Gene Expression Literature Summary

• Symbol: Nid2
• Name: nidogen 2
• ID: MGI:1298229

25 matching records from 25 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E4.5	E5.5	E6.5	E7.5	E8.5	E9.5	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15.5	E16	E16.5	E17	E17.5	E18.5	E	P
Immunohistochemistry (section)					1	2	1				2	1	2	1	2	2	2		1	1	1	1	3	1	6
In situ RNA (section)						1						2				2		1	1		1	1		1
In situ RNA (whole mount)								1	1				2					1
In situ reporter (knock in)																									1
Northern blot			1	1	1	1	1	1	1		1	1	1	1	1	1	1	1	1	1	1	1	2		1
Western blot																		1						1
RT-PCR	1	1						1	1			1				1			1						3
cDNA clones								1		1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nid2  nidogen 2   (Synonyms: entactin 2, entactin-2)
Results	Reference
3*	J:222615 Abe K, Yamamoto R, Franke V, Cao M, Suzuki Y, Suzuki MG, Vlahovicek K, Svoboda P, Schultz RM, Aoki F, The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing. EMBO J. 2015 Jun 3;34(11):1523-37
1	J:100029 Bader BL, Smyth N, Nedbal S, Miosge N, Baranowsky A, Mokkapati S, Murshed M, Nischt R, Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice. Mol Cell Biol. 2005 Aug;25(15):6846-56
1	J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51
1*	J:148410 Combes AN, Lesieur E, Harley VR, Sinclair AH, Little MH, Wilhelm D, Koopman P, Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Dev Dyn. 2009 May;238(5):1033-41
1	J:177724 Danussi C, Petrucco A, Wassermann B, Pivetta E, Modica TM, Belluz Ldel B, Colombatti A, Spessotto P, EMILIN1-alpha4/alpha9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation. J Cell Biol. 2011 Oct 3;195(1):131-45
2*	J:98797 Gersdorff N, Muller M, Otto S, Poschadel R, Hubner S, Miosge N, Basement membrane composition in the early mouse embryo day 7. Dev Dyn. 2005 May 13;233(3):1140-1148
4*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
5	J:345111 Jacobson KR, Saleh AM, Lipp SN, Tian C, Watson AR, Luetkemeyer CM, Ocken AR, Spencer SL, Kinzer-Ursem TL, Calve S, Extracellular matrix protein composition dynamically changes during murine forelimb development. iScience. 2024 Feb 16;27(2):108838
1	J:185210 Kiyozumi D, Takeichi M, Nakano I, Sato Y, Fukuda T, Sekiguchi K, Basement membrane assembly of the integrin alpha8beta1 ligand nephronectin requires Fraser syndrome-associated proteins. J Cell Biol. 2012 May 28;197(5):677-89
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:154054 Lange A, Wickstrom SA, Jakobson M, Zent R, Sainio K, Fassler R, Integrin-linked kinase is an adaptor with essential functions during mouse development. Nature. 2009 Oct 15;461(7266):1002-6
2*	J:90283 Leimeister C, Schumacher N, Diez H, Gessler M, Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein. Dev Dyn. 2004 Jun;230(2):371-7
1	J:175092 Liu J, He X, Qi Y, Tian X, Monkley SJ, Critchley DR, Corbett SA, Lowry SF, Graham AM, Li S, Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis. Mol Cell Biol. 2011 Aug;31(16):3366-77
1*	J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54
3	J:81596 Miosge N, Sasaki T, Timpl R, Evidence of nidogen-2 compensation for nidogen-1 deficiency in transgenic mice. Matrix Biol. 2002 Nov;21(7):611-21
3	J:167775 Mokkapati S, Fleger-Weckmann A, Bechtel M, Koch M, Breitkreutz D, Mayer U, Smyth N, Nischt R, Basement Membrane Deposition of Nidogen 1 but Not Nidogen 2 Requires the Nidogen Binding Module of the Laminin {gamma}1 Chain. J Biol Chem. 2011 Jan 21;286(3):1911-8
2	J:65651 Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG, Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mech Dev. 2000 Nov;98(1-2):77-94
1*	J:85732 Petiot A, Conti FJ, Grose R, Revest JM, Hodivala-Dilke KM, Dickson C, A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning. Development. 2003 Nov;130(22):5493-501
31*	J:79202 Salmivirta K, Talts JF, Olsson M, Sasaki T, Timpl R, Ekblom P, Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens. Exp Cell Res. 2002 Oct 1;279(2):188-201
2	J:190524 Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, Xu J, Sadovsky Y, Barak Y, Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
1	J:81766 Smits P, Lefebvre V, Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs. Development. 2003 Mar;130(6):1135-48
2	J:167396 Szabova L, Son MY, Shi J, Sramko M, Yamada SS, Swaim WD, Zerfas P, Kahan S, Holmbeck K, Membrane-type MMPs are indispensable for placental labyrinth formation and development. Blood. 2010 Dec 16;116(25):5752-61
9	J:108466 Tomte LT, Annatshah Y, Schluter NK, Miosge N, Herken R, Quondamatteo F, Hematopoietic cells are a source of nidogen-1 and nidogen-2 during mouse liver development. J Histochem Cytochem. 2006 May;54(5):593-604
2	J:76368 Willem M, Miosge N, Halfter W, Smyth N, Jannetti I, Burghart E, Timpl R, Mayer U, Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development. Development. 2002 Jun;129(11):2711-22
2*	J:328233 Zhang JL, Richetti S, Ramezani T, Welcker D, Lutke S, Pogoda HM, Hatzold J, Zaucke F, Keene DR, Bloch W, Sengle G, Hammerschmidt M, Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2. Matrix Biol. 2022 Aug 22;