Gene Expression Literature Summary

• Symbol: Tff2
• Name: trefoil factor 2 (spasmolytic protein 1)
• ID: MGI:1306805

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9.5	E10.5	E11	E12.5	E13	E14.5	E15.5	E16	E16.5	E17	E17.5	E18.5	E19	E	P
Immunohistochemistry (section)										2			3			4
In situ RNA (section)							3						1	1		1
In situ RNA (whole mount)		1	1	1		1			1		1			1		1
RT-PCR	1	1			1		2	3		3		1	1	1	1	6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tff2  trefoil factor 2 (spasmolytic protein 1)   (Synonyms: mSP, SP)
Results	Reference
3*	J:80501 Gitton Y, Dahmane N, Baik S, Ruiz I Altaba A, Neidhardt L, Scholze M, Herrmann BG, Kahlem P, Benkahla A, Schrinner S, Yildirimman R, Herwig R, Lehrach H, Yaspo ML, A gene expression map of human chromosome 21 orthologues in the mouse. Nature. 2002 Dec 5;420(6915):586-90
1*	J:89882 Hansen TV, Hammer NA, Nielsen J, Madsen M, Dalbaeck C, Wewer UM, Christiansen J, Nielsen FC, Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice. Mol Cell Biol. 2004 May;24(10):4448-64
1	J:314579 Higashiguchi Y, Katsuta K, Minegishi T, Yonemura S, Urasaki A, Inagaki N, Identification of a shootin1 isoform expressed in peripheral tissues. Cell Tissue Res. 2016 Oct;366(1):75-87
7	J:275470 Hirata K, Kodama S, Nakano Y, Minaki-Nakagawa Y, Aoyama Y, Sakikubo M, Goto T, Yoshida M, Masui T, Yamamoto T, Uemoto S, Kawaguchi Y, Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis. Sci Rep. 2019 Feb 7;9(1):1636
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1	J:185603 Li S, Wang Y, Zhang Y, Lu MM, Demayo FJ, Dekker JD, Tucker PW, Morrisey EE, Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development. 2012 Jul;139(14):2500-9
2	J:261627 Mori K, Nakamura H, Kurooka H, Miyachi H, Tamada K, Sugai M, Takumi T, Yokota Y, Id2 determines intestinal identity through repression of the foregut transcription factor, Irx5. Mol Cell Biol. 2018 Feb 20;
6	J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310
5	J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461
8	J:55235 Otto WR, Patel K, Trefoil factor family (TFF)-domain peptides in the mouse: embryonic gastrointestinal expression and wounding response. Anat Embryol (Berl). 1999 Jun;199(6):499-508
1	J:122531 Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan BL, Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development. 2007 Jul;134(13):2521-31
7*	J:80502 Reymond A, Marigo V, Yaylaoglu MB, Leoni A, Ucla C, Scamuffa N, Caccioppoli C, Dermitzakis ET, Lyle R, Banfi S, Eichele G, Antonarakis SE, Ballabio A, Human chromosome 21 gene expression atlas in the mouse. Nature. 2002 Dec 5;420(6915):582-6
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6