Gene Expression Literature Summary

• Symbol: Gtf2i
• Name: general transcription factor II I
• ID: MGI:1202722

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1	E1.5	E2	E2.5	E3	E3.5	E4.5	E7	E8	E9	E10.5	E11	E12	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E17	E18	E	P
Immunohistochemistry (section)							1		1	1		1	1					1		1				2
In situ RNA (section)														1	3	1	2					1		3
In situ RNA (whole mount)						1					1								2				1
In situ reporter (knock in)																							1
Northern blot								1				1						1			1			1
Western blot															2	1								1
RT-PCR	1	1	1	1	1	1	1					1	1		2									6
cDNA clones																								1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gtf2i  general transcription factor II I   (Synonyms: 6030441I21Rik, BAP-135, TFII-I)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
3	J:90537 Danoff SK, Taylor HE, Blackshaw S, Desiderio S, TFII-I, a candidate gene for Williams syndrome cognitive profile: parallels between regional expression in mouse brain and human phenotype. Neuroscience. 2004;123(4):931-8
2*	J:87377 Enkhmandakh B, Bitchevaia N, Ruddle F, Bayarsaihan D, The early embryonic expression of TFII-I during mouse preimplantation development. Gene Expr Patterns. 2004 Jan;4(1):25-8
2	J:143508 Enkhmandakh B, Makeyev AV, Erdenechimeg L, Ruddle FH, Chimge NO, Tussie-Luna MI, Roy AL, Bayarsaihan D, Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):181-6
7*	J:163633 Fijalkowska I, Sharma D, Bult CJ, Danoff SK, Expression of the transcription factor, TFII-I, during post-implantation mouse embryonic development. BMC Res Notes. 2010;3:203
1*	J:152838 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD, A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci. 2009 Sep 9;29(36):11399-408
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
7*	J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
3	J:284943 Kopp N, McCullough K, Maloney SE, Dougherty JD, Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models. Hum Mol Genet. 2019 Oct 15;28(20):3443-3465
2*	J:295322 Kopp ND, Nygaard KR, Liu Y, McCullough KB, Maloney SE, Gabel HW, Dougherty JD, Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences. Hum Mol Genet. 2020 Jun 3;29(9):1498-1519
1*	J:302708 Liu HB, Muhammad T, Guo Y, Li MJ, Sha QQ, Zhang CX, Liu H, Zhao SG, Zhao H, Zhang H, Du YZ, Sun K, Liu K, Lu G, Guo XJ, Sha J, Fan HY, Gao F, Chen ZJ, RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation. Adv Sci (Weinh). 2019 Aug 7;6(15):1900295
1	J:204278 Lucena J, Pezzi S, Aso E, Valero MC, Carreiro C, Dubus P, Sampaio A, Segura M, Barthelemy I, Zindel MY, Sousa N, Barbero JL, Maldonado R, Perez-Jurado LA, Campuzano V, Essential role of the N-terminal region of TFII-I in viability and behavior. BMC Med Genet. 2010;11:61
3*	J:145764 Makeyev AV, Bayarsaihan D, Alternative splicing and promoter use in TFII-I genes. Gene. 2009 Mar 15;433(1-2):16-25
4*	J:125494 Ohazama A, Sharpe PT, TFII-I gene family during tooth development: Candidate genes for tooth anomalies in Williams syndrome. Dev Dyn. 2007 Oct;236(10):2884-8
1	J:285870 Sakurai T, Dorr NP, Takahashi N, McInnes LA, Elder GA, Buxbaum JD, Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions. Autism Res. 2011 Feb;4(1):28-39
8*	J:43550 Wang YK, Perez-Jurado LA, Francke U, A mouse single-copy gene, Gtf2i, the homolog of human GTF2I, that is duplicated in the Williams-Beuren syndrome deletion region. Genomics. 1998 Mar 1;48(2):163-70
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
1	J:235644 Wu Y, Wei FY, Kawarada L, Suzuki T, Araki K, Komohara Y, Fujimura A, Kaitsuka T, Takeya M, Oike Y, Suzuki T, Tomizawa K, Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury. PLoS Genet. 2016 Sep;12(9):e1006355
1*	J:102143 Yoshikawa T, Piao Y, Zhong J, Matoba R, Carter MG, Wang Y, Goldberg I, Ko MS, High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization. Gene Expr Patterns. 2006 Jan;6(2):213-24