Gene Expression Literature Summary

• Symbol: Birc5
• Name: baculoviral IAP repeat-containing 5
• ID: MGI:1203517

68 matching records from 68 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E3.5	E8	E8.5	E9.5	E10.5	E11	E11.5	E12	E12.5	E13.5	E14	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)					2	1	2		1			2		5	4		3	3		1	1	2	4
In situ RNA (section)										1	1	1	1	7	2	1		2	1			1	6
Immunohistochemistry (whole mount)	1	1	1													1							1
In situ RNA (whole mount)							1								2
Northern blot									1						1								1
Western blot								1	1			1		1	2					1			2
RT-PCR		1		1		1	1		2		2	1		4	3		2	2		3		1	13
cDNA clones																1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Birc5  baculoviral IAP repeat-containing 5   (Synonyms: Api4, survivin, TIAP)
Results	Reference
1	J:166903 Aboualaiwi WA, Ratnam S, Booth RL, Shah JV, Nauli SM, Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation. Hum Mol Genet. 2011 Jan 15;20(2):354-67
3	J:45193 Adida C, Crotty PL, McGrath J, Berrebi D, Diebold J, Altieri DC, Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am J Pathol. 1998 Jan;152(1):43-9
2	J:314667 Bais AS, Cerqueira DM, Clugston A, Bodnar AJ, Ho J, Kostka D, Single-cell RNA sequencing reveals differential cell cycle activity in key cell populations during nephrogenesis. Sci Rep. 2021 Nov 17;11(1):22434
1	J:209511 Basu S, Rajakaruna S, De Arcangelis A, Zhang L, Georges-Labouesse E, Menko AS, alpha6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation. J Biol Chem. 2014 Feb 14;289(7):3842-55
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
5*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
3	J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17
4	J:160856 Coremans V, Ahmed T, Balschun D, D'Hooge R, DeVriese A, Cremer J, Antonucci F, Moons M, Baekelandt V, Reumers V, Cremer H, Eisch A, Lagace D, Janssens T, Bozzi Y, Caleo M, Conway EM, Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin. BMC Neurosci. 2010;11:2
1	J:185743 Cotney J, Leng J, Oh S, DeMare LE, Reilly SK, Gerstein MB, Noonan JP, Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb. Genome Res. 2012 Jun;22(6):1069-80
1	J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227
2	J:242861 Damiani D, Goffinet AM, Alberts A, Tissir F, Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors. Nat Commun. 2016 Nov 16;7:13509
1	J:243698 Decaens T, Godard C, de Reynies A, Rickman DS, Tronche F, Couty JP, Perret C, Colnot S, Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology. 2008 Jan;47(1):247-58
1	J:337788 Descovich CP, Lough KJ, Jena A, Wu JJ, Yom J, Spitzer DC, Uppalapati M, Kedziora KM, Williams SE, AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis. Elife. 2023 Apr 5;12
2	J:77297 Di Cunto F, Imarisio S, Hirsch E, Broccoli V, Bulfone A, Migheli A, Atzori C, Turco E, Triolo R, Dotto GP, Silengo L, Altruda F, Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis. Neuron. 2000 Oct;28(1):115-27
1	J:242729 Ding X, Bloch W, Iden S, Ruegg MA, Hall MN, Leptin M, Partridge L, Eming SA, mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nat Commun. 2016 Oct 27;7:13226
2	J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82
1	J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23
1*	J:195084 Feng R, Zhou S, Liu Y, Song D, Luan Z, Dai X, Li Y, Tang N, Wen J, Li L, Sox2 protects neural stem cells from apoptosis via up-regulating survivin expression. Biochem J. 2013 Mar 15;450(3):459-68
1	J:307272 Godin P, Tsoi M, Paquet M, Boerboom D, YAP and TAZ are required for the postnatal development and the maintenance of the structural integrity of the oviduct. Reproduction. 2020 Aug;160(2):307-318
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
2	J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943
2	J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818
1	J:169736 Gualco E, Urbanska K, Perez-Liz G, Sweet T, Peruzzi F, Reiss K, Del Valle L, IGF-IR-dependent expression of Survivin is required for T-antigen-mediated protection from apoptosis and proliferation of neural progenitors. Cell Death Differ. 2010 Mar;17(3):439-51
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:272342 Hammond TR, Dufort C, Dissing-Olesen L, Giera S, Young A, Wysoker A, Walker AJ, Gergits F, Segel M, Nemesh J, Marsh SE, Saunders A, Macosko E, Ginhoux F, Chen J, Franklin RJM, Piao X, McCarroll SA, Stevens B, Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes. Immunity. 2019 Jan 15;50(1):253-271.e6
1	J:170963 Heallen T, Zhang M, Wang J, Bonilla-Claudio M, Klysik E, Johnson RL, Martin JF, Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size. Science. 2011 Apr 22;332(6028):458-61
1	J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253
1	J:304356 Hermann A, Wu G, Nedvetsky PI, Brucher VC, Egbring C, Bonse J, Hoffken V, Wennmann DO, Marks M, Krahn MP, Scholer H, Heiduschka P, Pavenstadt H, Kremerskothen J, The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice. Cell Death Dis. 2021 Jan 22;12(1):117
1	J:336923 Jiang X, Cheng Y, Zhu Y, Xu C, Li Q, Xing X, Li W, Zou J, Meng L, Azhar M, Cao Y, Tong X, Qin W, Zhu X, Bao J, Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice. Nat Commun. 2023 Jun 22;14(1):3729
4	J:141886 Jiang Y, Nishimura W, Devor-Henneman D, Kusewitt D, Wang H, Holloway MP, Dohi T, Sabo E, Robinson ML, Altieri DC, Sharma A, Altura RA, Postnatal expansion of the pancreatic beta-cell mass is dependent on survivin. Diabetes. 2008 Oct;57(10):2718-27
1	J:172677 Kang BH, Xia F, Pop R, Dohi T, Socolovsky M, Altieri DC, Developmental Control of Apoptosis by the Immunophilin Aryl Hydrocarbon Receptor-interacting Protein (AIP) Involves Mitochondrial Import of the Survivin Protein. J Biol Chem. 2011 May 13;286(19):16758-67
2	J:322702 Kaplan MM, Flucher BE, Counteractive and cooperative actions of muscle beta-catenin and CaV1.1 during early neuromuscular synapse formation. iScience. 2022 Apr 15;25(4):104025
4	J:82848 Kawamura K, Sato N, Fukuda J, Kodama H, Kumagai J, Tanikawa H, Shimizu Y, Tanaka T, Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos. Dev Biol. 2003 Apr 15;256(2):331-41
8*	J:53045 Kobayashi K, Hatano M, Otaki M, Ogasawara T, Tokuhisa T, Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1457-62
1	J:134270 Lee JH, Kim TS, Yang TH, Koo BK, Oh SP, Lee KP, Oh HJ, Lee SH, Kong YY, Kim JM, Lim DS, A crucial role of WW45 in developing epithelial tissues in the mouse. EMBO J. 2008 Apr 23;27(8):1231-42
1	J:148443 Levkau B, Schafers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, Kawaguchi N, Kirchhof P, Fabritz L, Stypmann J, Stegger L, Flogel U, Schrader J, Fischer JW, Hsieh P, Ou YL, Mehrhof F, Tiemann K, Ghanem A, Matus M, Neumann J, Heusch G, Schmid KW, Conway EM, Baba HA, Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation. 2008 Mar 25;117(12):1583-93
2	J:337931 Li L, Sun Y, Davis AE, Shah SH, Hamed LK, Wu MR, Lin CH, Ding JB, Wang S, Mettl14-mediated m(6)A modification ensures the cell-cycle progression of late-born retinal progenitor cells. Cell Rep. 2023 Jun 1;42(6):112596
1	J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249
1*	J:171624 Machold R, Klein C, Fishell G, Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip. Gene Expr Patterns. 2011 Jun-Jul;11(5-6):349-59
1	J:267771 Mamidi A, Prawiro C, Seymour PA, de Lichtenberg KH, Jackson A, Serup P, Semb H, Mechanosignalling via integrins directs fate decisions of pancreatic progenitors. Nature. 2018 Dec;564(7734):114-118
1	J:289490 Menard A, Abou Nader N, Levasseur A, St-Jean G, Le Roy MLG, Boerboom D, Benoit-Biancamano MO, Boyer A, Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate. Endocrinology. 2020 May 1;161(5)
3*	J:96853 Mukhopadhyay P, Greene RM, Zacharias W, Weinrich MC, Singh S, Young WW Jr, Pisano MM, Developmental gene expression profiling of mammalian, fetal orofacial tissue. Birth Defects Res A Clin Mol Teratol. 2004 Dec;70(12):912-26
1	J:272251 Noguchi S, Honda S, Saitoh T, Matsumura H, Nishimura E, Akira S, Shimizu S, Beclin 1 regulates recycling endosome and is required for skin development in mice. Commun Biol. 2019;2:37
1*	J:198109 Oeschger FM, Wang WZ, Lee S, Garcia-Moreno F, Goffinet AM, Arbones ML, Rakic S, Molnar Z, Gene expression analysis of the embryonic subplate. Cereb Cortex. 2012 Jun;22(6):1343-59
1*	J:142508 Ota M, Sasaki H, Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling. Development. 2008 Dec;135(24):4059-69
1	J:296391 Pan MH, Ju JQ, Li XH, Xu Y, Wang JD, Ren YP, Lu X, Sun SC, Inhibition of survivin induces spindle disorganization, chromosome misalignment, and DNA damage during mouse embryo development. Cell Cycle. 2020 Sep;19(17):2148-2157
1	J:240000 Park JY, Hughes LJ, Moon UY, Park R, Kim SB, Tran K, Lee JS, Cho SH, Kim S, The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state. Development. 2016 Jan 01;143(1):133-46
1	J:315122 Passer D, van de Vrugt A, Atmanli A, Domian IJ, Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation. Cell Rep. 2016 Feb 23;14(7):1662-1672
1*	J:193554 Pelikan RC, Iwata J, Suzuki A, Chai Y, Hacia JG, Identification of candidate downstream targets of TGFbeta signaling during palate development by genome-wide transcript profiling. J Cell Biochem. 2013 Apr;114(4):796-807
1	J:282460 Rong Y, Ji SY, Zhu YZ, Wu YW, Shen L, Fan HY, ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation. Nucleic Acids Res. 2019 Dec 2;47(21):11387-11402
1	J:305421 Rosin JM, Sinha S, Biernaskie J, Kurrasch DM, A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors. Dev Cell. 2021 May 3;56(9):1326-1345.e6
1	J:86350 Schwab K, Patterson LT, Aronow BJ, Luckas R, Liang HC, Potter SS, A catalogue of gene expression in the developing kidney. Kidney Int. 2003 Nov;64(5):1588-604
1	J:286313 Shea CA, Rolfe RA, McNeill H, Murphy P, Localization of YAP activity in developing skeletal rudiments is responsive to mechanical stimulation. Dev Dyn. 2020 Apr;249(4):523-542
1	J:297664 Simonson L, Vold S, Mowers C, Massey RJ, Ong IM, Longley BJ, Chang H, Keratin 13 deficiency causes white sponge nevus in mice. Dev Biol. 2020 Dec 1;468(1-2):146-153
1	J:156541 Song H, Mak KK, Topol L, Yun K, Hu J, Garrett L, Chen Y, Park O, Chang J, Simpson RM, Wang CY, Gao B, Jiang J, Yang Y, Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1431-6
2	J:336298 Taliani V, Buonaiuto G, Desideri F, Setti A, Santini T, Galfre S, Schirone L, Mariani D, Frati G, Valenti V, Sciarretta S, Perlas E, Nicoletti C, Musaro A, Ballarino M, The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart. Elife. 2023 Mar 6;12
1*	J:314103 Ulmke PA, Sakib MS, Ditte P, Sokpor G, Kerimoglu C, Pham L, Xie Y, Mao X, Rosenbusch J, Teichmann U, Nguyen HP, Fischer A, Eichele G, Staiger JF, Tuoc T, Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Stem Cell Reports. 2021 Apr 13;16(4):968-984
1	J:194895 Upadhya D, Ogata M, Reneker LW, MAPK1 is required for establishing the pattern of cell proliferation and for cell survival during lens development. Development. 2013 Apr;140(7):1573-82
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:140089 Wang RH, Sengupta K, Li C, Kim HS, Cao L, Xiao C, Kim S, Xu X, Zheng Y, Chilton B, Jia R, Zheng ZM, Appella E, Wang XW, Ried T, Deng CX, Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell. 2008 Oct 7;14(4):312-23
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
1	J:209317 Wilcox CL, Terry NA, May CL, Arx polyalanine expansion in mice leads to reduced pancreatic alpha-cell specification and increased alpha-cell death. PLoS One. 2013;8(11):e78741
4*	J:219386 Williams SE, Ratliff LA, Postiglione MP, Knoblich JA, Fuchs E, Par3-mInsc and Galphai3 cooperate to promote oriented epidermal cell divisions through LGN. Nat Cell Biol. 2014 Aug;16(8):758-69
4	J:151770 Wu X, Wang L, Schroer S, Choi D, Chen P, Okada H, Woo M, Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice. Diabetologia. 2009 Oct;52(10):2130-41
1*	J:135988 Yamanaka Y, Heike T, Kumada T, Shibata M, Takaoka Y, Kitano A, Shiraishi K, Kato T, Nagato M, Okawa K, Furushima K, Nakao K, Nakamura Y, Taketo MM, Aizawa S, Nakahata T, Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality. Mech Dev. 2008 May-Jun;125(5-6):441-50
1	J:273437 Yu W, Ma X, Xu J, Heumuller AW, Fei Z, Feng X, Wang X, Liu K, Li J, Cui G, Peng G, Ji H, Li J, Jing N, Song H, Lin Z, Zhao Y, Wang Z, Zhou B, Zhang L, VGLL4 plays a critical role in heart valve development and homeostasis. PLoS Genet. 2019 Feb;15(2):e1007977
1	J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110
1	J:145436 Zwerts F, Lupu F, De Vriese A, Pollefeyt S, Moons L, Altura RA, Jiang Y, Maxwell PH, Hill P, Oh H, Rieker C, Collen D, Conway SJ, Conway EM, Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure. Blood. 2007 Jun 1;109(11):4742-52