Gene Expression Literature Summary

• Symbol: Cdk8
• Name: cyclin dependent kinase 8
• ID: MGI:1196224

6 matching records from 6 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2.5	E3	E3.5	E4.5	E5	E5.5	E9.5	E11.5	E14.5	E18.5	P
Immunohistochemistry (section)	1	1	1	1	1	1	1	1			1
In situ reporter (knock in)										1
Western blot													1
RT-PCR									1		1	1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cdk8  cyclin dependent kinase 8   (Synonyms: MGC:37111)
Results	Reference
1*	J:45218 Ahuja HS, Zhu Y, Zakeri Z, Association of cyclin-dependent kinase 5 and its activator p35 with apoptotic cell death. Dev Genet. 1997;21(4):258-67
4*	J:347774 Kolonay DW, Sattler KM, Strawser C, Rafael-Fortney J, Mihaylova MM, Miller KE, Lepper C, Baskin KK, Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease. Front Cell Dev Biol. 2024;12:1331563
8	J:307869 Lynch CJ, Bernad R, Martinez-Val A, Shahbazi MN, Nobrega-Pereira S, Calvo I, Blanco-Aparicio C, Tarantino C, Garreta E, Richart-Gines L, Alcazar N, Grana-Castro O, Gomez-Lopez G, Aksoy I, Munoz-Martin M, Martinez S, Ortega S, Prieto S, Simboeck E, Camasses A, Stephan-Otto Attolini C, Fernandez AF, Sierra MI, Fraga MF, Pastor J, Fisher D, Montserrat N, Savatier P, Munoz J, Zernicka-Goetz M, Serrano M, Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases. Nat Cell Biol. 2020 Oct;22(10):1223-1238
1	J:304183 Ponce JM, Coen G, Spitler KM, Dragisic N, Martins I, Hinton A Jr, Mungai M, Tadinada SM, Zhang H, Oudit GY, Song LS, Li N, Sicinski P, Strack S, Abel ED, Mitchell C, Hall DD, Grueter CE, Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics. J Am Heart Assoc. 2020 Apr 7;9(7):e014366
1*	J:125327 Westerling T, Kuuluvainen E, Makela TP, Cdk8 is essential for preimplantation mouse development. Mol Cell Biol. 2007 Sep;27(17):6177-82
1	J:187715 Xie L, Hoffmann AD, Burnicka-Turek O, Friedland-Little JM, Zhang K, Moskowitz IP, Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation. Dev Cell. 2012 Aug 14;23(2):280-91