About   Help   FAQ
Gene Expression Literature Summary
Symbol
Name
ID
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
MGI:1277989

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9 E11 E11.5 E12.5 E13 E13.5 E14.5 E15 E17 P
Immunohistochemistry (section) 1
In situ RNA (section) 1
Western blot 1 1 1 1
RT-PCR 1 1 1 1 2 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Shmt2  serine hydroxymethyltransferase 2 (mitochondrial)   (Synonyms: 2700043D08Rik)
Results  Reference
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*J:241343 Furuya S, Yoshida K, Kawakami Y, Yang JH, Sayano T, Azuma N, Tanaka H, Kuhara S, Hirabayashi Y, Inactivation of the 3-phosphoglycerate dehydrogenase gene in mice: changes in gene expression and associated regulatory networks resulting from serine deficiency. Funct Integr Genomics. 2008 Aug;8(3):235-49
6*J:312368 Imbard A, Schwendimann L, Lebon S, Gressens P, Blom HJ, Benoist JF, Liver and brain differential expression of one-carbon metabolism genes during ontogenesis. Sci Rep. 2021 Oct 26;11(1):21132
1J:267504 Kiyama T, Chen CK, Wang SW, Pan P, Ju Z, Wang J, Takada S, Klein WH, Mao CA, Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis. Mol Neurodegener. 2018 Oct 17;13(1):56
1J:357899 Li J, Zhang B, Li Y, Liu C, Tang X, Zhao J, Pei X, Li Y, Serine Hydroxymethyltransferase 2 Deficiency in the Hematopoietic System Disrupts Erythropoiesis and Induces Anemia in Murine Models. Int J Mol Sci. 2024 Oct 15;25(20)
1*J:147857 Liu SP, Li YS, Chen YJ, Chiang EP, Li AF, Lee YH, Tsai TF, Hsiao M, Huang SF, Chen YM, Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver. Hepatology. 2007 Nov;46(5):1413-25
4*J:259713 Tani H, Ohnishi S, Shitara H, Mito T, Yamaguchi M, Yonekawa H, Hashizume O, Ishikawa K, Nakada K, Hayashi JI, Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal. Sci Rep. 2018 Jan 11;8(1):425
1*J:321836 Zhao K, Huang X, Zhao W, Lu B, Yang Z, LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. Development. 2022 Mar 15;149(6):dev200458

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory