Symbol Name ID |
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1 MGI:109601 |
Age | E7.5 | E8.5 | E10.5 | E11.5 | E12.5 | E16 | E16.5 | E17.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | ||||||||
In situ RNA (section) | 1 | 1 | ||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 1 | 2 | |||||
Northern blot | 1 | |||||||||
Western blot | 1 | |||||||||
RT-PCR | 1 | |||||||||
cDNA clones | 1 | 1 | 1 |
Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 (Synonyms: 6330586M15Rik, D230010O13Rik, Nck) | |
Results | Reference |
2 | J:112701 Bailey PJ, Klos JM, Andersson E, Karlen M, Kallstrom M, Ponjavic J, Muhr J, Lenhard B, Sandelin A, Ericson J, A global genomic transcriptional code associated with CNS-expressed genes. Exp Cell Res. 2006 Oct 1;312(16):3108-19 |
4* | J:83956 Bladt F, Aippersbach E, Gelkop S, Strasser GA, Nash P, Tafuri A, Gertler FB, Pawson T, The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network. Mol Cell Biol. 2003 Jul;23(13):4586-97 |
3* | J:50097 Chen M, She H, Davis EM, Spicer CM, Kim L, Ren R, Le Beau MM, Li W, Identification of Nck family genes, chromosomal localization, expression, and signaling specificity. J Biol Chem. 1998 Sep 25;273(39):25171-8 |
1 | J:224419 Clouthier DL, Harris CN, Harris RA, Martin CE, Puri MC, Jones N, Requisite role for Nck adaptors in cardiovascular development, endothelial-to-mesenchymal transition, and directed cell migration. Mol Cell Biol. 2015 May;35(9):1573-87 |
1 | J:196018 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W, Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26;2(1):52-61 |
1* | J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9 |
3 | J:224947 Lane C, Qi J, Fawcett JP, NCK is critical for the development of deleted in colorectal cancer (DCC) sensitive spinal circuits. J Neurochem. 2015 Sep;134(6):1008-14 |
1 | J:39581 Margolis B, Silvennoinen O, Comoglio F, Roonprapunt C, Skolnik E, Ullrich A, Schlessinger J, High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8894-8 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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