Gene Expression Literature Summary

• Symbol: Bmal1
• Name: basic helix-loop-helix ARNT like 1
• ID: MGI:1096381

25 matching records from 25 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E2.5	E3	E3.5	E4.5	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)																	1	1	1			1	1		1	2			4
In situ RNA (section)													1			3		2		3				1		1			5
In situ RNA (whole mount)											1									1
Northern blot																1													1
Western blot														1			1			1	1								1
RT-PCR	1	1	1	2	2	2	2	1		2	2	2	1	1	2	1	3	4	2	4	2	4	3	2	2	3	3	1	11
cDNA clones																													1
RNase protection									1							1								1					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Bmal1  basic helix-loop-helix ARNT like 1   (Synonyms: Arnt3, Arntl, bHLHe5, MOP3)
Results	Reference
7*	J:145877 Amano T, Matsushita A, Hatanaka Y, Watanabe T, Oishi K, Ishida N, Anzai M, Mitani T, Kato H, Kishigami S, Saeki K, Hosoi Y, Iritani A, Matsumoto K, Expression and functional analyses of circadian genes in mouse oocytes and preimplantation embryos: cry1 is involved in the meiotic process independently of circadian clock regulation. Biol Reprod. 2009 Mar;80(3):473-83
2	J:146792 Ansari N, Agathagelidis M, Lee C, Korf HW, von Gall C, Differential maturation of circadian rhythms in clock gene proteins in the suprachiasmatic nucleus and the pars tuberalis during mouse ontogeny. Eur J Neurosci. 2009 Feb;29(3):477-89
11*	J:325107 Cao X, Yan Y, Luo X, Yang X, Cui H, Yang Y, Li H, Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice. J Mol Histol. 2022 Apr;53(2):473-482
4	J:305435 Demarez C, De Assis LVM, Krohn M, Ramella N, Schwaninger M, Oster H, Astiz M, The trophoblast clock controls transport across placenta in mice. Development. 2021 Apr 15;148(8):dev197673
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
12*	J:158725 Dolatshad H, Cary AJ, Davis FC, Differential expression of the circadian clock in maternal and embryonic tissues of mice. PLoS One. 2010;5(3):e9855
1*	J:152838 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD, A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci. 2009 Sep 9;29(36):11399-408
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
3*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
7*	J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
7	J:47665 Hogenesch JB, Gu YZ, Jain S, Bradfield CA, The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. Proc Natl Acad Sci U S A. 1998 May 12;95(10):5474-9
3	J:327273 Jidigam VK, Sawant OB, Fuller RD, Wilcots K, Singh R, Lang RA, Rao S, Neuronal Bmal1 regulates retinal angiogenesis and neovascularization in mice. Commun Biol. 2022 Aug 6;5(1):792
2*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
3*	J:326947 Ono M, Toyoda N, Kagami K, Hosono T, Matsumoto T, Horike SI, Yamazaki R, Nakamura M, Mizumoto Y, Fujiwara T, Ando H, Fujiwara H, Daikoku T, Uterine Deletion of Bmal1 Impairs Placental Vascularization and Induces Intrauterine Fetal Death in Mice. Int J Mol Sci. 2022 Jul 11;23(14)
1	J:223990 Parsons MJ, Brancaccio M, Sethi S, Maywood ES, Satija R, Edwards JK, Jagannath A, Couch Y, Finelli MJ, Smyllie NJ, Esapa C, Butler R, Barnard AR, Chesham JE, Saito S, Joynson G, Wells S, Foster RG, Oliver PL, Simon MM, Mallon AM, Hastings MH, Nolan PM, The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis. Cell. 2015 Jul 30;162(3):607-21
10*	J:161413 Ratajczak CK, Herzog ED, Muglia LJ, Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse. Reprod Fertil Dev. 2010;22(5):743-50
1	J:161526 Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H, Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development. Nat Med. 2010 Jun;16(6):678-86
4	J:293722 Sawant OB, Jidigam VK, Fuller RD, Zucaro OF, Kpegba C, Yu M, Peachey NS, Rao S, The circadian clock gene Bmal1 is required to control the timing of retinal neurogenesis and lamination of Muller glia in the mouse retina. FASEB J. 2019 Aug;33(8):8745-8758
2*	J:49044 Takahata S, Sogawa K, Kobayashi A, Ema M, Mimura J, Ozaki N, Fujii-Kuriyama Y, Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock. Biochem Biophys Res Commun. 1998 Jul 30;248(3):789-94
1	J:316473 Tampakakis E, Gangrade H, Glavaris S, Htet M, Murphy S, Lin BL, Liu T, Saberi A, Miyamoto M, Kowalski W, Mukouyama YS, Lee G, Minichiello L, Kwon C, Heart neurons use clock genes to control myocyte proliferation. Sci Adv. 2021 Dec 3;7(49):eabh4181
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
5	J:244108 Umemura Y, Koike N, Ohashi M, Tsuchiya Y, Meng QJ, Minami Y, Hara M, Hisatomi M, Yagita K, Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development. Proc Natl Acad Sci U S A. 2017 Sep 05;114(36):E7479-E7488
1	J:96328 Warnecke M, Oster H, Revelli JP, Alvarez-Bolado G, Eichele G, Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception. Genes Dev. 2005 Mar 1;19(5):614-25
8	J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311
5*	J:170399 Zheng L, Papagerakis S, Schnell SD, Hoogerwerf WA, Papagerakis P, Expression of clock proteins in developing tooth. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):202-6