Gene Expression Literature Summary

• Symbol: Elavl1
• Name: ELAV like RNA binding protein 1
• ID: MGI:1100851

31 matching records from 31 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3	E3.5	E7	E8.5	E9	E10	E10.5	E11	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18.5	E19	E19.5	E	P
Immunohistochemistry (section)													2	5	3	1	2		2	1	2		1	2				6
In situ RNA (section)													1	1	2		1		4	1	1							4
Immunohistochemistry (whole mount)	1	1	1	1	1	1																						1
In situ RNA (whole mount)								1			3			2	3
In situ reporter (knock in)																												1
Northern blot							1					1						1				1						2
Western blot										1			1		2	1	1	1	1		1		2		1	1		9
RT-PCR	2	1	1	1	1	2		1	1	1	1			1	2				2	1	1		2					5
cDNA clones															1													3
RNase protection																											1
Nuclease S1											1		1	1	1				1		1
Primer Extension							1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Elavl1  ELAV like RNA binding protein 1   (Synonyms: 2410055N02Rik, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R), Hua, HuR, W91709)
Results	Reference
1	J:163290 Abdelmohsen K, Hutchison ER, Lee EK, Kuwano Y, Kim MM, Masuda K, Srikantan S, Subaran SS, Marasa BS, Mattson MP, Gorospe M, miR-375 inhibits differentiation of neurites by lowering HuD levels. Mol Cell Biol. 2010 Sep;30(17):4197-210
6*	J:51307 Atasoy U, Watson J, Patel D, Keene JD, ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. J Cell Sci. 1998 Nov;111(Pt 21):3145-56
3	J:311486 Chalupnikova K, Solc P, Sulimenko V, Sedlacek R, Svoboda P, An oocyte-specific ELAVL2 isoform is a translational repressor ablated from meiotically competent antral oocytes. Cell Cycle. 2014;13(7):1187-200
1*	J:148410 Combes AN, Lesieur E, Harley VR, Sinclair AH, Little MH, Wilhelm D, Koopman P, Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Dev Dyn. 2009 May;238(5):1033-41
14*	J:91422 Evsikov AV, de Vries WN, Peaston AE, Radford EE, Fancher KS, Chen FH, Blake JA, Bult CJ, Latham KE, Solter D, Knowles BB, Systems biology of the 2-cell mouse embryo. Cytogenet Genome Res. 2004;105(2-4):240-50
2*	J:163648 Fairbridge NA, Dawe CE, Niri FH, Kooistra MK, King-Jones K, McDermid HE, Cecr2 mutations causing exencephaly trigger misregulation of mesenchymal/ectodermal transcription factors. Birth Defects Res A Clin Mol Teratol. 2010 Aug;88(8):619-25
3	J:182988 Garcia-Dominguez DJ, Morello D, Cisneros E, Kontoyiannis DL, Frade JM, Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis. Mol Biol Cell. 2011 Apr 15;22(8):1227-39
4	J:152865 Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH, Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol. 2009 Aug 15;332(2):273-86
11*	J:66029 Gouble A, Morello D, Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development. Oncogene. 2000 Nov 9;19(47):5377-84
5*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:333012 Han X, Shen X, Wang M, Wang X, Jian Y, Yang C, Guo W, Loss of RNA-Binding Protein HuR Leads to Defective Ependymal Cells and Hydrocephalus. J Neurosci. 2022 Jan 12;42(2):202-219
3	J:149149 Katsanou V, Milatos S, Yiakouvaki A, Sgantzis N, Kotsoni A, Alexiou M, Harokopos V, Aidinis V, Hemberger M, Kontoyiannis DL, The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development. Mol Cell Biol. 2009 May;29(10):2762-76
3	J:60302 King PH, Fuller JJ, Nabors LB, Detloff PJ, Analysis of the 5' end of the mouse Elavl1 (mHuA) gene reveals a transcriptional regulatory element and evidence for conserved genomic organization. Gene. 2000 Jan 25;242(1-2):125-31
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
5	J:216392 Kraushar ML, Thompson K, Wijeratne HR, Viljetic B, Sakers K, Marson JW, Kontoyiannis DL, Buyske S, Hart RP, Rasin MR, Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3815-24
1	J:169836 Lachke SA, Alkuraya FS, Kneeland SC, Ohn T, Aboukhalil A, Howell GR, Saadi I, Cavallesco R, Yue Y, Tsai AC, Nair KS, Cosma MI, Smith RS, Hodges E, Alfadhli SM, Al-Hajeri A, Shamseldin HE, Behbehani A, Hannon GJ, Bulyk ML, Drack AV, Anderson PJ, John SW, Maas RL, Mutations in the RNA granule component TDRD7 cause cataract and glaucoma. Science. 2011 Mar 25;331(6024):1571-6
3	J:286293 Li M, Zhuang Y, Batra R, Thomas JD, Li M, Nutter CA, Scotti MM, Carter HA, Wang ZJ, Huang XS, Pu CQ, Swanson MS, Xie W, HNRNPA1-induced spliceopathy in a transgenic mouse model of myotonic dystrophy. Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5472-5477
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2	J:234972 McDermott BT, Ellis S, Bou-Gharios G, Clegg PD, Tew SR, RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes. Osteoarthritis Cartilage. 2016 Jul;24(7):1263-73
4*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
13	J:62325 Okano HJ, Darnell RB, A hierarchy of Hu RNA binding proteins in developing and adult neurons. J Neurosci. 1997 May 1;17(9):3024-37
1	J:168641 Park D, Xiang AP, Mao FF, Zhang L, Di CG, Liu XM, Shao Y, Ma BF, Lee JH, Ha KS, Walton N, Lahn BT, Nestin is required for the proper self-renewal of neural stem cells. Stem Cells. 2010 Dec;28(12):2162-71
3	J:188151 Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M, Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012 Jul;8(7):e1002823
5	J:173650 Sgantzis N, Yiakouvaki A, Remboutsika E, Kontoyiannis DL, HuR controls lung branching morphogenesis and mesenchymal FGF networks. Dev Biol. 2011 Jun 15;354(2):267-79
1*	J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
1	J:343100 Takada Y, Fierro L, Sato K, Sanada T, Ishii A, Yamamoto T, Kotani T, Mature mRNA processing that deletes 3' end sequences directs translational activation and embryonic development. Sci Adv. 2023 Nov 24;9(47):eadg6532
1	J:171050 Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH, Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
5	J:299244 Wang Y, Guo Y, Tang C, Han X, Xu M, Sun J, Zhao Y, Zhang Y, Wang M, Cao X, Zhu X, Guo W, Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis. Cell Rep. 2019 Dec 3;29(10):3101-3117.e7
8	J:341968 Weber AI, Parthasarathy S, Borisova E, Epifanova E, Preussner M, Rusanova A, Ambrozkiewicz MC, Bessa P, Newman AG, Muller L, Schaal H, Heyd F, Tarabykin V, Srsf1 and Elavl1 act antagonistically on neuronal fate choice in the developing neocortex by controlling TrkC receptor isoform expression. Nucleic Acids Res. 2023 Oct 27;51(19):10218-10237
1	J:316159 Yu Q, Du M, Zhang W, Liu L, Gao Z, Chen W, Gu Y, Zhu K, Niu X, Sun Q, Wang L, Mesenteric Neural Crest Cells Are the Embryological Basis of Skip Segment Hirschsprung's Disease. Cell Mol Gastroenterol Hepatol. 2021;12(1):1-24
10	J:297167 Zhao YF, He XX, Song ZF, Guo Y, Zhang YN, Yu HL, He ZX, Xiong WC, Guo W, Zhu XJ, Human antigen R-regulated mRNA metabolism promotes the cell motility of migrating mouse neurons. Development. 2020 Mar 16;147(6):dev183509