Gene Expression Literature Summary

• Symbol: Slc6a2
• Name: solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
• ID: MGI:1270850

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E18.5	P
Immunohistochemistry (section)	1		1						3
In situ RNA (section)		1		2	2	1	1	1	4
In situ reporter (knock in)									2
Western blot									2
RT-PCR	1	1	1		1		1	1	3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Slc6a2  solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2   (Synonyms: NET, NE transporter, norepinephrine transporter, Slc6a5)
Results	Reference
1*	J:333232 Chen J, Cheng M, Wang L, Zhang L, Xu D, Cao P, Wang F, Herzog H, Song S, Zhan C, A Vagal-NTS Neural Pathway that Stimulates Feeding. Curr Biol. 2020 Oct 19;30(20):3986-3998.e5
1*	J:122059 Dahlin A, Xia L, Kong W, Hevner R, Wang J, Expression and immunolocalization of the plasma membrane monoamine transporter in the brain. Neuroscience. 2007 May 25;146(3):1193-211
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:226032 Genestine M, Lin L, Durens M, Yan Y, Jiang Y, Prem S, Bailoor K, Kelly B, Sonsalla PK, Matteson PG, Silverman J, Crawley JN, Millonig JH, DiCicco-Bloom E, Engrailed-2 (En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior. Hum Mol Genet. 2015 Oct 15;24(20):5805-27
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:274000 Hadden C, Fahmi T, Cooper A, Savenka AV, Lupashin VV, Roberts DJ, Maroteaux L, Hauguel-de Mouzon S, Kilic F, Serotonin transporter protects the placental cells against apoptosis in caspase 3-independent pathway. J Cell Physiol. 2017 Dec;232(12):3520-3529
2	J:138599 Hong SJ, Lardaro T, Oh MS, Huh Y, Ding Y, Kang UJ, Kirfel J, Buettner R, Kim KS, Regulation of the noradrenaline neurotransmitter phenotype by the transcription factor AP-2beta. J Biol Chem. 2008 Jun 13;283(24):16860-7
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
11	J:166738 Li Z, Caron MG, Blakely RD, Margolis KG, Gershon MD, Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression. J Neurosci. 2010 Dec 8;30(49):16730-40
1*	J:193822 Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S, Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
1*	J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:343072 Vermeiren S, Cabochette P, Dannawi M, Desiderio S, San Jose AS, Achouri Y, Kricha S, Sitte M, Salinas-Riester G, Vanhollebeke B, Brunet JF, Bellefroid EJ, Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia. iScience. 2023 Dec 15;26(12):108364
1	J:314661 Zhang Q, Huang R, Ye Y, Guo X, Lu J, Zhu F, Gong X, Zhang Q, Yan J, Luo L, Zhuang S, Chen Y, Zhao X, Evans SM, Jiang C, Liang X, Sun Y, Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification. Cell Death Dis. 2018 Feb 14;9(2):247