Gene Expression Literature Summary

• Symbol: Dsc3
• Name: desmocollin 3
• ID: MGI:1194993

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1	E2	E2.5	E3.5	E4	E6.5	E7.5	E8.5	E9.5	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14.5	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)					1	1								1				1	1	1	1	2	1	1	1	1	3
In situ RNA (section)						1					1	1	1	2		3	2	3		1				2		1	2
Immunohistochemistry (whole mount)	1	1	1
In situ RNA (whole mount)										2	1	1	1	1	1	3	1	1		1
In situ reporter (knock in)																		1									1
Northern blot												1		1		1	1	1		1		1		1
Western blot				1																							2
RT-PCR			1	1	1		1	1	1			1				2	1							1			2
cDNA clones																											2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dsc3  desmocollin 3   (Synonyms: 5430426I24Rik)
Results	Reference
3*	J:51129 Bierkamp C, Schwarz H, Huber O, Kemler R, Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice. Development. 1999 Jan;126(2):371-81
12	J:44061 Chidgey MA, Yue KK, Gould S, Byrne C, Garrod DR, Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development. Dev Dyn. 1997 Nov;210(3):315-27
4*	J:165759 Chiu HS, Szucsik JC, Georgas KM, Jones JL, Rumballe BA, Tang D, Grimmond SM, Lewis AG, Aronow BJ, Lessard JL, Little MH, Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation. Dev Biol. 2010 Aug 15;344(2):1071-87
1	J:272423 Choi YJ, Laclef C, Yang N, Andreu-Cervera A, Lewis J, Mao X, Li L, Snedecor ER, Takemaru KI, Qin C, Schneider-Maunoury S, Shroyer KR, Hannun YA, Koch PJ, Clark RA, Payne AS, Kowalczyk AP, Chen J, RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis. PLoS Genet. 2019 Jan;15(1):e1007914
1	J:83058 Ciani L, Patel A, Allen ND, Ffrench-Constant C, Mice Lacking the Giant Protocadherin mFAT1 Exhibit Renal Slit Junction Abnormalities and a Partially Penetrant Cyclopia and Anophthalmia Phenotype. Mol Cell Biol. 2003 May;23(10):3575-82
26	J:105239 Den Z, Cheng X, Merched-Sauvage M, Koch PJ, Desmocollin 3 is required for pre-implantation development of the mouse embryo. J Cell Sci. 2006 Feb 1;119(Pt 3):482-9
4	J:191121 Ferone G, Mollo MR, Thomason HA, Antonini D, Zhou H, Ambrosio R, De Rosa L, Salvatore D, Getsios S, van Bokhoven H, Dixon J, Missero C, p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome. Hum Mol Genet. 2013 Feb 1;22(3):531-43
1	J:320249 Godsel LM, Roth-Carter QR, Koetsier JL, Tsoi LC, Huffine AL, Broussard JA, Fitz GN, Lloyd SM, Kweon J, Burks HE, Hegazy M, Amagai S, Harms PW, Xing X, Kirma J, Johnson JL, Urciuoli G, Doglio LT, Swindell WR, Awatramani R, Sprecher E, Bao X, Cohen-Barak E, Missero C, Gudjonsson JE, Green KJ, Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor. J Clin Invest. 2022 Feb 1;132(3):e144363
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:253459 Inoue SI, Takahara S, Yoshikawa T, Niihori T, Yanai K, Matsubara Y, Aoki Y, Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice. Hum Mol Genet. 2017 Dec 1;26(23):4715-4727
6*	J:44442 King IA, Angst BD, Hunt DM, Kruger M, Arnemann J, Buxton RS, Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse. Differentiation. 1997 Nov;62(2):83-96
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:309667 Kousa YA, Fuller E, Schutte BC, IRF6 and AP2A Interaction Regulates Epidermal Development. J Invest Dermatol. 2018 Dec;138(12):2578-2588
4	J:116077 Richardson RJ, Dixon J, Malhotra S, Hardman MJ, Knowles L, Boot-Handford RP, Shore P, Whitmarsh A, Dixon MJ, Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch. Nat Genet. 2006 Nov;38(11):1329-34
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
2	J:202875 Tokonzaba E, Chen J, Cheng X, Den Z, Ganeshan R, Muller EJ, Koch PJ, Plakoglobin as a regulator of desmocollin gene expression. J Invest Dermatol. 2013 Dec;133(12):2732-40
6*	J:327901 Ye Q, Bhojwani A, Hu JK, Understanding the development of oral epithelial organs through single cell transcriptomic analysis. Development. 2022 Aug 15;149(16):dev200539
1	J:262458 Zhang L, Ferreyros M, Feng W, Hupe M, Crumrine DA, Chen J, Elias PM, Holleran WM, Niswander L, Hohl D, Williams T, Torchia EC, Roop DR, Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis. PLoS One. 2016;11(8):e0161465