Gene Expression Literature Summary

• Symbol: P2rx3
• Name: purinergic receptor P2X, ligand-gated ion channel, 3
• ID: MGI:1097160

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E2	E3	E3.5	E9.5	E10	E10.5	E11.5	E13.5	E14.5	E16.5	E17.5	E18.5	P
Immunohistochemistry (section)				1	1	1	1	1	3	5	1	3	8
In situ RNA (section)									2				6
RT-PCR	1	1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

P2rx3  purinergic receptor P2X, ligand-gated ion channel, 3   (Synonyms: 4930513E20Rik, MGC:28163, P2X3)
Results	Reference
5*	J:79527 Boldogkoi Z, Schutz B, Sallach J, Zimmer A, P2X(3) receptor expression at early stage of mouse embryogenesis. Mech Dev. 2002 Oct;118(1-2):255
2	J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77
1	J:70560 Chen Z, Rebelo S, White F, Malmberg AB, Baba H, Lima D, Woolf CJ, Basbaum AI, Anderson DJ, The paired homeodomain protein drg11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron. 2001 Jul 19;31(1):59-73
3*	J:119954 Cui XS, Li XY, Shen XH, Bae YJ, Kang JJ, Kim NH, Transcription profile in mouse four-cell, morula, and blastocyst: Genes implicated in compaction and blastocoel formation. Mol Reprod Dev. 2007 Feb;74(2):133-43
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:260552 Donnelly CR, Shah AA, Mistretta CM, Bradley RM, Pierchala BA, Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E516-E525
1	J:160718 Dykes IM, Lanier J, Eng SR, Turner EE, Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation. Neural Dev. 2010;5:3
1	J:214972 Fei D, Huang T, Krimm RF, The neurotrophin receptor p75 regulates gustatory axon branching and promotes innervation of the tongue during development. Neural Dev. 2014;9:15
3	J:209845 Fei D, Krimm RF, Taste neurons consist of both a large TrkB-receptor-dependent and a small TrkB-receptor-independent subpopulation. PLoS One. 2013;8(12):e83460
1*	J:206879 Huang T, Krimm RF, BDNF and NT4 play interchangeable roles in gustatory development. Dev Biol. 2014 Feb 15;386(2):308-20
1*	J:217303 Koudelka J, Horn JM, Vatanashevanopakorn C, Minichiello L, Genetic dissection of TrkB activated signalling pathways required for specific aspects of the taste system. Neural Dev. 2014;9:21
1*	J:186470 Lopes C, Liu Z, Xu Y, Ma Q, Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15
1	J:221586 Lou S, Pan X, Huang T, Duan B, Yang FC, Yang J, Xiong M, Liu Y, Ma Q, Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors. J Neurosci. 2015 Apr 1;35(13):5317-29
2*	J:126484 Luo W, Wickramasinghe SR, Savitt JM, Griffin JW, Dawson TM, Ginty DD, A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
1	J:97000 Morikawa Y, Tamura S, Minehata K, Donovan PJ, Miyajima A, Senba E, Essential function of oncostatin m in nociceptive neurons of dorsal root ganglia. J Neurosci. 2004 Feb 25;24(8):1941-7
1	J:264453 Newbern JM, Li X, Shoemaker SE, Zhou J, Zhong J, Wu Y, Bonder D, Hollenback S, Coppola G, Geschwind DH, Landreth GE, Snider WD, Specific functions for ERK/MAPK signaling during PNS development. Neuron. 2011 Jan 13;69(1):91-105
1*	J:225328 Ren AJ, Wang K, Zhang H, Liu A, Ma X, Liang Q, Cao D, Wood JN, He DZ, Ding YQ, Yuan WJ, Xie Z, Zhang WJ, ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons. Nat Commun. 2014;5:4984
4	J:108169 Ruan HZ, Moules E, Burnstock G, Changes in P2X3 purinoceptors in sensory ganglia of the mouse during embryonic and postnatal development. Histochem Cell Biol. 2004 Dec;122(6):539-51
4	J:302429 Wang Z, Jung JS, Inbar TC, Rangoussis KM, Faaborg-Andersen C, Coate TM, The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug;7(4):ENEURO.0179-20.2020
1	J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45