Gene Expression Literature Summary

• Symbol: Sncg
• Name: synuclein, gamma
• ID: MGI:1298397

31 matching records from 31 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E18	E18.5	E19	E	P
Immunohistochemistry (section)				1		1			2			2	1	1	1		2	2	1	1	6
In situ RNA (section)		1	1	1	2	1	1		1		8		5		3			1			6
In situ RNA (whole mount)				1																	1
Northern blot		1		1		1		1		1		1		1		1	1				2
Western blot		1		1		1		1				1				1					6
RT-PCR	1			1							2	1			1	1					3
cDNA clones								1													1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sncg  synuclein, gamma   (Synonyms: C79089, persyn)
Results	Reference
5	J:141972 Akil O, Weber CM, Park SN, Ninkina N, Buchman V, Lustig LR, Localization of synucleins in the Mammalian cochlea. J Assoc Res Otolaryngol. 2008 Dec;9(4):452-63
3	J:49830 Buchman VL, Adu J, Pinon LG, Ninkina NN, Davies AM, Persyn, a member of the synuclein family, influences neurofilament network integrity. Nat Neurosci. 1998 Jun;1(2):101-3
23	J:50900 Buchman VL, Hunter HJ, Pinon LG, Thompson J, Privalova EM, Ninkina NN, Davies AM, Persyn, a member of the synuclein family, has a distinct pattern of expression in the developing nervous system. J Neurosci. 1998 Nov 15;18(22):9335-41
1	J:353339 Butts JC, Wu SR, Durham MA, Dhindsa RS, Revelli JP, Ljungberg MC, Saulnier O, McLaren ME, Taylor MD, Zoghbi HY, A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain. Dev Cell. 2024 Aug 19;59(16):2171-2188.e7
1	J:322321 Catela C, Chen Y, Weng Y, Wen K, Kratsios P, Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. Elife. 2022 Mar 22;11:e70766
2	J:265843 Chowdhury R, Laboissonniere LA, Wester AK, Muller M, Trimarchi JM, The Trim family of genes and the retina: Expression and functional characterization. PLoS One. 2018;13(9):e0202867
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4	J:356661 Esteban-Martinez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Marino G, Seco E, Durand S, Enot D, Grana O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P, Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017 Jun 14;36(12):1688-1706
2*	J:350259 Fernandez-Nogales M, Lopez-Cascales MT, Murcia-Belmonte V, Escalante A, Fernandez-Albert J, Munoz-Viana R, Barco A, Herrera E, Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding. Adv Sci (Weinh). 2022 Oct;9(29):e2200615
1	J:249145 Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM, Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878
2	J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194
1*	J:109593 Heanue TA, Pachnis V, Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes. Proc Natl Acad Sci U S A. 2006 May 2;103(18):6919-24
1	J:284156 Lo Giudice Q, Leleu M, La Manno G, Fabre PJ, Single-cell transcriptional logic of cell-fate specification and axon guidance in early-born retinal neurons. Development. 2019 Sep 9;146(17):dev178103
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2	J:167071 Mao CA, Tsai WW, Cho JH, Pan P, Barton MC, Klein WH, Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development. Dev Biol. 2011 Jan 1;349(1):90-9
1	J:141248 Mao CA, Wang SW, Pan P, Klein WH, Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5. Development. 2008 Oct;135(20):3379-88
1*	J:278612 Miltner AM, Mercado-Ayon Y, Cheema SK, Zhang P, Zawadzki RJ, La Torre A, A Novel Reporter Mouse Uncovers Endogenous Brn3b Expression. Int J Mol Sci. 2019 Jun 14;20(12):2903
2*	J:88577 Mu X, Beremand PD, Zhao S, Pershad R, Sun H, Scarpa A, Liang S, Thomas TL, Klein WH, Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Development. 2004 Mar;131(6):1197-210
1	J:146349 Mu X, Fu X, Beremand PD, Thomas TL, Klein WH, Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2. Proc Natl Acad Sci U S A. 2008 May 13;105(19):6942-7
1	J:97089 Mu X, Fu X, Sun H, Liang S, Maeda H, Frishman LJ, Klein WH, Ganglion cells are required for normal progenitor- cell proliferation but not cell-fate determination or patterning in the developing mouse retina. Curr Biol. 2005 Mar 29;15(6):525-30
1	J:229930 Nechiporuk T, McGann J, Mullendorff K, Hsieh J, Wurst W, Floss T, Mandel G, The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Elife. 2016;5:e09584
6	J:86439 Ninkina N, Papachroni K, Robertson DC, Schmidt O, Delaney L, O'Neill F, Court F, Rosenthal A, Fleetwood-Walker SM, Davies AM, Buchman VL, Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene. Mol Cell Biol. 2003 Nov;23(22):8233-45
7*	J:133651 Oort PJ, Knotts TA, Grino M, Naour N, Bastard JP, Clement K, Ninkina N, Buchman VL, Permana PA, Luo X, Pan G, Dunn TN, Adams SH, Gamma-synuclein is an adipocyte-neuron gene coordinately expressed with leptin and increased in human obesity. J Nutr. 2008 May;138(5):841-8
1	J:160742 Pla P, Hirsch MR, Le Crom S, Reiprich S, Harley VR, Goridis C, Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors. Neural Dev. 2008;3:14
1	J:123264 Quina LA, Pak W, Lanier J, Banwait P, Gratwick K, Liu Y, Velasquez T, O'Leary DD, Goulding M, Turner EE, Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways. J Neurosci. 2005 Dec 14;25(50):11595-604
2	J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22
4	J:92213 Robertson DC, Schmidt O, Ninkina N, Jones PA, Sharkey J, Buchman VL, Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice. J Neurochem. 2004 Jun;89(5):1126-36
2	J:294332 Romanov RA, Tretiakov EO, Kastriti ME, Zupancic M, Haring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, Clotman F, Andrews WD, Parnavelas JG, Farlik M, Bock C, Adameyko I, Hokfelt T, Keimpema E, Harkany T, Molecular design of hypothalamus development. Nature. 2020 Jun;582(7811):246-252
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:270598 Tiklova K, Bjorklund AK, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, Volakakis N, Yokota C, Hilscher MM, Hauling T, Holmstrom F, Joodmardi E, Nilsson M, Parmar M, Perlmann T, Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development. Nat Commun. 2019 Feb 4;10(1):581
1	J:220735 Wu F, Kaczynski TJ, Sethuramanujam S, Li R, Jain V, Slaughter M, Mu X, Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1559-68