Gene Expression Literature Summary

• Symbol: Dnah11
• Name: dynein, axonemal, heavy chain 11
• ID: MGI:1100864

17 matching records from 17 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11.5	E12.5	E14.5	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)																1
In situ RNA (section)		2	1	1		1		1	1	1						2
In situ RNA (whole mount)		3	5	1			1
In situ reporter (knock in)		1	3	1				1							1	2
Western blot																2
RT-PCR	1		1		1	1	1				1	1	2	1	1	2
cDNA clones																2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dnah11  dynein, axonemal, heavy chain 11   (Synonyms: avc4, b2b1203Clo, b2b1279Clo, b2b1289Clo, b2b1727Clo, b2b598Clo, Dnahc11, lrd)
Results	Reference
2	J:182741 Alten L, Schuster-Gossler K, Beckers A, Groos S, Ulmer B, Hegermann J, Ochs M, Gossler A, Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1. Development. 2012 Apr;139(7):1276-84
1	J:222988 Beckers A, Alten L, Viebahn C, Andre P, Gossler A, The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15765-70
3*	J:237132 Burnicka-Turek O, Steimle JD, Huang W, Felker L, Kamp A, Kweon J, Peterson M, Reeves RH, Maslen CL, Gruber PJ, Yang XH, Shendure J, Moskowitz IP, Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms. Hum Mol Genet. 2016 Jul 15;25(14):3011-3028
1*	J:50025 Chen J, Knowles HJ, Hebert JL, Hackett BP, Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry. J Clin Invest. 1998 Sep 15;102(6):1077-82
1	J:166761 Cruz C, Ribes V, Kutejova E, Cayuso J, Lawson V, Norris D, Stevens J, Davey M, Blight K, Bangs F, Mynett A, Hirst E, Chung R, Balaskas N, Brody SL, Marti E, Briscoe J, Foxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signalling. Development. 2010 Dec;137(24):4271-82
2*	J:257338 Dougherty GW, Loges NT, Klinkenbusch JA, Olbrich H, Pennekamp P, Menchen T, Raidt J, Wallmeier J, Werner C, Westermann C, Ruckert C, Mirra V, Hjeij R, Memari Y, Durbin R, Kolb-Kokocinski A, Praveen K, Kashef MA, Kashef S, Eghtedari F, Haffner K, Valmari P, Baktai G, Aviram M, Bentur L, Amirav I, Davis EE, Katsanis N, Brueckner M, Shaposhnykov A, Pigino G, Dworniczak B, Omran H, DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes. Am J Respir Cell Mol Biol. 2016 Aug;55(2):213-24
1	J:297786 Dougherty GW, Mizuno K, Nothe-Menchen T, Ikawa Y, Boldt K, Ta-Shma A, Aprea I, Minegishi K, Pang YP, Pennekamp P, Loges NT, Raidt J, Hjeij R, Wallmeier J, Mussaffi H, Perles Z, Elpeleg O, Rabert F, Shiratori H, Letteboer SJ, Horn N, Young S, Strunker T, Stumme F, Werner C, Olbrich H, Takaoka K, Ide T, Twan WK, Biebach L, Grosse-Onnebrink J, Klinkenbusch JA, Praveen K, Bracht DC, Hoben IM, Junger K, Gutzlaff J, Cindric S, Aviram M, Kaiser T, Memari Y, Dzeja PP, Dworniczak B, Ueffing M, Roepman R, Bartscherer K, Katsanis N, Davis EE, Amirav I, Hamada H, Omran H, CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module. Nat Commun. 2020 Nov 2;11(1):5520
1*	J:77529 Essner JJ, Vogan KJ, Wagner MK, Tabin CJ, Yost HJ, Brueckner M, Conserved function for embryonic nodal cilia. Nature. 2002 Jul 4;418(6893):37-8
1	J:76233 Faisst AM, Alvarez-Bolado G, Treichel D, Gruss P, Rotatin is a novel gene required for axial rotation and left-right specification in mouse embryos. Mech Dev. 2002 Apr;113(1):15-28
1*	J:119488 Hossain Z, Ali SM, Ko HL, Xu J, Ng CP, Guo K, Qi Z, Ponniah S, Hong W, Hunziker W, Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1631-6
2*	J:306217 Lee H, Ko HW, Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development. BMB Rep. 2020 Jul;53(7):367-372
8*	J:107740 McGrath J, Somlo S, Makova S, Tian X, Brueckner M, Two populations of node monocilia initiate left-right asymmetry in the mouse. Cell. 2003 Jul 11;114(1):61-73
1	J:104377 Nakaya MA, Biris K, Tsukiyama T, Jaime S, Rawls JA, Yamaguchi TP, Wnt3alinks left-right determination with segmentation and anteroposterior axis elongation. Development. 2005 Dec;132(24):5425-36
1*	J:286656 Shylo NA, Emmanouil E, Ramrattan D, Weatherbee SD, Loss of ciliary transition zone protein TMEM107 leads to heterotaxy in mice. Dev Biol. 2020 Apr 15;460(2):187-199
1*	J:252050 Sung YH, Baek IJ, Kim YH, Gho YS, Oh SP, Lee YJ, Lee HW, PIERCE1 is critical for specification of left-right asymmetry in mice. Sci Rep. 2016 Jun 16;6:27932
12	J:44522 Supp DM, Brueckner M, Kuehn MR, Witte DP, Lowe LA, McGrath J, Corrales J, Potter SS, Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries. Development. 1999 Dec;126(23):5495-504
8	J:44093 Supp DM, Witte DP, Potter SS, Brueckner M, Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice. Nature. 1997 Oct 30;389(6654):963-6