley VR, Sinclair AH, Koopman P, Retinoic Acid Antagonizes Testis Development in Mice. Cell Rep. 2018 Jul 31;24(5):1330-1341 |
| 2* | J:313372 Braccioli L, Vervoort SJ, Adolfs Y, Heijnen CJ, Basak O, Pasterkamp RJ, Nijboer CH, Coffer PJ, FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression. Stem Cell Reports. 2017 Nov 14;9(5):1530-1545 |
| 1 | J:279716 Braitsch CM, Azizoglu DB, Htike Y, Barlow HR, Schnell U, Chaney CP, Carroll TJ, Stanger BZ, Cleaver O, LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382 |
| 2 | J:164021 Bremer J, O'Connor T, Tiberi C, Rehrauer H, Weis J, Aguzzi A, Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. PLoS One. 2010;5(8):e12450 |
| 3 | J:76133 Brennan J, Karl J, Capel B, Divergent Vascular Mechanisms Downstream of Sry Establish the Arterial System in the XY Gonad. Dev Biol. 2002 Apr 15;244(2):418-28 |
| 2 | J:154462 Breuskin I, Bodson M, Thelen N, Thiry M, Borgs L, Nguyen L, Lefebvre PP, Malgrange B, Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti. Dev Biol. 2009 Nov 15;335(2):327-39 |
| 7 | J:310741 Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML, Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Dev Cell. 2014 Dec 22;31(6):707-21 |
| 4 | J:107414 Brooker R, Hozumi K, Lewis J, Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear. Development. 2006 Apr;133(7):1277-86 |
| 3* | J:289914 Brown RM 2nd, Nelson JC, Zhang H, Kiernan AE, Groves AK, Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development. Dev Biol. 2020 Jun 1;462(1):74-84 |
| 1 | J:92326 Burton Q, Cole LK, Mulheisen M, Chang W, Wu DK, The role of Pax2 in mouse inner ear development. Dev Biol. 2004 Aug 1;272(1):161-75 |
| 1 | J:153595 Butterfield NC, Metzis V, McGlinn E, Bruce SJ, Wainwright BJ, Wicking C, Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb. Development. 2009 Oct;136(20):3515-24 |
| 1 | J:199162 Cai T, Seymour ML, Zhang H, Pereira FA, Groves AK, Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci. 2013 Jun 12;33(24):10110-22 |
| 1 | J:261286 Cai Y, Tang X, Chen X, Li X, Wang Y, Bao X, Wang L, Sun D, Zhao J, Xing Y, Warner M, Xu H, Gustafsson JA, Fan X, Liver X receptor beta regulates the development of the dentate gyrus and autistic-like behavior in the mouse. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2725-E2733 |
| 1 | J:186083 Calderon L, Boehm T, Synergistic, context-dependent, and hierarchical functions of epithelial components in thymic microenvironments. Cell. 2012 Mar 30;149(1):159-72 |
| 1 | J:289039 Candi E, Rufini A, Terrinoni A, Giamboi-Miraglia A, Lena AM, Mantovani R, Knight R, Melino G, DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):11999-2004 |
| 1 | J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21 |
| 3 | J:276713 Cargill K, Hemker SL, Clugston A, Murali A, Mukherjee E, Liu J, Bushnell D, Bodnar AJ, Saifudeen Z, Ho J, Bates CM, Kostka D, Goetzman ES, Sims-Lucas S, Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation. J Am Soc Nephrol. 2019 Jul;30(7):1192-1205 |
| 2 | J:108618 Carson C, Murdoch B, Roskams AJ, Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium. Dev Dyn. 2006 Jun;235(6):1678-88 |
| 2 | J:161794 Catela C, Kratsios P, Hede M, Lang F, Rosenthal N, Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis. Dev Dyn. 2010 Aug;239(8):2149-60 |
| 1* | J:75936 Cau E, Casarosa S, Guillemot F, Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage. Development. 2002 Apr;129(8):1871-80 |
| 2 | J:173579 Chai R, Xia A, Wang T, Jan TA, Hayashi T, Bermingham-McDonogh O, Cheng AG, Dynamic expression of lgr5, a wnt target gene, in the developing and mature mouse cochlea. J Assoc Res Otolaryngol. 2011 Aug;12(4):455-69 |
| 4* | J:243789 Chang AH, Raftrey BC, D'Amato G, Surya VN, Poduri A, Chen HI, Goldstone AB, Woo J, Fuller GG, Dunn AR, Red-Horse K, DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes Dev. 2017 Aug 04;31(13):1308-1324 |
| 1 | J:136636 Chang W, Lin Z, Kulessa H, Hebert J, Hogan BL, Wu DK, Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements. PLoS Genet. 2008 Apr;4(4):e1000050 |
| 1 | J:224823 Chen AC, Donovan A, Ned-Sykes R, Andrews NC, Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11714-9 |
| 1* | J:105958 Chen J, Lu L, Shi S, Stanley P, Expression of Notch signaling pathway genes in mouse embryos lacking beta4galactosyltransferase-1. Gene Expr Patterns. 2006 Apr;6(4):376-82 |
| 4 | J:97734 Chen L, Al-Awqati Q, Segmental expression of Notch and Hairy genes in nephrogenesis. Am J Physiol Renal Physiol. 2005 May;288(5):F939-52 |
| 1 | J:173587 Chen W, Jiang H, Wang M, Jin J, Feng S, Bi Y, Wang H, Mao Y, Shou Z, Chen J, Effects of chlorpyrifos exposure on kidney Notch2-Jagged1 pathway of early prenatal embryo. Birth Defects Res B Dev Reprod Toxicol. 2011 Apr;92(2):97-101 |
| 1 | J:119907 Cheng HT, Kim M, Valerius MT, Surendran K, Schuster-Gossler K, Gossler A, McMahon AP, Kopan R, Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development. 2007 Feb;134(4):801-11 |
| 1 | J:267108 Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y, Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development. J Biol Chem. 2018 Jul 27;293(30):11659-11673 |
| 3 | J:174608 Chong DC, Koo Y, Xu K, Fu S, Cleaver O, Stepwise arteriovenous fate acquisition during mammalian vasculogenesis. Dev Dyn. 2011 Sep;240(9):2153-65 |
| 6 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
| 1 | J:237525 Chung E, Deacon P, Marable S, Shin J, Park JS, Notch signaling promotes nephrogenesis by downregulating Six2. Development. 2016 Nov 01;143(21):3907-3913 |
| 2 | J:253680 Chung E, Deacon P, Park JS, Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation. Development. 2017 Dec 15;144(24):4530-4539 |
| 1 | J:198502 Clarke RL, Yzaguirre AD, Yashiro-Ohtani Y, Bondue A, Blanpain C, Pear WS, Speck NA, Keller G, The expression of Sox17 identifies and regulates haemogenic endothelium. Nat Cell Biol. 2013 May;15(5):502-10 |
| 2 | J:41258 Cohen B, Bashirullah A, Dagnino L, Campbell C, Fisher WW, Leow CC , Whiting E , Ryan D , Zinyk D , Boulianne G , Hui CC , Gallie B , Phillips RA , Lipshitz HD , Egan SE, Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila. Nat Genet. 1997 Jul;16(3):283-8 |
| 2 | J:273460 Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X, Crk proteins transduce FGF signaling to promote lens fiber cell elongation. Elife. 2018 Jan 23;7:e32586 |
| 1 | J:274119 Combes AN, Wilson S, Phipson B, Binnie BB, Ju A, Lawlor KT, Cebrian C, Walton SL, Smyth IM, Moritz KM, Kopan R, Oshlack A, Little MH, Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number. Kidney Int. 2018 Mar;93(3):589-598 |
| 1 | J:169692 Copeland JN, Feng Y, Neradugomma NK, Fields PE, Vivian JL, Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac. BMC Dev Biol. 2011;11:12 |
| 1 | J:163848 Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, Taketo MM, Iruela-Arispe ML, Adams RH, Dejana E, The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev Cell. 2010 Jun 15;18(6):938-49 |
| 2 | J:206194 Corada M, Orsenigo F, Morini MF, Pitulescu ME, Bhat G, Nyqvist D, Breviario F, Conti V, Briot A, Iruela-Arispe ML, Adams RH, Dejana E, Sox17 is indispensable for acquisition and maintenance of arterial identity. Nat Commun. 2013;4:2609 |
| 4* | J:93160 Cormier S, Vandormael-Pournin S, Babinet C, Cohen-Tannoudji M, Developmental expression of the Notch signaling pathway genes during mouse preimplantation development. Gene Expr Patterns. 2004 Oct;4(6):713-7 |
| 1 | J:171226 Cullen M, Elzarrad MK, Seaman S, Zudaire E, Stevens J, Yang MY, Li X, Chaudhary A, Xu L, Hilton MB, Logsdon D, Hsiao E, Stein EV, Cuttitta F, Haines DC, Nagashima K, Tessarollo L, St Croix B, GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5759-64 |
| 8 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
| 1 | J:331483 D'Amato G, Phansalkar R, Naftaly JA, Fan X, Amir ZA, Rios Coronado PE, Cowley DO, Quinn KE, Sharma B, Caron KM, Vigilante A, Red-Horse K, Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4. Dev Cell. 2022 Nov 21;57(22):2517-2532.e6 |
| 1 | J:142229 Dabdoub A, Puligilla C, Jones JM, Fritzsch B, Cheah KS, Pevny LH, Kelley MW, Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18396-401 |
| 2 | J:321232 Dash S, Brastrom LK, Patel SD, Scott CA, Slusarski DC, Lachke SA, The master transcription factor SOX2, mutated in anophthalmia/microphthalmia, is post-transcriptionally regulated by the conserved RNA-binding protein RBM24 in vertebrate eye development. Hum Mol Genet. 2020 Mar 13;29(4):591-604 |
| 1* | J:225905 Dash S, Dang CA, Beebe DC, Lachke SA, Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn. 2015 Oct;244(10):1313-27 |
| 2 | J:321806 Dave JM, Chakraborty R, Ntokou A, Saito J, Saddouk FZ, Feng Z, Misra A, Tellides G, Riemer RK, Urban Z, Kinnear C, Ellis J, Mital S, Mecham R, Martin KA, Greif DM, JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency. J Clin Invest. 2022 Mar 1;132(5):e142338 |
| 2 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
| 1 | J:297083 De Zoysa P, Liu J, Toubat O, Choi J, Moon A, Gill PS, Duarte A, Sucov HM, Kumar SR, Delta-like ligand 4-mediated Notch signaling controls proliferation of second heart field progenitor cells by regulating Fgf8 expression. Development. 2020 Sep 11;147(17):dev185249 |
| 1 | J:330268 De Zoysa P, Toubat O, Harvey DC, Yi C, Liu J, Cavallero S, Hong YK, Sucov HM, Kumar SR, Delta-like ligand-4 regulates Notch-mediated maturation of second heart field progenitor-derived pharyngeal arterial endothelial cells. J Cell Mol Med. 2022 Oct;26(20):5181-5194 |
| 1 | J:287010 Deacon P, Concodora CW, Chung E, Park JS, beta-catenin regulates the formation of multiple nephron segments in the mouse kidney. Sci Rep. 2019 Nov 4;9(1):15915 |
| 2 | J:202074 Defalco T, Saraswathula A, Briot A, Iruela-Arispe ML, Capel B, Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling. Biol Reprod. 2013 Apr;88(4):91 |
| 5 | J:178290 del Monte G, Casanova JC, Guadix JA, MacGrogan D, Burch JB, Perez-Pomares JM, de la Pompa JL, Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis. Circ Res. 2011 Apr 1;108(7):824-36 |
| 1* | J:124179 Del Monte G, Grego-Bessa J, Gonzalez-Rajal A, Bolos V, De La Pompa JL, Monitoring Notch1 activity in development: Evidence for a feedback regulatory loop. Dev Dyn. 2007 Sep;236(9):2594-614 |
| 2 | J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7 |
| 2 | J:221164 Di Giovanni V, Walker KA, Bushnell D, Schaefer C, Sims-Lucas S, Puri P, Bates CM, Fibroblast growth factor receptor-Frs2alpha signaling is critical for nephron progenitors. Dev Biol. 2015 Apr 1;400(1):82-93 |
| 3 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
| 1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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