Symbol Name ID |
Patj
PATJ, crumbs cell polarity complex component MGI:1277960 |
Age | E0.5 | E1 | E2 | E2.5 | E3 | E3.5 | E8 | E9.5 | E12.5 | E13.5 | E14.5 | E16.5 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 2 | 4 | 1 | 2 | 1 | 1 | 2 | |||||||
Immunohistochemistry (whole mount) | 1 | 1 | 1 | 1 | 1 | 1 | |||||||||
Western blot | 1 | 1 | 1 | ||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||||||
cDNA clones | 1 |
Patj PATJ, crumbs cell polarity complex component (Synonyms: Cipp, Inadl) | |
Results | Reference |
1 | J:148418 Adachi M, Hamazaki Y, Kobayashi Y, Itoh M, Tsukita S, Furuse M, Tsukita S, Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins. Mol Cell Biol. 2009 May;29(9):2372-89 |
2* | J:191149 Alves CH, Sanz Sanz A, Park B, Pellissier LP, Tanimoto N, Beck SC, Huber G, Murtaza M, Richard F, Sridevi Gurubaran I, Garcia Garrido M, Levelt CN, Rashbass P, Le Bivic A, Seeliger MW, Wijnholds J, Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet. 2013 Jan 1;22(1):35-50 |
1 | J:88495 Chae TH, Kim S, Marz KE, Hanson PI, Walsh CA, The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Nat Genet. 2004 Mar;36(3):264-70 |
1 | J:184469 Cho SH, Kim JY, Simons DL, Song JY, Le JH, Swindell EC, Jamrich M, Wu SM, Kim S, Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis. Hum Mol Genet. 2012 Jun 15;21(12):2663-76 |
1 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
1 | J:316286 Francou A, Saint-Michel E, Mesbah K, Kelly RG, TBX1 regulates epithelial polarity and dynamic basal filopodia in the second heart field. Development. 2014 Nov;141(22):4320-31 |
1 | J:220469 Grego-Bessa J, Hildebrand J, Anderson KV, Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development. 2015 Apr 1;142(7):1305-14 |
13* | J:260419 Jiang X, An W, Yang X, Lin J, Ma S, Wang D, Tang S, Asymmetric distribution of CRUMBS polarity complex proteins from compacted 8-cell to blastocyst stage during mouse preimplantation development. Gene Expr Patterns. 2018 Jan;27:93-98 |
3* | J:220858 Kim JY, Song JY, Karnam S, Park JY, Lee JJ, Kim S, Cho SH, Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye. Gene Expr Patterns. 2015 Jan;17(1):31-7 |
2 | J:160624 Kim S, Lehtinen MK, Sessa A, Zappaterra MW, Cho SH, Gonzalez D, Boggan B, Austin CA, Wijnholds J, Gambello MJ, Malicki J, LaMantia AS, Broccoli V, Walsh CA, The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron. 2010 Apr 15;66(1):69-84 |
1 | J:238551 Ramkumar N, Omelchenko T, Silva-Gagliardi NF, McGlade CJ, Wijnholds J, Anderson KV, Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation. Nat Cell Biol. 2016 Dec;18(12):1281-1291 |
3 | J:134686 Srinivasan K, Roosa J, Olsen O, Lee SH, Bredt DS, McConnell SK, MALS-3 regulates polarity and early neurogenesis in the developing cerebral cortex. Development. 2008 May;135(10):1781-90 |
1 | J:206750 Whiteman EL, Fan S, Harder JL, Walton KD, Liu CJ, Soofi A, Fogg VC, Hershenson MB, Dressler GR, Deutsch GH, Gumucio DL, Margolis B, Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol. 2014 Jan;34(1):43-56 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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