Gene Expression Literature Summary

• Symbol: Nrg3
• Name: neuregulin 3
• ID: MGI:1097165

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E4	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15.5	E16	E17.5	E18	E18.5	P
Immunohistochemistry (section)			1		2	1	2		1	1		1
In situ RNA (section)		1	2	1	2	1	3		1	3	1			3	4
In situ RNA (whole mount)		1	1		2
Northern blot	1	1						1			1		1		2
RT-PCR		1					1		1	1			1		3
cDNA clones															1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nrg3  neuregulin 3   (Synonyms: ska)
Results	Reference
2*	J:84706 Assimacopoulos S, Grove EA, Ragsdale CW, Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex. J Neurosci. 2003 Jul 23;23(16):6399-403
4	J:250702 Bartolini G, Sanchez-Alcaniz JA, Osorio C, Valiente M, Garcia-Frigola C, Marin O, Neuregulin 3 Mediates Cortical Plate Invasion and Laminar Allocation of GABAergic Interneurons. Cell Rep. 2017 Jan 31;18(5):1157-1170
2*	J:106953 Bovetti S, De Marchis S, Gambarotta G, Fasolo A, Perroteau I, Puche AC, Bovolin P, Differential expression of neuregulins and their receptors in the olfactory bulb layers of the developing mouse. Brain Res. 2006 Mar 10;1077(1):37-47
1*	J:94401 Brown N, Deb K, Paria BC, Das SK, Reese J, Embryo-uterine interactions via the neuregulin family of growth factors during implantation in the mouse. Biol Reprod. 2004 Dec;71(6):2003-11
1	J:263064 Elliott KH, Millington G, Brugmann SA, A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development. Dev Dyn. 2018 Jun;247(6):818-831
4*	J:270199 Hayes LN, Shevelkin A, Zeledon M, Steel G, Chen PL, Obie C, Pulver A, Avramopoulos D, Valle D, Sawa A, Pletnikov MV, Neuregulin 3 Knockout Mice Exhibit Behaviors Consistent with Psychotic Disorders. Mol Neuropsychiatry. 2016 Jul;2(2):79-87
6*	J:100495 Howard B, Panchal H, McCarthy A, Ashworth A, Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification. Genes Dev. 2005 Sep 1;19(17):2078-90
3	J:184363 Li H, Chou SJ, Hamasaki T, Perez-Garcia CG, O'Leary DD, Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations. Neural Dev. 2012;7:10
3	J:219260 Rakic S, Kanatani S, Hunt D, Faux C, Cariboni A, Chiara F, Khan S, Wansbury O, Howard B, Nakajima K, Nikolic M, Parnavelas JG, Cdk5 Phosphorylation of ErbB4 is Required for Tangential Migration of Cortical Interneurons. Cereb Cortex. 2015 Apr;25(4):991-1003
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
2	J:201966 Toritsuka M, Kimoto S, Muraki K, Landek-Salgado MA, Yoshida A, Yamamoto N, Horiuchi Y, Hiyama H, Tajinda K, Keni N, Illingworth E, Iwamoto T, Kishimoto T, Sawa A, Tanigaki K, Deficits in microRNA-mediated Cxcr4/Cxcl12 signaling in neurodevelopmental deficits in a 22q11 deletion syndrome mouse model. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17552-7
1	J:105744 Tsai HH, Macklin WB, Miller RH, Netrin-1 is required for the normal development of spinal cord oligodendrocytes. J Neurosci. 2006 Feb 15;26(7):1913-22
1*	J:231699 Voutilainen M, Lindfors PH, Trela E, Lonnblad D, Shirokova V, Elo T, Rysti E, Schmidt-Ullrich R, Schneider P, Mikkola ML, Ectodysplasin/NF-kappaB Promotes Mammary Cell Fate via Wnt/beta-catenin Pathway. PLoS Genet. 2015 Nov;11(11):e1005676
6*	J:135516 Wansbury O, Panchal H, James M, Parry S, Ashworth A, Howard B, Dynamic expression of Erbb pathway members during early mammary gland morphogenesis. J Invest Dermatol. 2008 Apr;128(4):1009-21
7*	J:42826 Zhang D, Sliwkowski MX, Mark M, Frantz G, Akita R, Sun Y, Hillan K , Crowley C , Brush J , Godowski PJ, Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9562-7
3	J:334091 Zhang X, Xiao G, Johnson C, Cai Y, Horowitz ZK, Mennicke C, Coffey R, Haider M, Threadgill D, Eliscu R, Oldham MC, Greenbaum A, Ghashghaei HT, Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain. iScience. 2023 Mar 17;26(3):106242